#evolgenpaper — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #evolgenpaper, aggregated by home.social.
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Our preprint describes how #EffectivePopulationSize affects #AminoAcid usage. https://www.biorxiv.org/content/10.1101/2023.02.01.526552v2. Within highly exchangeable pairs of amino acids, high Ne species are able to prefer #arginine over #lysine, and #valine over #isoleucine. This matches #thermophile preferences, as expected from theories of marginal protein stability at mutation-selection-drift balance. 1/6
@hanonmcshea #NearlyNeutralTheory #MolecularEvolution #EvolgenPaper -
Delighted to share our new Science #EvolgenPaper! https://www.science.org/doi/10.1126/science.abn3107
We introduce #TOGA, a #ComparativeGenomics method that combines the detection of orthologous genes with gene annotation. In plain words, TOGA can take advantage of a well-annotated #genome and transfer its annotations to a genome of a different species (e.g., from the human genome to that of a squirrel). 1/2