#cytoskeleton — Public Fediverse posts

Study explains how environmental acidity destabilizes internal cellular traffic https://www.byteseu.com/2054442/ #Actin #Cancer #Cell #CellularTraffic #Cytoskeleton #diabetes #environment #GolgiApparatus #neuroscience #pH #Protein #Research #stress #Tumor

📰 "Hydroxychloroquine alters the cytoskeleton to impair cell migration"
https://www.biorxiv.org/content/10.64898/2026.05.16.725640v1?rss=1 #CellMigration #Cytoskeleton #Cell

📰 "Hydroxychloroquine alters the cytoskeleton to impair cell migration"
https://www.biorxiv.org/content/10.64898/2026.05.16.725640v1?rss=1 #CellMigration #Cytoskeleton #Cell

So far we heard from Marija Zanic who talked about SSNA1, a sensor for microtubule damage and microtubule stabiliser, that increases their rigidity and protects against breakage.

Next, Varun Ramaswamy described how he tackled the difficult problem of determining the structure of full length HSET motor.

#Biophysics #Cytoskeleton

Meharry Medical College student Mudiare Ikoba highlights a publication in the Journal of Cell Biology from SBGrid member Antonina Roll-Mecak and colleagues in which the authors analyze the structure of the RPGR-TTLL5 complex to shed light on the pathomechanism of retititis pigmentosa.

Read more here: https://medium.com/sbgrid-community-news/how-proteins-work-together-to-support-our-vision-e4e1a30a6850

#SBGrid #Cytoskeleton #Retina

Meharry Medical College student Mudiare Ikoba highlights a publication in the Journal of Cell Biology from SBGrid member Antonina Roll-Mecak and colleagues in which the authors analyze the structure of the RPGR-TTLL5 complex to shed light on the pathomechanism of retititis pigmentosa.

Read more here: https://medium.com/sbgrid-community-news/how-proteins-work-together-to-support-our-vision-e4e1a30a6850

#SBGrid #Cytoskeleton #Retina

Meharry Medical College student Mudiare Ikoba highlights a publication in the Journal of Cell Biology from SBGrid member Antonina Roll-Mecak and colleagues in which the authors analyze the structure of the RPGR-TTLL5 complex to shed light on the pathomechanism of retititis pigmentosa.

Read more here: https://medium.com/sbgrid-community-news/how-proteins-work-together-to-support-our-vision-e4e1a30a6850

#SBGrid #Cytoskeleton #Retina

https://www.europesays.com/ie/460215/ Cells filter physical forces based on duration to detect disease #Bioengineering #Bladder #Breathing #cancer #Cell #Cytoskeleton #Éire #fibrosis #Heart #IE #Ireland #Lungs #Research #Science #Students #Technology #Wound #WoundHealing

📰 "Drak is a potential binding partner of Drosophila Filamin"
https://doi.org/doi:10.1242/bio.062185
https://pubmed.ncbi.nlm.nih.gov/41913654/
#Mechanosensing #Cytoskeleton

📰 "Drak is a potential binding partner of Drosophila Filamin"
https://doi.org/doi:10.1242/bio.062185
https://pubmed.ncbi.nlm.nih.gov/41913654/
#Mechanosensing #Cytoskeleton

📰 "Loss of Sun2 ablates nuclear mechanosensing-driven extracellular matrix production and mitigates lung fibrosis"
https://doi.org/doi:10.64898/2026.03.18.712778
https://pubmed.ncbi.nlm.nih.gov/41889916/
#Mechanosensing #Extracellular #Cytoskeleton #Mechanical

📰 "Loss of Sun2 ablates nuclear mechanosensing-driven extracellular matrix production and mitigates lung fibrosis"
https://doi.org/doi:10.64898/2026.03.18.712778
https://pubmed.ncbi.nlm.nih.gov/41889916/
#Mechanosensing #Extracellular #Cytoskeleton #Mechanical

Today's talk will be:

Isaac Wong (Dunn School, Oxford)

Mechanical Principles of Centrosome Assembly and Function

CTU 0.08/09 at 13.05

#CellBiology #cytoskeleton

📰 "Loss of Sun2 ablates nuclear mechanosensing-driven extracellular matrix production and mitigates lung fibrosis"
https://www.biorxiv.org/content/10.64898/2026.03.18.712778v1?rss=1 #Mechanosensing #Extracellular #Cytoskeleton #Mechanical

