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#computational-biology — Public Fediverse posts

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  1. 🤖 What if protein classification errors begin before the AI even starts learning?

    🔗 Vertex Assignment for Frequency Chaos Game Representation of Proteins Affects Classification Performance. Computational and Structural Biotechnology Journal (CSBJ). DOI: doi.org/10.34133/csbj.0225

    📚 CSBJ - A Science Partner Journal: spj.science.org/journal/csbj

    #Bioinformatics #MachineLearning #DeepLearning #Proteomics #ComputationalBiology #ProteinScience #ArtificialIntelligence

  2. 🤖 What if protein classification errors begin before the AI even starts learning?

    🔗 Vertex Assignment for Frequency Chaos Game Representation of Proteins Affects Classification Performance. Computational and Structural Biotechnology Journal (CSBJ). DOI: doi.org/10.34133/csbj.0225

    📚 CSBJ - A Science Partner Journal: spj.science.org/journal/csbj

    #Bioinformatics #MachineLearning #DeepLearning #Proteomics #ComputationalBiology #ProteinScience #ArtificialIntelligence

  3. Researchers have mapped the molecular activity underlying hypertrophic cardiomyopathy (HCM), a disease causing thickening and stiffening of the heart muscle.
    #Cardiology #Genetics #MolecularBiology #ComputationalBiology #sflorg
    sflorg.com/2026/09/med09182601

  4. Researchers have mapped the molecular activity underlying hypertrophic cardiomyopathy (HCM), a disease causing thickening and stiffening of the heart muscle.
    #Cardiology #Genetics #MolecularBiology #ComputationalBiology #sflorg
    sflorg.com/2026/09/med09182601

  5. Researchers have mapped the molecular activity underlying hypertrophic cardiomyopathy (HCM), a disease causing thickening and stiffening of the heart muscle.
    #Cardiology #Genetics #MolecularBiology #ComputationalBiology #sflorg
    sflorg.com/2026/09/med09182601

  6. Researchers have mapped the molecular activity underlying hypertrophic cardiomyopathy (HCM), a disease causing thickening and stiffening of the heart muscle.
    #Cardiology #Genetics #MolecularBiology #ComputationalBiology #sflorg
    sflorg.com/2026/09/med09182601

  7. Researchers have mapped the molecular activity underlying hypertrophic cardiomyopathy (HCM), a disease causing thickening and stiffening of the heart muscle.
    #Cardiology #Genetics #MolecularBiology #ComputationalBiology #sflorg
    sflorg.com/2026/09/med09182601

  8. Delphy is a web-based software application designed to rapidly assemble phylogenetic trees, mapping the evolution and spread of viral variants from genomic sequence data in near-real time.
    #ComputationalBiology #Epidemiology #Genomics #Virology #sflorg
    sflorg.com/2026/09/cobi0916260

  9. Delphy is a web-based software application designed to rapidly assemble phylogenetic trees, mapping the evolution and spread of viral variants from genomic sequence data in near-real time.
    #ComputationalBiology #Epidemiology #Genomics #Virology #sflorg
    sflorg.com/2026/09/cobi0916260

  10. Delphy is a web-based software application designed to rapidly assemble phylogenetic trees, mapping the evolution and spread of viral variants from genomic sequence data in near-real time.
    #ComputationalBiology #Epidemiology #Genomics #Virology #sflorg
    sflorg.com/2026/09/cobi0916260

  11. Delphy is a web-based software application designed to rapidly assemble phylogenetic trees, mapping the evolution and spread of viral variants from genomic sequence data in near-real time.
    #ComputationalBiology #Epidemiology #Genomics #Virology #sflorg
    sflorg.com/2026/09/cobi0916260

  12. Delphy is a web-based software application designed to rapidly assemble phylogenetic trees, mapping the evolution and spread of viral variants from genomic sequence data in near-real time.
    #ComputationalBiology #Epidemiology #Genomics #Virology #sflorg
    sflorg.com/2026/09/cobi0916260

  13. If you are interested in how AI can support the development of scientific software, I invite you to attend my workshop at the 71st Annual Meeting of the Biophysical Society in Philadelphia.

