#h10n5 — Public Fediverse posts

Immunoinformatics-Guided Design and In Silico Evaluation of a Multi-Epitope #Vaccine Against #Influenza A #H10N5 and #H3N2 Strains Based on HA and NA Proteins, https://etidiohnew.blogspot.com/2026/07/immunoinformatics-guided-design-and-in.html

Pathogenicity, #transmissibility, and #receptor #binding of a #human-isolated #influenza A #H10N5 virus, https://etidiohnew.blogspot.com/2025/07/pathogenicity-transmissibility-and.html

A #human-infecting #H10N5 avian #influenza virus: #clinical features, virus #reassortment, #receptor-binding affinity, and possible #transmission routes, https://etidiohnew.blogspot.com/2025/03/a-human-infecting-h10n5-avian-influenza.html

North #American-Origin #Influenza A (#H10) viruses in Eurasian Wild #Birds (2022–2024): Implications for the Emergence of Human #H10N5 Virus, https://etidiohnew.blogspot.com/2025/02/north-american-origin-influenza-h10.html

#Gene flow and its sporadic #spillover: #H10 and #N5 avian #influenza viruses from wild #birds and the #H10N5 #human cases in #China, https://etidiohnew.blogspot.com/2024/12/gene-flow-and-its-sporadic-spillover.html

#Epidemiology and #evolution of #human-origin #H10N5 #influenza virus

Source: One Health, AbstractH10 subtype avian influenza viruses were endemic in wild and domestic avian species worldwide. Strikingly, it frequently crossed the species barrier to infect mammalian hosts. Human infection with H10N3 and H10N8 were reported previously. Recently, a 63-year-old woman from Anhui province of China who died from a mixed infection of H3N2 and H10N5…

https://etidioh.wordpress.com/2024/10/09/epidemiology-and-evolution-of-human-origin-h10n5-influenza-virus/

''The HA #genes were part of the #American #lineage of #H10N5, showing 95.2% homology with A/Anser albifrons/South Korea/22JN-163-1/2022 (#H10N7) (GenBank: OQ296824.1). Conversely, the NA genes belonged to the #Eurasian lineage, with the highest homology (97.82%) to A/Spot-billed duck (Anas poecilohyncha)/Korea/KNU17/2022 (#H6N5) (GenBank: OR674089.1) ''

Outbreak Reports: A Retrospective #Investigation of a Case of Dual #Infection by #Avian-Origin #Influenza A (#H10N5) and Seasonal Influenza A (#H3N2) Viruses — #Anhui Province, #China, Dec '23–Jan '24, CCDC: https://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2024.106

This report documents the first human case of co-infection with avian-origin H10N5 and seasonal H3N2 influenza viruses. Epidemiological investigations identified H10N5 in environmental samples linked to the patient, but no transmission to close contacts occurred.

Avian #Influenza Virus and Avian #Paramyxoviruses in Wild #Waterfowl of the Western Coast of the #Caspian Sea (2017–2020), Viruses: https://www.mdpi.com/1999-4915/16/4/598

The following subtypes were determined and whole-genome nucleotide sequences of the isolated strains were obtained: #H1N1 (n = 2), #H3N8 (n = 8), #H4N6 (n = 2), #H7N3 (n = 2), #H8N4 (n = 1), #H10N5 (n = 1), and #H12N5 (n = 1). No high pathogenicity influenza virus H5 subtype was detected.

Avian #Influenza Virus and Avian #Paramyxoviruses in Wild #Waterfowl of the Western Coast of the #Caspian Sea (2017–2020), Viruses: https://www.mdpi.com/1999-4915/16/4/598

The following subtypes were determined and whole-genome nucleotide sequences of the isolated strains were obtained: #H1N1 (n = 2), #H3N8 (n = 8), #H4N6 (n = 2), #H7N3 (n = 2), #H8N4 (n = 1), #H10N5 (n = 1), and #H12N5 (n = 1). No high pathogenicity influenza virus H5 subtype was detected.

#Influenza at the #human-animal #interface - #Summary and #risk #assessment, from 22 December 2023 to 26 February 2024, WHO: https://www.who.int/publications/m/item/influenza-at-the-human-animal-interface-summary-and-assessment-26--february-2024

From 22 Dec 23 to 26 Feb 24, 5 cases of infection w flu #H5N1, 1 case of infection w an #H5N6 virus, 1 infection w an #H9N2 virus, 1 case of infection with an #H10N5 virus, & 2 cases of infection with #H1N1 #variant viruses were reported officially. Additionally, 1 case of infection with an #H9N2 #variant virus was detected.

Zoonotic #influenza: During period from 26 Sept 23 to 19 Feb 24, sporadic #zoonotic influenza cases were reported following exposure to infected birds & swine in most cases. 2 cases of #H5N6, 4 of #H9N2 & 1 of #H10N5 were reported in #China & 8 cases of #H5N1 were reported in #Cambodia. Single cases of #H1N1v were reported in #Brazil, #Spain & #Switzerland in this period. 1 case of #H1N2v was reported in the #UK. https://cdn.who.int/media/docs/default-source/influenza/who-influenza-recommendations/vcm-northern-hemisphere-recommendation-2024-2025/recommended-composition-of-influenza-virus-vaccines-for-use-in-the-2024-2025-northern-hemisphere-influenza-season.pdf?sfvrsn=2e9d2194_7&download=true

#WHO (13 February 2024). Disease #Outbreak #News; Avian #Influenza A(#H10N5) and Influenza A(#H3N2) #coinfection - #China. Available at https://www.who.int/emergencies/disease-outbreak-news/item/2023-DON504

-- 1 confirmed case of #human #coinfection with #H10N5 virus & seasonal influenza A(#H3N2). This is 1rst case of #human infection with avian influenza H10N5 reported globally. Case occurred in a female farmer over 60 yrs, with chronic comorbidities, from Anhui Province. Onset on 30 Nov 23 & passed away on 16 Dec 2023.

#China reported one #human #infection with Avian #influenza A(#H10N5) in #Zhejiang Province: a 63-year-old woman, with onset on November 30, 2023, was co-infected with influenza A(#H3N2). #HK CHP: https://www.chp.gov.hk/files/pdf/2024_avian_influenza_report_vol20_wk05.pdf

#HK CHP closely monitors #human case co-infected with avian #influenza A(#H10N5) and influenza A(#H3N2) on Mainland {#China}, https://www.info.gov.hk/gia/general/202401/31/P2024013100657.htm?fontSize=1

-- a 63-year-old female with underlying medical problems, who developed symptoms on Nov 30 last year and was admitted for treatment on December 2. She passed away on December 16. Her relevant close contacts did not show any abnormalities during the medical surveillance period.