#eg51 โ Public Fediverse posts
Live and recent posts from across the Fediverse tagged #eg51, aggregated by home.social.
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#Lineage-specific #pathogenicity, immune #evasion, and virological #features of #SARS-CoV-2 #BA286 / #JN1 and #EG51 / HK.3
Source: Nature Communications, AbstractSARS-CoV-2 JN.1 with an additional L455S mutation on spike when compared with its parental variant BA.2.86 has outcompeted all earlier variants to become the dominant circulating variant. Recent studies investigated the immune resistance of SARS-CoV-2 JN.1 but additional factors are speculated to contribute toโฆ
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Immunogenicity and #efficacy of #XBB15 rS #vaccine against the #EG51 #variant of #SARS-CoV-2 in Syrian #hamsters, J Virol.: https://journals.asm.org/doi/full/10.1128/jvi.00528-24?af=R
Thus, based on these study results, the protein-based XBB.1.5 vaccine is immunogenic and increased the breadth of protection against the Omicron EG.5.1 variant in the Syrian hamster model.
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Increased #pathogenicity {in animal models} and #transmission of #SarsCoV2 #Omicron #XBB19 #sublineage, including #HK3 and #EG51, BioRxIV, https://www.biorxiv.org/content/10.1101/2024.06.10.598324v1?rss=1
HK.3 and EG.5.1 exhibited greater pathogenicity than XBB.1.9.1 and BA.2 in H11-K18-hACE2 #hamsters. Our studies provide insight into the newly emerging #pathogens HK.3 and EG.5.1.
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Evaluating #Humoral #Immunity Elicited by #XBB15 Monovalent #COVID19 #Vaccine, Emerg Infect Dis.: https://wwwnc.cdc.gov/eid/article/30/6/24-0051_article
We report boosting of #IgG (2.1ร), #IgA (1.5ร), and total IgG/A/M (1.7ร) targeting the #spike receptor-binding domain and neutralizing titers against WA1 (2.2ร), XBB.1.5 (7.4ร), #EG51 (10.5ร), and #JN1 (4.7ร) variants.
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Virological characteristics of the #SARS-CoV-2 #BA286 #variant, Cell: https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(24)00005-2?rss=yes
โข BA.2.86 is more transmissible than the currently predominant #EG51
โข The sensitivity of BA.2.86 to #antiviral #drugs is comparable to that of EG.5.1
โข The #replication efficiency of BA.2.86 in vitro and in vivo is lower than that of EG.5.1
โข In hamsters, BA.2.86 is less #pathogenic than EG.5.1 and the parental BA.2 -
๐๐๐ง๐๐ฆ๐ง ๐จ๐ #COVID19
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๐ป6,117๐งฎ๐ง๐ผ๐ฝ ๐ฉ๐ฎ๐ฟ๐ถ๐ฎ๐ป๐๐
#JN1 #HV1 #EG51๐ฅ๐๐ผ๐๐ฝ๐ถ๐๐ฎ๐น ๐๐ฑ๐บ๐ถ๐๐๐ถ๐ผ๐ป๐ โ weekly
๐ป3,298๐ฏ๏ธ๐๐ฒ๐ฎ๐๐ต๐ โ weekly
๐บ301๐ฏ๏ธ๐ง๐ข๐ง๐๐ ๐๐ฒ๐ฎ๐๐ต๐
๐บ235,028โก๏ธhttp://PMP-Magazine.com/covid-19-today/
#COVIDisNotOver ๐ท
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Characterization of a #SARS-CoV-2 #EG51 clinical isolate in vitro and in vivo https://pubmed.ncbi.nlm.nih.gov/38103202/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=1lW0W_7uVpSIXMTzSBRwBwOZtB440RAJy7PjxSAyNIBZDMxMlI&fc=None&ff=20231217114409&v=2.18.0
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''Omicron #XBB15 #vaccine on days 8โ10 strongly + anti-S #IgG in all vaccinees & elicited potent neutralising responses vs previous & contemporary SARS-CoV-2 lineages, including #EG51 & #BA286. ... updated monovalent vaccine mRNA-1273.815 ... also increased nAbs titres against XBB sublineages in manufacturer preprint data. ...these data suggest that XBB.1.5-containing mRNA vax most likely increase protection vs COVID19 caused by currently circulating XBB subv. and emerging BA.2.86.''