    On February 23, 2027, at 7:30 PM, I will present “Developing Scientific Software with AI: Opportunities, Practices, and Pitfalls for Biophysicists.”

    I am grateful for the invitation and look forward to the discussion.

    See you at #BPS2027 #Biophysics #AI #ComputationalBiology

  14. If you are interested in how AI can support the development of scientific software, I invite you to attend my workshop at the 71st Annual Meeting of the Biophysical Society in Philadelphia.

    On February 23, 2027, at 7:30 PM, I will present “Developing Scientific Software with AI: Opportunities, Practices, and Pitfalls for Biophysicists.”

    I am grateful for the invitation and look forward to the discussion.

    See you at #BPS2027 #Biophysics #AI #ComputationalBiology

  15. If you are interested in how AI can support the development of scientific software, I invite you to attend my workshop at the 71st Annual Meeting of the Biophysical Society in Philadelphia.

    On February 23, 2027, at 7:30 PM, I will present “Developing Scientific Software with AI: Opportunities, Practices, and Pitfalls for Biophysicists.”

    I am grateful for the invitation and look forward to the discussion.

    See you at #BPS2027 #Biophysics #AI #ComputationalBiology

  16. If you are interested in how AI can support the development of scientific software, I invite you to attend my workshop at the 71st Annual Meeting of the Biophysical Society in Philadelphia.

    On February 23, 2027, at 7:30 PM, I will present “Developing Scientific Software with AI: Opportunities, Practices, and Pitfalls for Biophysicists.”

    I am grateful for the invitation and look forward to the discussion.

    See you at #BPS2027 #Biophysics #AI #ComputationalBiology

  17. If you are interested in how AI can support the development of scientific software, I invite you to attend my workshop at the 71st Annual Meeting of the Biophysical Society in Philadelphia.

    On February 23, 2027, at 7:30 PM, I will present “Developing Scientific Software with AI: Opportunities, Practices, and Pitfalls for Biophysicists.”

    I am grateful for the invitation and look forward to the discussion.

    See you at #BPS2027 #Biophysics #AI #ComputationalBiology

  18. Researchers have identified specific structural features in the spleen, visible on MRI scans, that are associated with an increased risk of coronary artery disease (CAD).
    #Genetics #ComputationalBiology #ArtificialIntelligence (Machine Learning) #Radiology #sflorg
    sflorg.com/2026/09/med09122601

  19. Researchers have identified specific structural features in the spleen, visible on MRI scans, that are associated with an increased risk of coronary artery disease (CAD).
    #Genetics #ComputationalBiology #ArtificialIntelligence (Machine Learning) #Radiology #sflorg
    sflorg.com/2026/09/med09122601

  20. Researchers have identified specific structural features in the spleen, visible on MRI scans, that are associated with an increased risk of coronary artery disease (CAD).
    #Genetics #ComputationalBiology #ArtificialIntelligence (Machine Learning) #Radiology #sflorg
    sflorg.com/2026/09/med09122601

  21. Researchers have identified specific structural features in the spleen, visible on MRI scans, that are associated with an increased risk of coronary artery disease (CAD).
    #Genetics #ComputationalBiology #ArtificialIntelligence (Machine Learning) #Radiology #sflorg
    sflorg.com/2026/09/med09122601

  22. Researchers have identified specific structural features in the spleen, visible on MRI scans, that are associated with an increased risk of coronary artery disease (CAD).
    #Genetics #ComputationalBiology #ArtificialIntelligence (Machine Learning) #Radiology #sflorg
    sflorg.com/2026/09/med09122601

  23. rarelens: building a rare-disease variant triage platform, and the four things I got wrong

    An end-to-end rare-disease variant triage platform: a Nextflow pipeline, three execution backends behind one API call, Terraform for two cloud tracks, and a phenotype-driven ranking measured against 10,178 published cases. Including the model metric that collapsed to exactly random once I removed the feature doing all the work.

    kemal.yaylali.uk/rarelens-tech

  24. rarelens: building a rare-disease variant triage platform, and the four things I got wrong

