#direwolf — Public Fediverse posts

Colossal Biosciences Is Making Jurassic Park Look Like a Pitch Deck

Dear Cherubs, Dallas has apparently decided extinction is just a product category. Colossal Biosciences is now a billionaire-level biotech spectacle, with the company saying its latest Series C brought total funding to $615 million and ABC News reporting a roster of celebrity backers that includes Tom Brady, Tiger Woods, Paris Hilton and Peter Jackson. Dallas Innovates also reported that the CIA’s venture arm, In-Q-Tel, invested in Colossal back in 2022.

The result is a company that sounds like it was brainstormed by a film studio, a venture fund and a very committed science teacher. Colossal says it is working on de-extinction projects tied to the woolly mammoth, dodo, thylacine and dire wolf, using gene editing, synthetic biology and related conservation tools. So no, this is not literally Jurassic Park; it is more like Jurassic Park after legal review and a lot of grant money.

THE TEA, BUT WITH MICROPIPETTES

In April, Reuters reported that Colossal announced three genetically engineered wolf pups and called them the world’s first successfully “de-extincted” animals, while outside experts were more cautious and described them as genetically modified gray wolves with added dire-wolf traits. ABC News said Colossal edited gray wolf cells at multiple sites and noted the two species are about 99.5% genetically identical, which is a very impressive number and also a reminder that biology is rude and complicated.

That is the key detail the movie version never pauses for: the company is not dusting off a frozen dinosaur and pressing play. It is using ancient DNA, gene editing and surrogate biology to create something that resembles an extinct species closely enough to trigger headlines, debates and a healthy amount of side-eye. The label “de-extincted” is doing a lot of heavy lifting here.

WHY THE MONEY FLOWS

The money makes more sense when you look at the technology stack. Dallas Innovates reported that In-Q-Tel said its interest in Colossal was “less about the mammoths and more about the capability,” while Colossal’s own materials say the work could scale CRISPR, synthetic biology, artificial wombs and genomic preservation platforms. In other words, the extinct-animal angle is the headline; the platform is the business.

Colossal has also built a pop-culture-friendly halo around the science. Its advisory board page lists Tom Brady and George R.R. Martin among its cultural advisors, which is exactly the kind of sentence that makes the internet stop scrolling for a second. That is the trick here: make de-extinction feel part science, part blockbuster, part meme, and suddenly the cap table looks almost inevitable.

The hot take is simple: this is not a cartoonish clone factory, and it is not pure hype either. It is a very expensive attempt to push gene editing, cloning-adjacent methods and reproductive tech into territory that could one day matter for conservation as much as spectacle. The dinosaurs are still fiction, but the lab bills are extremely real.

Sources list
ABC News — https://abcnews.go.com/US/dire-wolf-revived-biotech-companys-de-extinction-process/story?id=120558562
Reuters — https://www.reuters.com/science/us-company-resurrects-extinct-dire-wolf-or-some-version-it-2025-04-08/
Dallas Innovates — https://dallasinnovates.com/mammoth-interest-the-cia-invests-in-dallas-based-colossal-biosciences/
Colossal Biosciences — https://colossal.com/colossal-secures-200m-to-accelerate-de-extinction-and-genomic-innovation/
Colossal Biosciences — https://colossal.com/advisors/
Wikimedia Commons (Laboratory.jpg) — https://commons.wikimedia.org/wiki/File:Laboratory.jpg

I love how Coding agents allow me to implement the crazy ideas in my head! Checkout my TUI (Terminal UI) client for APRS. It now supports #digirig #mobilinkd and #direwolf. Check it out https://github.com/eusef/eusef-aprs-tui.

#amateurradio #emcomm #ham #hamradio #tui #terminalui #mapscii #

#packetradio using #digirig #aprs #direwolf #xastir #socat #packetradio #nixos #configurationdotnix #udev #ft818 #yaesuft818 #hamradio #resilientcommunication #Notfallkommunikation detailed setup video --->
https://youtu.be/smrTgJLs9Hg?si=i-F-vbtN7xKqZQTA
[ background info also under
https://themodernham.com/packet-radio-101-the-ultimate-guide/ (slow link)
https://youtu.be/V0FAzMIsxMg?si=vnqJyVgwbIoq-Gnm ]

#packetradio using #digirig #aprs #direwolf #xastir #socat #packetradio #nixos #configurationdotnix #udev #ft818 #yaesuft818 #hamradio #resilientcommunication #Notfallkommunikation detailed setup video --->
https://youtu.be/smrTgJLs9Hg?si=i-F-vbtN7xKqZQTA
[ background info also under
https://themodernham.com/packet-radio-101-the-ultimate-guide/ (slow link)
https://youtu.be/V0FAzMIsxMg?si=vnqJyVgwbIoq-Gnm ]

