#hcv — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #hcv, aggregated by home.social.
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Acute and chronic infections drive distinct trajectories in human memory CD4+ T cell formation.
CD4⁺ T cell fates in #HCV differ by outcome, revealing distinct chronic, cleared, and cured memory paths.
https://www.sciencedirect.com/science/article/pii/S1074761326001196 #hepatitis #immunology #microbiology #virology
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Excited to share our paper in Journal of Medicinal #Chemistry exploring carbobicyclic nucleoside analogues as potential #antivirals!
We swapped the ribose oxygen for a carbon in nucleoside analogues and explored this novel scaffold.
From our library, several compounds showed activity against #HCV, #HSV, #influenza, and #RSV. One uracil-based analogue stood out by inhibiting multiple viruses like #flu and HCV. Modeling suggests it “locks” the viral active site instead of being incorporated into RNA.
What really surprised us: nucleobases with known antiviral effects (like NHC from molnupiravir) didn’t work in our scaffold—but unmodified uracil did. The scaffold itself changes how these molecules behave.
Encouragingly, these compounds phosphorylate efficiently in cells without needing prodrugs, don't inhibit human polymerases, and our #synthesis is efficient: 28 pyrimidine and 35 purine analogues from just two intermediates in under 10 steps.
Huge thanks to all collaborators and colleagues who made this work possible!
https://pubs.acs.org/doi/10.1021/acs.jmedchem.5c02584
J. Med. Chem. 2026, 69, 5, 5501–5539.
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HLV Kim Sang Sik tuyên bố U22 Việt Nam đã sẵn sàng cho hành trình chinh phục Vòng chung kết U23 châu Á 2026, sau chiến thắng HCV tại SEA Games 33 ở Thái Lan. Ông nhấn mạnh tinh thần đoàn kết, sự tiến bộ rõ rệt của các cầu thủ và sự chuẩn bị kỹ lưỡng cho các thử thách lớn hơn ở cấp độ châu lục.
#U22Vietnam #VCKU23ChauA #KimSangSik #SEA Games #BongDa #U23Asia #VietnamFootball #HCV #TheThao #Football #AsianCup #HLV Kim Sang Sik
https://vietnamnet.vn/hlv-kim-sang-sik-noi-gi-khi-u22-viet-nam-gian
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Lời tâm đắc giúp U22 Việt Nam lội ngược dòng giành HCV SEA Games 33 vừa được các tuyển thủ tiết lộ: tinh thần "không bao giờ gục ngã" và niềm tin vào bản thân dù bị Thái Lan dẫn trước 2 bàn. Toàn đội đã đoàn kết, thi đấu quật khởi và tạo nên màn lội ngược dòng ngoạn mục. Một chiến thắng của ý chí và bản lĩnh!
#SEAGames33 #U22Vietnam #HCV #BongDaNam #SEA Games 33 #U22 Việt Nam #HuyChươngVàng #BóngĐáNam #TinhThan #VoDich #Champion
https://vtcnews.vn/he-lo-loi-tam-dac-giup-u22-viet-nam-nguoc-do
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Lời tâm đắc giúp U22 Việt Nam lội ngược dòng giành HCV SEA Games 33 vừa được các tuyển thủ tiết lộ: tinh thần "không bao giờ gục ngã" và niềm tin vào bản thân dù bị Thái Lan dẫn trước 2 bàn. Toàn đội đã đoàn kết, thi đấu quật khởi và tạo nên màn lội ngược dòng ngoạn mục. Một chiến thắng của ý chí và bản lĩnh!
#SEAGames33 #U22Vietnam #HCV #BongDaNam #SEA Games 33 #U22 Việt Nam #HuyChươngVàng #BóngĐáNam #TinhThan #VoDich #Champion
https://vtcnews.vn/he-lo-loi-tam-dac-giup-u22-viet-nam-nguoc-do
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📉 Wie steht es um Hepatitis in Deutschland?
Die Zahl gemeldeter #Hepatitis-B- und -C-Fälle ist 2024 leicht gesunken – bleibt aber hoch.
Die genauen #HBV- und #HCV- Zahlen, wie sie zu bewerten sind und wie es um den Stand der Elimination steht, im aktuellen EpidBull
🔗 https://www.rki.de/DE/Aktuelles/Publikationen/Epidemiologisches-Bulletin/2025/30_25.pdf
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📉 Wie steht es um Hepatitis in Deutschland?
Die Zahl gemeldeter #Hepatitis-B- und -C-Fälle ist 2024 leicht gesunken – bleibt aber hoch.
Die genauen #HBV- und #HCV- Zahlen, wie sie zu bewerten sind und wie es um den Stand der Elimination steht, im aktuellen EpidBull
🔗 https://www.rki.de/DE/Aktuelles/Publikationen/Epidemiologisches-Bulletin/2025/30_25.pdf
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📉 Wie steht es um Hepatitis in Deutschland?
Die Zahl gemeldeter #Hepatitis-B- und -C-Fälle ist 2024 leicht gesunken – bleibt aber hoch.
