#engram — Public Fediverse posts

#DeepSeek, in collaboration with Peking University, introduced #Engram, a new training method that decouples #memory storage from computational processes. It may help ease memory constraints across AI infrastructure, potentially reducing sharp #DDR5 #DRAM price swings. https://www.techradar.com/pro/deepseek-may-have-found-a-way-to-solve-the-ram-crisis-by-eliminating-the-need-for-expensive-hbm-for-ai-inference-and-training-yes-the-very-reason-why-dram-prices-went-up-by-5x-in-10-weeks?AIagents.at #AIagent #AI #ML #NLP #LLM #GenAI

Postdoc (Jonas group “Nanophysiology” - ISTA)

Institute of Science and Technology Austria (ISTA)

See the full job description on jobRxiv: https://jobrxiv.org/job/institute-of-science-and-technology-austria-ista-27778-postdoc-jonas-group-nanophysiology-ista/?feed_id=97654

#Cellular_neuroscience #engram #neurophysiology #synaptic_plasticity #synaptic_transmis...
https://jobrxiv.org/job/institute-of-science-and-technology-austria-ista-27778-postdoc-jonas-group-nanophysiology-ista/?feed_id=97654

Postdoc (Jonas group “Nanophysiology” - ISTA)

Institute of Science and Technology Austria (ISTA)

See the full job description on jobRxiv: https://jobrxiv.org/job/institute-of-science-and-technology-austria-ista-27778-postdoc-jonas-group-nanophysiology-ista/?feed_id=97325

#Cellular_neuroscience #engram #neurophysiology #synaptic_plasticity #synaptic_transmis...
https://jobrxiv.org/job/institute-of-science-and-technology-austria-ista-27778-postdoc-jonas-group-nanophysiology-ista/?feed_id=97325

Postdoc (Jonas group “Nanophysiology” - ISTA)

Institute of Science and Technology Austria (ISTA)

See the full job description on jobRxiv: https://jobrxiv.org/job/institute-of-science-and-technology-austria-ista-27778-postdoc-jonas-group-nanophysiology-ista/?feed_id=97059

#Cellular_neuroscience #engram #neurophysiology #synaptic_plasticity #synaptic_transmis...
https://jobrxiv.org/job/institute-of-science-and-technology-austria-ista-27778-postdoc-jonas-group-nanophysiology-ista/?feed_id=97059

Postdoc (Jonas group “Nanophysiology” - ISTA)

Institute of Science and Technology Austria (ISTA)

See the full job description on jobRxiv: https://jobrxiv.org/job/institute-of-science-and-technology-austria-ista-27778-postdoc-jonas-group-nanophysiology-ista/?feed_id=96884

#Cellular_neuroscience #engram #neurophysiology #synaptic_plasticity #synaptic_transmis...
https://jobrxiv.org/job/institute-of-science-and-technology-austria-ista-27778-postdoc-jonas-group-nanophysiology-ista/?feed_id=96884

Postdoc (Jonas group “Nanophysiology” - ISTA)

Institute of Science and Technology Austria (ISTA)

See the full job description on jobRxiv: https://jobrxiv.org/job/institute-of-science-and-technology-austria-ista-27778-postdoc-jonas-group-nanophysiology-ista/?feed_id=96478

#Cellular_neuroscience #engram #neurophysiology #synaptic_plasticity #synaptic_transmis...
https://jobrxiv.org/job/institute-of-science-and-technology-austria-ista-27778-postdoc-jonas-group-nanophysiology-ista/?feed_id=96478

Postdoc (Jonas group “Nanophysiology” - ISTA)

Institute of Science and Technology Austria (ISTA)

See the full job description on jobRxiv: https://jobrxiv.org/job/institute-of-science-and-technology-austria-ista-27778-postdoc-jonas-group-nanophysiology-ista/?feed_id=96338

#Cellular_neuroscience #engram #neurophysiology #synaptic_plasticity #synaptic_transmis...
https://jobrxiv.org/job/institute-of-science-and-technology-austria-ista-27778-postdoc-jonas-group-nanophysiology-ista/?feed_id=96338

Postdoc (Jonas group “Nanophysiology” - ISTA)

Institute of Science and Technology Austria (ISTA)

See the full job description on jobRxiv: https://jobrxiv.org/job/institute-of-science-and-technology-austria-ista-27778-postdoc-jonas-group-nanophysiology-ista/?feed_id=95820

#Cellular_neuroscience #engram #neurophysiology #synaptic_plasticity #synaptic_transmis...
https://jobrxiv.org/job/institute-of-science-and-technology-austria-ista-27778-postdoc-jonas-group-nanophysiology-ista/?feed_id=95820

Postdoc (Jonas group “Nanophysiology” - ISTA)

Institute of Science and Technology Austria (ISTA)

See the full job description on jobRxiv: https://jobrxiv.org/job/institute-of-science-and-technology-austria-ista-27778-postdoc-jonas-group-nanophysiology-ista/?feed_id=95624