#packetradio using #digirig #aprs #direwolf #xastir #socat #packetradio #nixos #configurationdotnix #udev #ft818 #yaesuft818 #hamradio #resilientcommunication #Notfallkommunikation detailed setup video --->
https://youtu.be/smrTgJLs9Hg?si=i-F-vbtN7xKqZQTA
[ background info also under
https://themodernham.com/packet-radio-101-the-ultimate-guide/ (slow link)
https://youtu.be/V0FAzMIsxMg?si=vnqJyVgwbIoq-Gnm ]

#packetradio using #digirig #aprs #direwolf #xastir #socat #packetradio #nixos #configurationdotnix #udev #ft818 #yaesuft818 #hamradio #resilientcommunication #Notfallkommunikation detailed setup video --->
https://youtu.be/smrTgJLs9Hg?si=i-F-vbtN7xKqZQTA
[ background info also under
https://themodernham.com/packet-radio-101-the-ultimate-guide/ (slow link)
https://youtu.be/V0FAzMIsxMg?si=vnqJyVgwbIoq-Gnm ]

#packetradio using #digirig #aprs #direwolf #xastir #socat #packetradio #nixos #configurationdotnix #udev #ft818 #yaesuft818 #hamradio #resilientcommunication #Notfallkommunikation detailed setup video --->
https://youtu.be/smrTgJLs9Hg?si=i-F-vbtN7xKqZQTA
[ background info also under
https://themodernham.com/packet-radio-101-the-ultimate-guide/ (slow link)
https://youtu.be/V0FAzMIsxMg?si=vnqJyVgwbIoq-Gnm ]

https://youtu.be/Zu87ZLwZXdA?si=8ZxzrLWhlodItrLT #Audio #packet mediated #transmission of text data #messaging between two #linux #mint #thinkpad #x230 computers using #direwolf #ax25 #ax_25
and the loudspeaker of one to send to the microphone of the other at 300 #baud to explain the #audio building blocks of a #packetradio system. #netrom

https://youtu.be/Zu87ZLwZXdA?si=8ZxzrLWhlodItrLT #Audio #packet mediated #transmission of text data #messaging between two #linux #mint #thinkpad #x230 computers using #direwolf #ax25 #ax_25
and the loudspeaker of one to send to the microphone of the other at 300 #baud to explain the #audio building blocks of a #packetradio system. #netrom

https://youtu.be/Zu87ZLwZXdA?si=8ZxzrLWhlodItrLT #Audio #packet mediated #transmission of text data #messaging between two #linux #mint #thinkpad #x230 computers using #direwolf #ax25 #ax_25
and the loudspeaker of one to send to the microphone of the other at 300 #baud to explain the #audio building blocks of a #packetradio system. #netrom

https://youtu.be/Zu87ZLwZXdA?si=8ZxzrLWhlodItrLT #Audio #packet mediated #transmission of text data #messaging between two #linux #mint #thinkpad #x230 computers using #direwolf #ax25 #ax_25
and the loudspeaker of one to send to the microphone of the other at 300 #baud to explain the #audio building blocks of a #packetradio system. #netrom

https://youtu.be/Zu87ZLwZXdA?si=8ZxzrLWhlodItrLT #Audio #packet mediated #transmission of text data #messaging between two #linux #mint #thinkpad #x230 computers using #direwolf #ax25 #ax_25
and the loudspeaker of one to send to the microphone of the other at 300 #baud to explain the #audio building blocks of a #packetradio system. #netrom

Szyfrowanie danych, usuwanie backupów, zacieranie śladów… analiza ransomware Dire Wolf

Dire Wolf jest nową grupą przestępczą, której aktywność zaobserwowano w maju br. Pierwszymi ofiarami cyberprzestępców były firmy z sektora technologicznego, finansowego oraz budownictwa działające we Włoszech, Tajlandii, Australii oraz Indii. Działania cyberprzestępców ukierunkowane są głównie na zysk finansowy. W celu zwiększenia szansy na uzyskanie okupu, wykorzystują technikę double extortion, grożąc...

#Teksty #Chacha20 #Curbe25519 #Direwolf #DoubleExtortion #Ransomware

https://sekurak.pl/szyfrowanie-danych-usuwanie-backupow-zacieranie-sladow-analiza-ransomware-dire-wolf/

Szyfrowanie danych, usuwanie backupów, zacieranie śladów… analiza ransomware Dire Wolf

Dire Wolf jest nową grupą przestępczą, której aktywność zaobserwowano w maju br. Pierwszymi ofiarami cyberprzestępców były firmy z sektora technologicznego, finansowego oraz budownictwa działające we Włoszech, Tajlandii, Australii oraz Indii. Działania cyberprzestępców ukierunkowane są głównie na zysk finansowy. W celu zwiększenia szansy na uzyskanie okupu, wykorzystują technikę double extortion, grożąc...

