#computationalmodel — Public Fediverse posts

⚡ Schizophrenia • Depression • PTSD • Bipolar • Autism • Epilepsy • Alzheimer’s • Addiction

All may share one root cause: collapse of the hippocampal Excitability Margin.
When ΔVmargin shrinks from 20 mV → ≤ 5 mV, ordinary oscillations trigger involuntary emotional replays → vicious loops.

🧠 One mechanism, many disorders.

#Neuroscience #Psychiatry #BrainHealth #ComputationalModel #MentalHealthResearch

New #fMRI + #ComputationalModel #NeuroPaper by #SummerfieldLab:

Goal-seeking compresses neural codes for space in the human hippocampus and orbitofrontal cortex

4- More recently: thread on our review of #SplitterCells (a subset of #PlaceCells) where we try to summarize and make sense of many studies, asking if they might support decision-making, or which type of #ComputationalModel might support their firing:
https://elduvelle.github.io/ElDuvelle/status/1556036545223745538/

The associated paper:
Temporal context and latent state inference in the hippocampal splitter signal

It seems like a combination of two types of models - Latent State models and Temporal Context models - might best suit the hippocampal Splitter Signal.. but (IMO) it doesn't look like Splitter cells are really doing anything for actual, immediate decision-making.

4/x

#arxivfeed

"Implicit Transfer Operator Learning: Multiple Time-Resolution Surrogates for Molecular Dynamics"
https://arxiv.org/abs/2305.18046

#MolecularDynamics #ComputationalModel #SurrogateModel #TimeScale #Simulation #DiffusionModel

#NeuroPreprint #Replay #Hippocampus #ComputationalModel
Constructing future behaviour in the hippocampal formation through composition and replays

It might be fun to develop an agent-based #ComputationalModel of social #network dynamics to #model the #TwitterMigration

The parameters of the model could then be updated on the fly via #Bayesian inference 😎

Or maybe, the current situation could be used to test critical predictions derived from existing models...

#arxivfeed

"Implicit Transfer Operator Learning: Multiple Time-Resolution Surrogates for Molecular Dynamics"
https://arxiv.org/abs/2305.18046

#MolecularDynamics #ComputationalModel #SurrogateModel #TimeScale #Simulation #DiffusionModel

#arxivfeed

"Implicit Transfer Operator Learning: Multiple Time-Resolution Surrogates for Molecular Dynamics"
https://arxiv.org/abs/2305.18046

#MolecularDynamics #ComputationalModel #SurrogateModel #TimeScale #Simulation #DiffusionModel

#arxivfeed

"Implicit Transfer Operator Learning: Multiple Time-Resolution Surrogates for Molecular Dynamics"
https://arxiv.org/abs/2305.18046

#MolecularDynamics #ComputationalModel #SurrogateModel #TimeScale #Simulation #DiffusionModel

#arxivfeed

"Implicit Transfer Operator Learning: Multiple Time-Resolution Surrogates for Molecular Dynamics"
https://arxiv.org/abs/2305.18046

#MolecularDynamics #ComputationalModel #SurrogateModel #TimeScale #Simulation #DiffusionModel