#h18n11 — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #h18n11, aggregated by home.social.
-
Assessment of Quantitative #Genetic #Distances Supports the Separation of #H17N10 and #H18N11 Subtypes of #Influenza a Virus into a Distinct Species, https://etidiohnew.blogspot.com/2026/07/assessment-of-quantitative-genetic.html
-
Incompatible #packaging #signals and impaired #protein functions hinder #reassortment of #bat #H17N10 or #H18N11 segment 7 with #human #H1N1 #influenza A viruses, J Virol.: https://journals.asm.org/doi/abs/10.1128/jvi.00864-24?af=R
Recombinant PR8 viruses with bat influenza M open reading frames were generated but showed attenuation, which correlated with the functions of the bat M2 protein. Our studies provide novel insights into the molecular mechanisms that restrict reassortment between bat and conventional IAVs.
-
The #bat #Influenza A virus subtype #H18N11 induces nanoscale #MHCII #clustering upon host #cell #attachment, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.07.12.603249v1?rss=1
Both HA subtypes, H17 and H18, however, do not bind to sialic acids but instead engage a proteinaceous receptor: major histocompatibility complex class II (MHCII). The mechanistic details of this hitherto unknown protein-mediated entry are not understood.