#gramnegative — Public Fediverse posts

Experimental #antibiotic kills deadly #superbug, opens whole new class of #drugs
Relatively large molecule clogs a transport system, leading to lethal toxicity. In this case, the new #drug—dubbed #zosurabalpin—fights off the #GramNegative #bacterium carbapenem-resistant Acinetobacter baumannii, aka CRAB. Though it may sound obscure, it's an opportunistic, invasive #bacteria that often strikes hospitalized and critically ill patients, causing deadly #infections worldwide. https://arstechnica.com/science/2024/01/experimental-antibiotic-reveals-entirely-new-way-to-kill-drug-resistant-bacteria/

Experimental #antibiotic kills deadly #superbug, opens whole new class of #drugs
Relatively large molecule clogs a transport system, leading to lethal toxicity. In this case, the new #drug—dubbed #zosurabalpin—fights off the #GramNegative #bacterium carbapenem-resistant Acinetobacter baumannii, aka CRAB. Though it may sound obscure, it's an opportunistic, invasive #bacteria that often strikes hospitalized and critically ill patients, causing deadly #infections worldwide. https://arstechnica.com/science/2024/01/experimental-antibiotic-reveals-entirely-new-way-to-kill-drug-resistant-bacteria/

Start-Up Developing Precision Antibiotics for Resistant Bacteria

A company formed earlier this year is developing precision treatments for bacteria resistant to conventional antibiotics, and raising £4.3 million ($US 5.4 million) in seed funds.

https://sciencebusiness.technewslit.com/?p=45402

#News #Press #Science #Business #Biotechnology #Chemistry #Microbiology #GramNegative #Bacteria #AntiMicrobialResistance #Finance #SeedFunds

Start-Up Developing Precision Antibiotics for Resistant Bacteria

A company formed earlier this year is developing precision treatments for bacteria resistant to conventional antibiotics, and raising £4.3 million ($US 5.4 million) in seed funds.

https://sciencebusiness.technewslit.com/?p=45402

#News #Press #Science #Business #Biotechnology #Chemistry #Microbiology #GramNegative #Bacteria #AntiMicrobialResistance #Finance #SeedFunds

"Forgotten Antibiotic From Decades Past May Be a Superbug Killer"
#Medicine #Biology #Science! #Antibiotics #Streptothricin #GramNegative

https://www.sciencealert.com/forgotten-antibiotic-from-decades-past-may-be-a-superbug-killer

Cell envelope growth of #Gramnegative #bacteria proceeds independently of cell wall synthesis
Yuki Kitahara, Enno Oldewurtel, Lars Renner, Sven van Teeffelen and coworkers
https://www.embopress.org/doi/full/10.15252/embj.2022112168

Cell envelope growth of #Gramnegative #bacteria proceeds independently of cell wall synthesis
Yuki Kitahara, Enno Oldewurtel, Lars Renner, Sven van Teeffelen and coworkers
https://www.embopress.org/doi/full/10.15252/embj.2022112168

Vintage antibiotics? #Streptothricins were discovered in the 1940s to have v good #GramNegative #antibiotic activity. #Microbiology & structural studies reveal how they work, including interactions with the 30S ribosomal subunit #PLOSBiology https://plos.io/3o6BYsb

Vintage antibiotics? #Streptothricins were discovered in the 1940s to have v good #GramNegative #antibiotic activity. #Microbiology & structural studies reveal how they work, including interactions with the 30S ribosomal subunit #PLOSBiology https://plos.io/3o6BYsb