#Teksty #Chacha20 #Curbe25519 #Direwolf #DoubleExtortion #Ransomware

https://sekurak.pl/szyfrowanie-danych-usuwanie-backupow-zacieranie-sladow-analiza-ransomware-dire-wolf/

Szyfrowanie danych, usuwanie backupów, zacieranie śladów… analiza ransomware Dire Wolf

Dire Wolf jest nową grupą przestępczą, której aktywność zaobserwowano w maju br. Pierwszymi ofiarami cyberprzestępców były firmy z sektora technologicznego, finansowego oraz budownictwa działające we Włoszech, Tajlandii, Australii oraz Indii. Działania cyberprzestępców ukierunkowane są głównie na zysk finansowy. W celu zwiększenia szansy na uzyskanie okupu, wykorzystują technikę double extortion, grożąc...

#Teksty #Chacha20 #Curbe25519 #Direwolf #DoubleExtortion #Ransomware

https://sekurak.pl/szyfrowanie-danych-usuwanie-backupow-zacieranie-sladow-analiza-ransomware-dire-wolf/

Szyfrowanie danych, usuwanie backupów, zacieranie śladów… analiza ransomware Dire Wolf

Dire Wolf jest nową grupą przestępczą, której aktywność zaobserwowano w maju br. Pierwszymi ofiarami cyberprzestępców były firmy z sektora technologicznego, finansowego oraz budownictwa działające we Włoszech, Tajlandii, Australii oraz Indii. Działania cyberprzestępców ukierunkowane są głównie na zysk finansowy. W celu zwiększenia szansy na uzyskanie okupu, wykorzystują technikę double extortion, grożąc...

#Teksty #Chacha20 #Curbe25519 #Direwolf #DoubleExtortion #Ransomware

https://sekurak.pl/szyfrowanie-danych-usuwanie-backupow-zacieranie-sladow-analiza-ransomware-dire-wolf/

Szyfrowanie danych, usuwanie backupów, zacieranie śladów… analiza ransomware Dire Wolf

Dire Wolf jest nową grupą przestępczą, której aktywność zaobserwowano w maju br. Pierwszymi ofiarami cyberprzestępców były firmy z sektora technologicznego, finansowego oraz budownictwa działające we Włoszech, Tajlandii, Australii oraz Indii. Działania cyberprzestępców ukierunkowane są głównie na zysk finansowy. W celu zwiększenia szansy na uzyskanie okupu, wykorzystują technikę double extortion, grożąc...

#Teksty #Chacha20 #Curbe25519 #Direwolf #DoubleExtortion #Ransomware

https://sekurak.pl/szyfrowanie-danych-usuwanie-backupow-zacieranie-sladow-analiza-ransomware-dire-wolf/

Where are my #macos #HamRadio #APRS #direwolf #digirig folks at?

So, my digirig works fine on macos if I just hamlib it. Like, I can rigctl, toggle the ptt, everything works just fine.

But, for whatever reason, direwolf _refuses_ to work.

I see it, like, flash the ptt once the first time I try to Tx, but nothing comes out, and then the ptt doesn't even trigger with subsequent attempted transmissions. The direwolf console registers that it Tx'd packets, and there are no error messages.

I've even tried running the digirig as a rigctld server locally. Same deal; other programs can trigger ptt for an arbitrary amount of time, but direwolf configured to use it still just flashes the first packet.

I don't have this issue on Linux, and I don't _think_ I have this problem when I use vox on a baofeng (I need to try again to verify).

https://www.europesays.com/uk/15911/ What does the dire wolf ‘de-extinction’ mean for bringing back Tasmanian tigers? #cloning #DeExtincting #DireWolf #DireWolves #DNA #ExtinctSpecies #Genes #Genetics #GenomicSequencing #Science #TasmanianTiger #Thylacine #UK #UnitedKingdom #What'sATasmanianTiger? #wildlife

#deExtinction: "The American company #Colossal changed only 14 genes to produce its cute "#direwolf" puppies. Curiously, all 14 are genes with effects on the appearance of animals, being linked to the colour, thickness and length of the fur and the size of the animals.

Is #resurrecting a species now just #cosplaying an extinct animal with a current species? To top it off, George R.R. Martin himself - yes, the author of #GameofThrones - signs the scientific article as well. And he is an investor in the company. He compared the feat to a form of "magic". Only if it's to magically fatten his bank account even more."

https://www1.folha.uol.com.br/colunas/reinaldojoselopes/2025/04/notas-sobre-a-pantomima-do-lobo-gigante.shtml

Scientists Claim To Have Brought Back Dire Wolves #colossalbiosciences #direwolf #direwolves #news #randomasitgets #woollymammoth

https://www.lowyat.net/2025/347312/scientists-claim-to-have-brought-back-dire-wolves/

My mobile APRS Digipeter doesn’t look suspicious at all… once up and running it pulls 0.11 Amps. With that 4.5Amp battery it should last 36 hours at 90% efficiency give or take. I can’t imagine trying to take this on a plane! #bioenno #aprs #digipeter #digirig #amateurradio #hamradio #packetradio #direwolf #photo

I want to try using #direwolf with #il2p on #hf soon, for #aprs & other #packetradio things. How well will it work with my #hermeslite2 #qrp radio...
Are you interested? 😄