@PLOSBiology has just published a collection of front-matter articles on #aging, under the theme "From cellular mechanisms to organismal physiology".
Geroscience aims to prevent disease and maintain good health into old age. Achieving these goals may require geroprotecting drugs, nutrition, exercise physiology, environmental exposure, probiotics, chronobiology, or social and behavioral science. The goal of this Collection is to help catalyze progress.
👵 Modig & Ebeling argue that most longevity gain comes from medical advances that allow survival with disease, rather than changes to the biology of aging, challenging how we study aging and #health
🧠 Mhatre & Moore discuss strategies to harness endogenous stem cell potential for resilience against cognitive aging
🥚 Jennifer Garrison argues that ovaries are systemic regulators of female physiology & the study of ovarian aging belongs at the center of geroscience
♀️ ♂️ Bérénice Benayoun & colleagues discuss that accounting for both sex and age is essential to advance personalized medicine
👶 🤱 👴 Alam, Partridge & Alic argue that the study of aging should include determinants of healthspan across the entire life course
👴 ➡️ 👶 Chiavellini & Sebastiano propose that ovarian biology is an ideal model to study rejuvenation
🦠 Liu, Silva Costa & Valenzano investigate #immunosenescence in age-associated #dysbiosis, exploring #microbiome collapse during aging and why stability fails
https://collections.plos.org/collection/aging-cellular-mechanisms-organismal-physiology/