#fnip1 — Public Fediverse posts

"… We don't yet know whether safely switching off FNIP1 with a drug would reproduce the benefits seen in people who naturally carry these mutations. The researchers note that complete disruption of the pathway can cause serious problems.

The study is another example of the power of human genetics to reveal what happens when nature accidentally switches off one component of our biology. Rare mutations can show researchers which biological pathways might be worth targeting.

These incredibly rare mutations, which might have been unfavorable for many millennia, are now favorable to the body," says Lotta. …"

Thanks @ScienceScholar

#fat #visceral #FNIP1 #genetics #science

"… We don't yet know whether safely switching off FNIP1 with a drug would reproduce the benefits seen in people who naturally carry these mutations. The researchers note that complete disruption of the pathway can cause serious problems.

The study is another example of the power of human genetics to reveal what happens when nature accidentally switches off one component of our biology. Rare mutations can show researchers which biological pathways might be worth targeting.

These incredibly rare mutations, which might have been unfavorable for many millennia, are now favorable to the body," says Lotta. …"

Thanks @ScienceScholar

#fat #visceral #FNIP1 #genetics #science