Die genauen #HBV- und #HCV- Zahlen, wie sie zu bewerten sind und wie es um den Stand der Elimination steht, im aktuellen EpidBull
🔗 https://www.rki.de/DE/Aktuelles/Publikationen/Epidemiologisches-Bulletin/2025/30_25.pdf
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📉 Wie steht es um Hepatitis in Deutschland?
Die Zahl gemeldeter #Hepatitis-B- und -C-Fälle ist 2024 leicht gesunken – bleibt aber hoch.
Die genauen #HBV- und #HCV- Zahlen, wie sie zu bewerten sind und wie es um den Stand der Elimination steht, im aktuellen EpidBull
🔗 https://www.rki.de/DE/Aktuelles/Publikationen/Epidemiologisches-Bulletin/2025/30_25.pdf
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📉 Wie steht es um Hepatitis in Deutschland?
Die Zahl gemeldeter #Hepatitis-B- und -C-Fälle ist 2024 leicht gesunken – bleibt aber hoch.
Die genauen #HBV- und #HCV- Zahlen, wie sie zu bewerten sind und wie es um den Stand der Elimination steht, im aktuellen EpidBull
🔗 https://www.rki.de/DE/Aktuelles/Publikationen/Epidemiologisches-Bulletin/2025/30_25.pdf
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R to @ECDC_EU: Approximately 3.6 million people in the EU/EEA are chronically infected with #hepatitisB virus (#HBV) and 1.8 with #hepatitisC virus (#HCV).
Check latest data: https://www.ecdc.europa.eu/en/news-events/high-burden-hepatitis-b-and-c-persists-eueea
[2024-07-28 17:52 UTC]
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R to @ECDC_EU: Approximately 3.6 million people in the EU/EEA are chronically infected with #hepatitisB virus (#HBV) and 1.8 with #hepatitisC virus (#HCV).
Check latest data: https://www.ecdc.europa.eu/en/news-events/high-burden-hepatitis-b-and-c-persists-eueea
[2024-07-28 17:52 UTC]
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R to @ECDC_EU: There are 3.6M people chronically infected with #HBV & 1.8M with #HCV in EU/EEA.
The prevalence of both infections varies across countries & populations, with the highest burden among vulnerable groups such as people who inject drugs, people in prison & some migrant populations.
[2024-04-25 17:54 UTC]
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R to @ECDC_EU: There are 3.6M people chronically infected with #HBV & 1.8M with #HCV in EU/EEA.
The prevalence of both infections varies across countries & populations, with the highest burden among vulnerable groups such as people who inject drugs, people in prison & some migrant populations.
[2024-04-25 17:54 UTC]
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A road map to #ViralHepatitis elimination in BC by 2030 | #BCMJ https://bcmj.org/bc-centre-disease-control/road-map-viral-hepatitis-elimination-bc-2030 “To reduce the impact of viral hepatitis, the Canadian government, in alignment with global efforts ..aims to eliminate both #hepatitis viruses as a #PublicHealth threat by 2030. To support this goal, the Public Health Agency of Canada set targets for the proportion of people living with chronic #HBV or #HCV infection in Canada to be diagnosed and treated by 2025 and 2030.”
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A road map to #ViralHepatitis elimination in BC by 2030 | #BCMJ https://bcmj.org/bc-centre-disease-control/road-map-viral-hepatitis-elimination-bc-2030 “To reduce the impact of viral hepatitis, the Canadian government, in alignment with global efforts ..aims to eliminate both #hepatitis viruses as a #PublicHealth threat by 2030. To support this goal, the Public Health Agency of Canada set targets for the proportion of people living with chronic #HBV or #HCV infection in Canada to be diagnosed and treated by 2025 and 2030.”