📰 "Loss of Sun2 ablates nuclear mechanosensing-driven extracellular matrix production and mitigates lung fibrosis"
https://www.biorxiv.org/content/10.64898/2026.03.18.712778v1?rss=1 #Mechanosensing #Extracellular #Cytoskeleton #Mechanical

📰 "Disruption of nuclear-cytoskeletal connection impairs epithelial cell mechanosensing and collective migration"
https://doi.org/doi:10.1016/j.bpj.2026.03.030
https://pubmed.ncbi.nlm.nih.gov/41832602/
#Mechanosensing #CellMigration #Cytoskeleton #Cytoskeletal

📰 "Disruption of nuclear-cytoskeletal connection impairs epithelial cell mechanosensing and collective migration"
https://doi.org/doi:10.1016/j.bpj.2026.03.030
https://pubmed.ncbi.nlm.nih.gov/41832602/
#Mechanosensing #CellMigration #Cytoskeleton #Cytoskeletal

🚨 NEW PAPER 🚨

Vishakha and colleagues in the Cross group show that ATPγS causes single kinesin molecules to pause under load in an Await-Isomerisation (AI) state that leaks hand-over-hand backsteps.

"ATPγS substantially defeats the biasing mechanism for kinesin steps”

https://www.nature.com/articles/s41467-026-69573-z

#biophysics #cytoskeleton #cellbiology #MotorHeads

🚨 NEW PAPER 🚨

Vishakha and colleagues in the Cross group show that ATPγS causes single kinesin molecules to pause under load in an Await-Isomerisation (AI) state that leaks hand-over-hand backsteps.

"ATPγS substantially defeats the biasing mechanism for kinesin steps”

https://www.nature.com/articles/s41467-026-69573-z

#biophysics #cytoskeleton #cellbiology #MotorHeads

🚨 NEW PAPER 🚨

Vishakha and colleagues in the Cross group show that ATPγS causes single kinesin molecules to pause under load in an Await-Isomerisation (AI) state that leaks hand-over-hand backsteps.

"ATPγS substantially defeats the biasing mechanism for kinesin steps”

https://www.nature.com/articles/s41467-026-69573-z

#biophysics #cytoskeleton #cellbiology #MotorHeads

🚨 NEW PAPER 🚨

Vishakha and colleagues in the Cross group show that ATPγS causes single kinesin molecules to pause under load in an Await-Isomerisation (AI) state that leaks hand-over-hand backsteps.

"ATPγS substantially defeats the biasing mechanism for kinesin steps”

https://www.nature.com/articles/s41467-026-69573-z

#biophysics #cytoskeleton #cellbiology #MotorHeads

https://www.europesays.com/ie/305585/ Physical behavior reveals aggressive cancer cells in a simple new approach #Actin #cancer #Cell #CellNucleus #Cytoskeleton #Diagnostic #Éire #Genes #Genetic #Health #IE #Ireland #Laboratory #Metastasis #Nanoscience #Nanotechnology #Research #Technology #Tumor

Calling all #MotorsInQuarantine fans: Please join us for 1.5 days of science on motors and the cytoskeleton as we celebrate the career of Rob Cross. More info and sign-up here:

https://tinyurl.com/mechanochemistry

#CellBiology #Cytoskeleton #MotorHeads #Cytoskeleton

Calling all #MotorsInQuarantine fans: Please join us for 1.5 days of science on motors and the cytoskeleton as we celebrate the career of Rob Cross. More info and sign-up here:

https://tinyurl.com/mechanochemistry

#CellBiology #Cytoskeleton #MotorHeads #Cytoskeleton

Calling all #MotorsInQuarantine fans: Please join us for 1.5 days of science on motors and the cytoskeleton as we celebrate the career of Rob Cross. More info and sign-up here:

https://tinyurl.com/mechanochemistry

#CellBiology #Cytoskeleton #MotorHeads #Cytoskeleton

Calling all #MotorsInQuarantine fans: Please join us for 1.5 days of science on motors and the cytoskeleton as we celebrate the career of Rob Cross. More info and sign-up here:

https://tinyurl.com/mechanochemistry

#CellBiology #Cytoskeleton #MotorHeads #Cytoskeleton

Calling all #MotorsInQuarantine fans: Please join us for 1.5 days of science on motors and the cytoskeleton as we celebrate the career of Rob Cross. More info and sign-up here:

https://tinyurl.com/mechanochemistry

#CellBiology #Cytoskeleton #MotorHeads #Cytoskeleton

Axons and dendrites are fundamentally different. An example from #Drosophila:

"axons and dendrites can accumulate different microtubule-binding proteins; protein synthesis machinery is concentrated in the cell body; pre- and post-synaptic sites localize to distinct regions of the neuron; and specializations similar to the initial segment are present. In addition, we track EB1-GFP dynamics and determine microtubules in axons and dendrites have opposite polarity."

"Polarity and intracellular compartmentalization of Drosophila neurons", Rolls et al. 2007
https://link.springer.com/article/10.1186/1749-8104-2-7

To collapse axons and dendrites into point neurons in a simulation of neural circuits is, at this point, malpractice.

#neuroscience #cytoskeleton #axons #dendrites

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)
UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/

#biologicalphysics #biophysics #cellbiology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?fsp_sid=5562

"Charting the landscape of cytoskeletal diversity in microbial eukaryotes", Mikus et al. 2025 (Dudin lab)
https://www.cell.com/cell/fulltext/S0092-8674(25)01127-4

CC @davi

#CellBiology #cytoskeleton #ExM

Anne says: The motors are out of quarantine and we plan to assemble in person on 8th May 2026 at University of Warwick Campus for a fun day on motors and the filaments they walk along. Livestream is planned too. More details on registration, travel bursaries etc. will be revealed soon.

#biophysics #cytoskeleton #motorheads

Anne says: The motors are out of quarantine and we plan to assemble in person on 8th May 2026 at University of Warwick Campus for a fun day on motors and the filaments they walk along. Livestream is planned too. More details on registration, travel bursaries etc. will be revealed soon.

#biophysics #cytoskeleton #motorheads

Anne says: The motors are out of quarantine and we plan to assemble in person on 8th May 2026 at University of Warwick Campus for a fun day on motors and the filaments they walk along. Livestream is planned too. More details on registration, travel bursaries etc. will be revealed soon.

#biophysics #cytoskeleton #motorheads

Anne says: The motors are out of quarantine and we plan to assemble in person on 8th May 2026 at University of Warwick Campus for a fun day on motors and the filaments they walk along. Livestream is planned too. More details on registration, travel bursaries etc. will be revealed soon.

#biophysics #cytoskeleton #motorheads

📰 "Drak is a potential mechanotransduction partner of Filamin"
https://www.biorxiv.org/content/10.1101/2025.10.24.684132v1?rss=1 #Mechanotransduction #Mechanosensing #Cytoskeleton

@sellathechemist @compoundchem phallotoxins like phalloidin, also fascinating. Used extensively in #CellBiology research to label #Actin #Cytoskeleton, but i don't really know the route of toxicity in animals.

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)
UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/

#biologicalphysics #biophysics #cellbiology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?fsp_sid=3812

📰 "Vimentin networks at high strains"
https://www.biorxiv.org/content/10.1101/2025.10.06.680657v1?rss=1 #Cytoskeleton #Vimentin #Force

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)
UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/

#biologicalphysics #biophysics #cellbiology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?fsp_sid=2699

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)
UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/

#biologicalphysics #biophysics #cellbiology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?fsp_sid=1628

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)
UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/

#biologicalphysics #biophysics #cellbiology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?fsp_sid=501

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97647

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97640

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97640

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97640

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97640

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97640

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97640

Postdoc in the Hueschen Lab, UCSD (biophysics, cell biology, parasites)

UC San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97640

#biological_physics #biophysics #cell_biology #cytoskeleton #parasites #ScienceJobs #hiring #research
https://jobrxiv.org/job/uc-san-diego-27778-postdoc-in-the-hueschen-lab-ucsd-biophysics-cell-biology-parasites/?feed_id=97640