#codon — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #codon, aggregated by home.social.
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`Through genome-wide CRISPR screening, we identified the RNA-binding protein DHX29 as a critical regulator of codon-dependent gene expression. Cryogenic electron microscopy and selective ribosome profiling demonstrated that DHX29 directly interacts with the A-site entrance of the translating 80S ribosome... These findings establish a mechanistic link between synonymous codon usage and the regulation of gene expression.`
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`Through genome-wide CRISPR screening, we identified the RNA-binding protein DHX29 as a critical regulator of codon-dependent gene expression. Cryogenic electron microscopy and selective ribosome profiling demonstrated that DHX29 directly interacts with the A-site entrance of the translating 80S ribosome... These findings establish a mechanistic link between synonymous codon usage and the regulation of gene expression.`
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`Through genome-wide CRISPR screening, we identified the RNA-binding protein DHX29 as a critical regulator of codon-dependent gene expression. Cryogenic electron microscopy and selective ribosome profiling demonstrated that DHX29 directly interacts with the A-site entrance of the translating 80S ribosome... These findings establish a mechanistic link between synonymous codon usage and the regulation of gene expression.`
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`Through genome-wide CRISPR screening, we identified the RNA-binding protein DHX29 as a critical regulator of codon-dependent gene expression. Cryogenic electron microscopy and selective ribosome profiling demonstrated that DHX29 directly interacts with the A-site entrance of the translating 80S ribosome... These findings establish a mechanistic link between synonymous codon usage and the regulation of gene expression.`
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`Through genome-wide CRISPR screening, we identified the RNA-binding protein DHX29 as a critical regulator of codon-dependent gene expression. Cryogenic electron microscopy and selective ribosome profiling demonstrated that DHX29 directly interacts with the A-site entrance of the translating 80S ribosome... These findings establish a mechanistic link between synonymous codon usage and the regulation of gene expression.`
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New tool!
https://keiran-rowell.github.io/assets/interactive/codon-rarity-viewer/
I vibe coded a web app version of my Rare Codon Table #python script🧬 🧮 maps rare codons onto a PDB structure.
I originally wrote a script to find protein codon rarity differences in mammalian -> bacterial expression projects.
🐍 Runs entirely locally via Pyodide — your data never leaves your browser (no server uploads)
Feedback warmly welcomed! Please let me know if there are any issues.
#bioinformatics #codon #structuralbiology #pyodide #WASM #proteins
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DATE: December 15, 2025 at 05:30PM
SOURCE: BioWorld MedTechDirect article link at end of text block below.
.@alltrna advances #tRNA-based strategy for stop #codon diseases
Here are any URLs found in the article text:
Articles can be found by scrolling down the page at https://www.bioworld.com/topics/85-bioworld-medtech .
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#Queuosine-#tRNA promotes sex-dependent learning and memory formation by maintaining #codon-biased translation elongation speed
Francesca Tuorto and coworkers
https://www.embopress.org/doi/full/10.15252/embj.2022112507
