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#epitope — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #epitope, aggregated by home.social.

  1. #Epitope analysis methods can elucidate the basis of #antibody target specificity, but are often limited in resolution. This study presents DECODE, a high-throughput approach that provides single amino acid resolution for antibodies that recognize linear epitopes #PLOSBiology plos.io/40LPxxQ

  2. Fully #human single-domain #antibody targeting a highly conserved cryptic #epitope on the #Nipah virus G protein nature.com/articles/s41467-024

    The fully human single-domain antibody n425 aginst NiV targets a conserved cryptic epitope on G protein and inhibits membrane fusion by disrupting tetramerization. These insights advance neutralization mechanisms and effective countermeasure design.

  3. Pipeline release! nf-core/epitopeprediction v2.3.1 - v2.3.1 - Oesterberg - 2024-05-17!

    Please see the changelog: github.com/nf-core/epitopepred

    #epitope #epitope-prediction #mhc-binding-prediction #nfcore #openscience #nextflow #bioinformatics

  4. Our latest paper has now been published in #ImmunoInformatics! 🎉

    Predicting #TCR #epitope binding is extremely challenging. 🤯 We used #InterpretableAI techniques to explore how these prediction models work, to achieve a deeper understanding of TCR–epitope interactions and learn how these computational tools can be improved. 🕵️

    Publication: sciencedirect.com/science/arti