#h3k27me3 — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #h3k27me3, aggregated by home.social.
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EZH2 (PRC2) trimethylates H3K27 → PRC1 recruitment → chromatin compaction → transcriptional silencing.
Elegant at the mechanistic level. Consequential at the organismal level — elevated EZH2 activity shortens lifespan in model organisms, likely via progressive silencing of stress-response loci.
The SET domain may be one of the most underrated targets in aging biology.
#EZH2 #PRC2 #Epigenetics #AgingBiology #H3K27me3 #ChromatinRemodeling #Longevity
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Repressed but ready to go: How #bivalency holds developmental #genes in a poised state for #expression.
#histones #H3K27me3 #H3K4me3 #Nucleosome #KAT6B
https://phys.org/news/2025-02-repressed-ready-bivalency-developmental-genes.html
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This fascinating study from Gao et al. suggests a new #epigenetic explanation of #heterosis in #Arabidopsis #hybrids--providing new insights into #crop breeding and yield increase.
https://doi.org/10.1111/jipb.13620
@wileyplantsci
#JIPB #PlantSci #CropSci #H3K27me3 #OpenAccess #PlantScience #botany -
This fascinating study from Gao et al. suggests a new #epigenetic explanation of #heterosis in #Arabidopsis #hybrids--providing new insights into #crop breeding and yield increase.
https://doi.org/10.1111/jipb.13620
@wileyplantsci
#JIPB #PlantSci #CropSci #H3K27me3 #OpenAccess #PlantScience #botany -
This fascinating study from Gao et al. suggests a new #epigenetic explanation of #heterosis in #Arabidopsis #hybrids--providing new insights into #crop breeding and yield increase.
https://doi.org/10.1111/jipb.13620
@wileyplantsci
#JIPB #PlantSci #CropSci #H3K27me3 #OpenAccess #PlantScience #botany -
This fascinating study from Gao et al. suggests a new #epigenetic explanation of #heterosis in #Arabidopsis #hybrids--providing new insights into #crop breeding and yield increase.
https://doi.org/10.1111/jipb.13620
@wileyplantsci
#JIPB #PlantSci #CropSci #H3K27me3 #OpenAccess #PlantScience #botany