    An end-to-end rare-disease variant triage platform: a Nextflow pipeline, three execution backends behind one API call, Terraform for two cloud tracks, and a phenotype-driven ranking measured against 10,178 published cases. Including the model metric that collapsed to exactly random once I removed the feature doing all the work.

    kemal.yaylali.uk/rarelens-tech

  25. rarelens: building a rare-disease variant triage platform, and the four things I got wrong

    An end-to-end rare-disease variant triage platform: a Nextflow pipeline, three execution backends behind one API call, Terraform for two cloud tracks, and a phenotype-driven ranking measured against 10,178 published cases. Including the model metric that collapsed to exactly random once I removed the feature doing all the work.

    kemal.yaylali.uk/rarelens-tech

  26. rarelens: building a rare-disease variant triage platform, and the four things I got wrong

    An end-to-end rare-disease variant triage platform: a Nextflow pipeline, three execution backends behind one API call, Terraform for two cloud tracks, and a phenotype-driven ranking measured against 10,178 published cases. Including the model metric that collapsed to exactly random once I removed the feature doing all the work.

    kemal.yaylali.uk/rarelens-tech

  27. Computational Biologist - Fully Remote
    micro1

    Computational Biologists (MSc or PhD) needed for fully remote contract work (up to $120/hour!). Ideally looking for experience in medicinal chemistry

    See the full job description on jobRxiv: jobrxiv.org/job/micro1-27778-c

    ...
    jobrxiv.org/job/micro1-27778-c

  28. 🔬 What if a tumor sample could serve as its own reference?

    🔗 Reference-Free Microsatellite Instability Detection from Tumor Sequencing Using Intrasample Variability Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: doi.org/10.34133/csbj.0219

    📚 CSBJ - A Science Partner Journal: spj.science.org/journal/csbj

    #MicrosatelliteInstability #MSI #CancerGenomics #NextGenerationSequencing #ComputationalBiology #Genomics #PersonalizedMedicine #Oncology #Biomarkers #PrecisionMedicine

  29. 🔬 What if a tumor sample could serve as its own reference?

    🔗 Reference-Free Microsatellite Instability Detection from Tumor Sequencing Using Intrasample Variability Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: doi.org/10.34133/csbj.0219

    📚 CSBJ - A Science Partner Journal: spj.science.org/journal/csbj

    #MicrosatelliteInstability #MSI #CancerGenomics #NextGenerationSequencing #ComputationalBiology #Genomics #PersonalizedMedicine #Oncology #Biomarkers #PrecisionMedicine

  30. 🔬 What if a tumor sample could serve as its own reference?

    🔗 Reference-Free Microsatellite Instability Detection from Tumor Sequencing Using Intrasample Variability Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: doi.org/10.34133/csbj.0219

    📚 CSBJ - A Science Partner Journal: spj.science.org/journal/csbj

    #MicrosatelliteInstability #MSI #CancerGenomics #NextGenerationSequencing #ComputationalBiology #Genomics #PersonalizedMedicine #Oncology #Biomarkers #PrecisionMedicine

  31. 🔬 What if a tumor sample could serve as its own reference?

    🔗 Reference-Free Microsatellite Instability Detection from Tumor Sequencing Using Intrasample Variability Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: doi.org/10.34133/csbj.0219

    📚 CSBJ - A Science Partner Journal: spj.science.org/journal/csbj

    #MicrosatelliteInstability #MSI #CancerGenomics #NextGenerationSequencing #ComputationalBiology #Genomics #PersonalizedMedicine #Oncology #Biomarkers #PrecisionMedicine

  32. 🔬 What if a tumor sample could serve as its own reference?

    🔗 Reference-Free Microsatellite Instability Detection from Tumor Sequencing Using Intrasample Variability Modeling. Computational and Structural Biotechnology Journal (CSBJ). DOI: doi.org/10.34133/csbj.0219

    📚 CSBJ - A Science Partner Journal: spj.science.org/journal/csbj

    #MicrosatelliteInstability #MSI #CancerGenomics #NextGenerationSequencing #ComputationalBiology #Genomics #PersonalizedMedicine #Oncology #Biomarkers #PrecisionMedicine

  33. ⚛️ Would today’s antibiotics still work if bacterial biology were flipped at the molecular level?