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RT Eurosurveillance
Our new issue marking #WorldHepatitisDay2023 is out with data on #HCV and #HBV in 🇬🇪 and updated #hepatitis B prevalence estimates for the 🇪🇺🇳🇴🇮🇸 🇱🇮 🇬🇧
👉🏽https://bit.ly/EUS2830
#WHD #HepatitisDay23 #NoHep #OneLifeOneLiver #publichealth #epidemiology #SDG3🐦🔗: https://n.respublicae.eu/Eurosurveillanc/status/1684582287776555009
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RT Eurosurveillance
Our new issue marking #WorldHepatitisDay2023 is out with data on #HCV and #HBV in 🇬🇪 and updated #hepatitis B prevalence estimates for the 🇪🇺🇳🇴🇮🇸 🇱🇮 🇬🇧
👉🏽https://bit.ly/EUS2830
#WHD #HepatitisDay23 #NoHep #OneLifeOneLiver #publichealth #epidemiology #SDG3🐦🔗: https://n.respublicae.eu/Eurosurveillanc/status/1684582287776555009
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RT Eurosurveillance
Re @ECDC_EU @eHealth_EU @EU_Health @emcdda @Hep_Alliance Research from 🇬🇪
a 📈 in #Hepatitis C #prevalence 2015-2021 indicates that the elimination programme has effectively tackled the country's #hepC #epidemic
Walker et al. validate & update projections of #HCV prevalence & incidence
➡️https://bit.ly/EUS2830HCV
#HepatitisDay23🐦🔗: https://n.respublicae.eu/Eurosurveillanc/status/1684843887280754688
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Our new paper on the long-term impact of opioid manufacturers' targeted marketing to docs in states with high cancer burdens in the 1990s. 25 years later: more deaths from hepatitis and infective endocarditis. #opioids #Purdue #OcyContin #HCV #HBV #endocarditis #epidemiology #causalinference
https://www.healthaffairs.org/doi/10.1377/hlthaff.2023.00146
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Our new paper on the long-term impact of opioid manufacturers' targeted marketing to docs in states with high cancer burdens in the 1990s. 25 years later: more deaths from hepatitis and infective endocarditis. #opioids #Purdue #OcyContin #HCV #HBV #endocarditis #epidemiology #causalinference
https://www.healthaffairs.org/doi/10.1377/hlthaff.2023.00146
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Our new paper on the long-term impact of opioid manufacturers' targeted marketing to docs in states with high cancer burdens in the 1990s. 25 years later: more deaths from hepatitis and infective endocarditis. #opioids #Purdue #OcyContin #HCV #HBV #endocarditis #epidemiology #causalinference
https://www.healthaffairs.org/doi/10.1377/hlthaff.2023.00146
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Our new paper on the long-term impact of opioid manufacturers' targeted marketing to docs in states with high cancer burdens in the 1990s. 25 years later: more deaths from hepatitis and infective endocarditis. #opioids #Purdue #OcyContin #HCV #HBV #endocarditis #epidemiology #causalinference
https://www.healthaffairs.org/doi/10.1377/hlthaff.2023.00146
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Our new paper on the long-term impact of opioid manufacturers' targeted marketing to docs in states with high cancer burdens in the 1990s. 25 years later: more deaths from hepatitis and infective endocarditis. #opioids #Purdue #OcyContin #HCV #HBV #endocarditis #epidemiology #causalinference
https://www.healthaffairs.org/doi/10.1377/hlthaff.2023.00146
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Viral hepatitis is a silent killer that should be confronted. Canada committed to eliminating #HBV and #HCV by 2030, but the plan is limping along
https://theglobeandmail.com/opinion/article-viral-hepatitis-is-a-silent-killer-that-canada-should-confront/?utm_medium=Referrer:+Social+Network+/+Media&utm_campaign=Shared+Web+Article+Links -
Our new article in Clinical Infectious Diseases.
Our new article in Clinical Infectious Diseases. HIV case rises are preceded by rises in other infections common among people who use drugs.
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RT @Eurosurveillanc: Our new issue is available
#Hepatitis #HBV #HCV #surveillance
#AMR #parasites #foodsafety #animalhealth #AntimicrobialResistance #IDTwitter #epidemiology #publichealth🐦🔗: https://n.respublicae.eu/ECDC_EU/status/1623707509105086469
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This is a tremendous piece of work by Nick Florko at #StatNews. Thousands of people are dying every year from #HCV--a curable viral illness--in American #prisons.
#publichealth
https://www.statnews.com/2022/12/15/hundreds-incarcerated-people-dying-hepatitis-c-despite-simple-cure/ -
My #introduction to #mastodon:
I'm a biostatistician researching #statistics #biostatistics #epidemiology #publichealth. I primarily work on #bayesian methods for spatio-temporal & environmental #epi and #publichealth surveillance -- often for overcoming challenges related to imperfect data & small areas.
Most of my work is in #substanceuse & the opioid syndemic #hiv #HCV #overdose.
I've also been working on disease mapping models for environmental exposures associated with #ClimateChange.
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There are still too many individuals unaware of PrEP. We need to do a better job of communicating, especially among people who would benefit most. From a recent study among people with Hep C (n = 314), only 27% had heard of PrEP, 10% had been offered, and only 6 people were taking PrEP.
#HIV #HCV #publichealth #health #healthcare
https://academic.oup.com/ofid/article/9/10/ofac476/6697961?login=false
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RT @Eurosurveillanc: New technology offers a variety of cost-effective rapid testing kits to improve access to testing
This perspective explores upsides, implications & necessary steps for the use of platforms for multi-disease testing for #TB #HIV #HCV #STI
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https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2022.27.29.2100930
#EuroTestWeek -
I believe an #introduction is in order.
I do #publichealth and #research. Specifically #ruralhealth. More specifically #HIV and #HCV. I left the other place some time ago for a mental health break.
I'm also a doctoral student and #skeptic, I love #running and #cooking and I have no time for #misinformation or #pseudoscience.
#Tooting to you from southwest Virginia, United States.
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Digging into a topic that's new to me -- hepatitis C treatment. Know someone who's doing interesting work in this area? Please point me their way! #hepatitisc #hcv