#Cellular_neuroscience #engram #neurophysiology #synaptic_plasticity #synaptic_transmis...
https://jobrxiv.org/job/institute-of-science-and-technology-austria-ista-27778-postdoc-jonas-group-nanophysiology-ista/?feed_id=95624

Postdoc (Jonas group “Nanophysiology” - ISTA)

Institute of Science and Technology Austria (ISTA)

See the full job description on jobRxiv: https://jobrxiv.org/job/institute-of-science-and-technology-austria-ista-27778-postdoc-jonas-group-nanophysiology-ista/?feed_id=95589

#Cellular_neuroscience #engram #neurophysiology #synaptic_plasticity #synaptic_transmis...
https://jobrxiv.org/job/institute-of-science-and-technology-austria-ista-27778-postdoc-jonas-group-nanophysiology-ista/?feed_id=95589

#FearGeneralization is a maladaptive response to harmless stimuli, characteristic of #PTSD. This study shows that competition between #engram & non-engram cells in the #DentateGyrus determines whether fear generalization occurs @PKU1898 #PLOSBiology https://plos.io/3LmxAgH

#AllaKatsnelson in @thetransmitter, on #SheenaJosselyn's work on #engrams.

I like #TheTransmitter for their accessible writing on #neuroscience. It's building bridges for interested people, without over-simplification.

»They seemed to be catching a glimpse of a real-time competitive mechanism in which the #neurons with the ramped up #CREB expression were primed to jump into an #engram. They had found what they were looking for.«

https://www.thetransmitter.org/memory/sheena-josselyn-and-memories-lost-found-and-created/

Spent some quality time with my Glove80 and Engram-based layout yesterday. I think this is, in fact, the end game. I’m still at 0 wpm on MonkeyType (having not used it or practiced for a couple of weeks), but it just feels really nice.

https://sunaku.github.io/moergo-glove80-keyboard.html

#glove80 #engram #sunaku #ergonomics #mechanicalkeyboards

New #preprint on “#Engram cell connectivity as a mechanism for #InformationEncoding and #memory function” by Clara Ortega-de San Luis et al.: https://doi.org/10.1101/2023.09.21.558774

#bioRxiv #neuroscience #EngramCells #Engrams

"we test the hypothesis that the specific synaptic wiring between engram cells is the substrate of information storage."

"Engram cell connectivity as a mechanism for information storage and memory function", by Ortega-de San Luis et al. 2023 https://www.biorxiv.org/content/10.1101/2023.09.21.558774v1

Figure 6 caught my attention: "Engram specific manipulation of PSD-95 modifies synaptic wiring and impairs extinction of a memory."

#engram #neuroscience #mouse #hippocampus #amygdala #PSD95

Neuroscientists successfully test theory that forgetting is actually a form of learning https://medicalxpress.com/news/2023-08-neuroscientists-successfully-theory.html

Adaptive expression of engrams by retroactive interference https://www.cell.com/cell-reports/fulltext/S2211-1247(23)01010-0

Highlights
• Retroactive interference causes forgetting by the competition of two memory engrams
• Forgotten engrams can be expressed or updated by reexposure to training cues
• Artificial reactivation of engram cells rescues interference-induced forgetting
• Interference is an active process that requires the activation of the suppressed engram

these findings indicate that retroactive interference modules engram expression in a manner that is both reversible and updatable. Inference may constitute a form of adaptive forgetting where, in everyday life, new perceptual and environmental inputs modulate the natural forgetting process.

#memory #engram #neuroscience #cognition

The good people at the Centre for Philosophy of Memory are holding a workshop on causation in memory.

Do memory traces exist? How would / do they work? What about reconstructing memories? What do we need in order to remember something?

Excellent speakers.

No registration required.

FREE access via Zoom!!!

https://phil-mem.org/events/2023-causation.php

#philosophy #PhilosophyOfMemory #Causation #MemoryTraces #UnversiteGrenobleAlps #Engram #Memory #OnlineWorkshop

How memories form across the #brain. Understanding how #neurons coordinate to create memories could one day point to interventions for disorders. In PNAS Journal Club: https://www.pnas.org/post/journal-club/memories-form-across-brain #neurobiology #engram #MemoryEnsemble #amygdala #microscopy

I've been having this constant discussion with all my favorite #engram people, on the nature of the ensemble and it's role in learning & memory.

The q remains the same: is the ensemble solely made of the neurons that get activated by any given stimulus, encoding relevant info? Or does it include the up/downstream connections of those neurons, which facilitate encoding/info relay?

Here some data!

Local memory allocation recruits memory ensembles across brain regions

https://www.sciencedirect.com/science/article/pii/S0896627322010728?dgcid=author

This is a super cool study, from a female-only team! Go #WomenInSTEM!

#EarlyLifeStress #Arc #SocialDefeat #DREADDs #Engram

Reactivation of early-life stress-sensitive neuronal ensembles contributes to lifelong stress hypersensitivity | bioRxiv
https://www.biorxiv.org/content/10.1101/2022.12.21.521303v1