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#glycoproteins — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #glycoproteins, aggregated by home.social.

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  1. 🦴 Could a naturally occurring “biological lubricant” redefine how we treat joint health and gout?

    🔗 Lubricin’s Mucin Domain Has Strong Polyproline Type II Helical Character. Computational and Structural Biotechnology Journal (CSBJ). DOI: doi.org/10.34133/csbj.0021

    📚 CSBJ - A Science Partner Journal: spj.science.org/journal/csbj

    #StructuralBiology #ProteinScience #Biophysics #ComputationalBiology #Osteoarthritis #Glycoproteins #MolecularBiology

  2. New fluorescence method lights up a better glycan-cleaving enzyme

    Attached to many proteins are glycans—complex strings of sugars—that change how the whole unit functions. Removing them…
    #NewsBeep #News #Science #CA #Canada #directedevolution #enzymes #glycomics #glycoproteins #glycosidehydrolase #MassSpectrometry #mucin-type #n-glycans #o-glycans #Proteomics #sialylT-antigen #structuralbiology #Tools
    newsbeep.com/ca/164551/

  3. Comparative Characterization of #Bronchial and #Nasal #Mucus Reveals Key #Determinants of #Influenza A Virus #Inhibition biorxiv.org/cgi/content/short/

    The ability of mucus to neutralize influenza A virus varies with the anatomical origin of the #airway cultures and correlates with the abundance of #triglycerides and sialylated #glycoproteins and #glycolipids.

  4. #Adaptation potential of #H3N8 canine #influenza virus in #human respiratory #cells, Sci Rep.: nature.com/articles/s41598-024

    We found that CIV acquired high growth properties in these cells mainly through #mutations in surface #glycoproteins, such as hemagglutinin (#HA) and neuraminidase (#NA). Our reverse genetics approach revealed that HA2-K82E, HA2-R163K, and NA-S18L mutations were responsible for the increased growth of CIV in human cells.

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