    🔗 Molecular Dynamics Simulations Demonstrate Reduced Antibiotic Affinity to Mirror Bacterial Targets. Computational and Structural Biotechnology Journal (CSBJ). DOI: doi.org/10.34133/csbj.0198

    📚 CSBJ - A Science Partner Journal: spj.science.org/journal/csbj

    #MolecularDynamics #Antibiotics #Biosecurity #ComputationalBiology #SyntheticBiology #DrugDiscovery #AntimicrobialResearch #ComputationalChemistry

  34. ⚛️ Would today’s antibiotics still work if bacterial biology were flipped at the molecular level?

    🔗 Molecular Dynamics Simulations Demonstrate Reduced Antibiotic Affinity to Mirror Bacterial Targets. Computational and Structural Biotechnology Journal (CSBJ). DOI: doi.org/10.34133/csbj.0198

    📚 CSBJ - A Science Partner Journal: spj.science.org/journal/csbj

    #MolecularDynamics #Antibiotics #Biosecurity #ComputationalBiology #SyntheticBiology #DrugDiscovery #AntimicrobialResearch #ComputationalChemistry

  35. A mathematical modeling approach used to optimize the composition, diversity, and timing of bacteriophage cocktails for treating drug-resistant bacterial infections.
    #ComputationalBiology #MathematicalBiology #Microbiology #InfectiousDiseases #sflorg
    sflorg.com/2026/08/cobi0829260

  36. A mathematical modeling approach used to optimize the composition, diversity, and timing of bacteriophage cocktails for treating drug-resistant bacterial infections.
    #ComputationalBiology #MathematicalBiology #Microbiology #InfectiousDiseases #sflorg
    sflorg.com/2026/08/cobi0829260

  37. A mathematical modeling approach used to optimize the composition, diversity, and timing of bacteriophage cocktails for treating drug-resistant bacterial infections.
    #ComputationalBiology #MathematicalBiology #Microbiology #InfectiousDiseases #sflorg
    sflorg.com/2026/08/cobi0829260

  38. A mathematical modeling approach used to optimize the composition, diversity, and timing of bacteriophage cocktails for treating drug-resistant bacterial infections.
    #ComputationalBiology #MathematicalBiology #Microbiology #InfectiousDiseases #sflorg
    sflorg.com/2026/08/cobi0829260

  39. A mathematical modeling approach used to optimize the composition, diversity, and timing of bacteriophage cocktails for treating drug-resistant bacterial infections.
    #ComputationalBiology #MathematicalBiology #Microbiology #InfectiousDiseases #sflorg
    sflorg.com/2026/08/cobi0829260

  40. The nuclear pore complex (7R5J & 7R5K) – one of the largest molecular machines in biology.

    The nuclear pore complex is the gatekeeper of the cell nucleus – controlling everything that enters or leaves. We captured it in two states: open (dilated) and closed (constricted).

    961665 quantum records

    exxogen.hu/

    ​#StructuralBiology #Biophysics #Bioinformatics #Topology #InformationTheory #DNAFolding #ComputationalBiology #ComplexSystems #Genomics #OpenScience #EXXOGEN

  41. What if the biological sequence of these 3 billion base pairs is completely irrelevant... and the human genome was never written to be read, but folded? What if the information isn't carried by the linear code, but by the spatial geometry the molecule closes around itself, and we are merely trying to decipher a 3D shadow cast by a higher-dimensional structure?

    exxogen.hu/

    ​#Biophysics #Bioinformatics #InformationTheory #DNA #ComputationalBiology #ComplexSystems #Genomic #EXXOGEN

  42. What if the biological sequence of these 3 billion base pairs is completely irrelevant... and the human genome was never written to be read, but folded? What if the information isn't carried by the linear code, but by the spatial geometry the molecule closes around itself, and we are merely trying to decipher a 3D shadow cast by a higher-dimensional structure?

    exxogen.hu/

    ​#Biophysics #Bioinformatics #InformationTheory #DNA #ComputationalBiology #ComplexSystems #Genomic #EXXOGEN