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[Correspondence] Virus #isolation and #neutralisation of #SARS-CoV-2 #variants #BA286 and #EG51 https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00682-5/fulltext?rss=yes
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Promoting to @novid
Promising news about the upcoming COVID boosters!
H/T @erictopol
#COVID #COVIDVaccine #COVIDBooster #COVIDIsNotOver #WearAMask #XBB #BA286 #EG51 https://mstdn.social/@erictopol/111026999351394228
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''Data from July 31 to August 06, a rise in the incidence of several #VOIs has been observed, especially those belonging to #EG5 (a subvariant of #XBB192 with the additional Spike mutation: F456L), #XBB116 and #XBB1166 (with Spike mutation F456L). In particular, among sequenced viruses, #EG5 represented 32,4% (#EG51, 18,9%; #EG511,
13,5%); #XBB116 (18,9%) and XBB.1.16.6, 16,2%.'' -
Ein Update in meinem Blog #AllCoronavirusesAreBastards nach meinem Urlaub.
โช๏ธ Der Beginn der neuen #COVID19 Welle
โช๏ธ Die Varianten #EG51 und #FLip
โช๏ธ Ende der #LongCovid Ambulanz der #MedUniWien
โช๏ธ Was geschah mit dem Querdenker Reiner #Fuellmich?https://allcoronavirusesarebastards.substack.com/p/der-beginn-der-neuesten-covid-19
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The WHO is currently monitoring Erisโ spread but was hindered by a drop off in genomic sequencing and sharing of information between countries.
In the past month, only 25% of countries and territories have reported COVID-19 deaths to WHO and only 11% have reported hospitalisations and ICU admissions,โ Director-General Tedros Ghebreyesus said on Wednesday.
Professor Raina MacIntyre from the Kirby Institute at the University of NSW reminded Australians that even mild strains of the disease can do long-term damage.
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WHO declares โErisโ Covid strain a variant of interest as cases rise globally.
#COVID19 @WHO #Eris #EG5 #EG51 @auscovid19
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ยปโผ๏ธBad news. EG.5.1 escapes both XBB.1.5 and BA.5+XBB.1.5 breakthrough infection sera at unprecedented levels. Expect a big wave, and letโs hope cell-mediated immunity is not as bad.ยซ
https://twitter.com/dfocosi/status/1689347595993288705
Na geil, dann rettet uns der kommende XBB-Booster wohl auch kaum aus diesem Albtraum.
#EG51 #Covid -
With the new COVID Variant - Eris - on the rise, New York has recorded a 55% surge in the number of COVID cases reported. As the Eris or EG.5.1 variant becomes more common, the number of hospitalisations have also increased.
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Wo sind Infos zur Ausbreitung der neuen SARS-Cov-2-Varianten in Deutschland?
In den USA werden die Ansteckungen wieder mehr. -
New strain fuels COVID-19 case surge.
A new variant of COVID-19 dubbed Eris (EG.5.1) is spreading in nations as distant as India, the UK and US and in some areas has led to a 100% surge in cases.
The World Health Organsiation (WHO) began monitoring the EG.5.1. variant, derived from Omicron, on July 19.
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Promoting to @novid
Symptoms of a new COVID variantโฆcoming soon to a โitโs-just-really-bad-allergiesโ theater near you.
H/T @Brad
#COVIDisNotOver #WearAMask #COVID #Omicron #Eris #EG51 https://zeroes.ca/@Brad/110849235226299855
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Im neuesten Blogartikel berichtet @erictopol รผber die sich aufbauende neue #COVID19 Welle, die in erster Linie von der Subvariante EG.5.1 ausgeht. Dahinter folgt schon eine #FLip genannte Mutationskombi, die sowohl eine noch stรคrkere Bindung an den ACE2-Rezeptor als auch eine noch grรถรere Immunflucht mit sich bringt.
Der upgedatete #Booster wรคre umso wichtiger. Aber zumindest in den USA scheint sich der bis Oktober zu verzรถgern.
https://open.substack.com/pub/erictopol/p/the-virus-is-learning-new-tricks
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The World Health Organisation (WHO) sounds alarm as Covid-19 new variant โErisโ cases rise sharply in UK.
#COVID19UK @WHO #Eris #EG51 @DrTedros @auscovid19
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A new COVID variant known as EG.5.1 is spreading across the UK, according to the UK Health Security Agency (UKHSA) - and already makes up 1 in 7 new cases.
