#escmidglobal2026 — Public Fediverse posts

Of note, TB helps here - turnaround time not THAT fast (still 16 days from positive culture to WGS guided treatment recommendations), but it's a slow disease. Not easily applicable to all other infections #TBSky #IDSky #ESCMIDGlobal2026 (2/3)

Quite impressive to see a new diagnostic intervention (whole genome sequencing for rifampicin-resistant TB) to be superior to SOC. Giving better drugs quicker works! Though note this was vs old standard of care for MDR-TB. (ie SOC now likely would do better anyway) #ESCMIDGlobal2026 #TBSky (1/3)

RE: https://bsky.app/profile/did:plc:4xb2h7na3qzshqu2yxtiylwj/post/3mjwgmuchfc24

SCOUT UTI study great. N=768 👍. Interesting observations: 👉 clearly nitro great 👉 pivm also great (held back vs ESBL, but not inferior) 👉 fosfo not great *even with 2 doses*. Were these the non-E coli? 👉 better clinical resolution if micro +ve. Some are not actually UTI? #ESCMIDGlobal2026 #UTISky

RE: https://bsky.app/profile/did:plc:4xb2h7na3qzshqu2yxtiylwj/post/3mjwfev2sxk24

UTI field on 🔥 - so much happening - case (re-)definitions, diagnosis & treatment #UTISky #ESCMIDGlobal2026

New(ish) diagnostics in UTI diagnosis Rapid culture in nano format - results in <1hr Promising for fast turnaround results - impact on clinical care? #UTIsky #ESCMIDGlobal2026

Interesting idea from @[email protected] data - using urine metabolomics (from bacteria) to predict risk of UTI recurrence. Needs validation and even if it validates, interesting to think what one could do with that information! #ESCMIDGlobal2026 #UTISky

The answer to previous question.... Check out Lactobacillus in healthy but also that oestrogen replacement makes rUTI group look like healthy. Question is whether the increased Lactobacillus are the mechanims through UTI prevention with oestrogen @[email protected] #UTISky #ESCMIDGlobal2026

RE: https://bsky.app/profile/did:plc:dmy36y7p2lwmdc54fjis4uez/post/3mjucjgme6k2z

Normal urine is not sterile! Urine microbiome being introduced by @[email protected] #ESCMIDGlobal2026 #UTISky

A post applicable way beyond just #ESCMIDGlobal2026! 👇 #MedSky #AcademicSky

RE: https://bsky.app/profile/did:plc:vcmyw2jthzh5tcbviee25zda/post/3mjsi3jblks2d

And an excellent summary. It's all go in the world of TB treatment! #ESCMIDGlobal2026 #TBSky #IDSky

RE: https://bsky.app/profile/did:plc:dmy36y7p2lwmdc54fjis4uez/post/3mjrsbtiov22v

Nice vision by Nicholas Paton for TB treatment in the future. 8 week oral treatment followed by long-acting injectable that could be antimicrobial +/- host-directed. Definitely a post to come back to in 5-10 years' time! #ESCMIDGlobal2026 #IDSky #TBSky

Recent nice paper @[email protected] looked at this: radiolgical changes (not culture) in asymptomatic contacts predictive of risk of TB disease development. PET-CT best but CXR not bad and feasible. @[email protected] www.thelancet.com/journals/lan... #IDSky #TBSky #ESCMIDGlobal2026 (2/2)

Excellent talk from Hanif Esmail on asymptomatic TB. Around half of M tuberculosis culture positive patients have no symptoms & probably contributes to transmission. Who should we offer treatment to? #TBSky #IDSky #ESCMIDGlobal2026 (1/2)

For those that don't know (included me!), Gremubamab binds specifically to the Pseudomonas aeruginosa PcrV protein and the Psl exopolysaccharide. Both are virulence factors used for adhesion and biofilm stability. Thanks @[email protected] ! #ESCMIDGlobal2026 #IDSky #ClinMicro

RE: https://bsky.app/profile/did:plc:jh6ykfvllrvxnubjpzazm2vb/post/3mjr55jvdxc2u