#cleantheair — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #cleantheair, aggregated by home.social.
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Clean the air in your dorm room with a Corsi-Rosenthal Box DIY Air Purifier Kit. The kit is on sale now for $199.99! 🎉
We also have North Box Air Purifier Kits, which are quieter and smaller, for sale. 💨
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Macitentan - an approved dual endothelin receptor antagonist used for pulmonary hypertension. In hamsters it reduced iron accumulation, cellular senescence, and bone loss. Two windows were tested -acute (days 1-3) and delayed (16-30).
The human piece. Plasma ET-1 in 4 vs 4 people, ex vivo lung, 1 sample vs 1 cartilage, 3 controls vs 5 post-COVID, cross-sectional, pre-pandemic controls. The authors - the cohort is powered only to detect very large effects and call the finding exploratory. Causality and chronicity aren't established.The damaged growth plate is a finding in juvenile animals, so relevant to children, whose growth plates are still open. The adult human finding sits elsewhere - articular and subchondral. Bone after COVID in a child and in an adult aren't the same thing.
The authors themselves add a recommendation here. Given the growth plate's role in longitudinal bone growth, and a growing but still scattered set of clinical reports of children with bone loss, knee bone erosion, or joint pain after COVID, they call for monitoring bone age and growth velocity in children after infection - noting these complications may be underrecognized. @szupraha @ZdravkoOnline @adamvojtech86
Ni at al., #CovidIsNotOver #MASK4YOURLIFE #CleanTheAir
Lung epithelial endothelin-1 drives iron dysregulation and skeletal injury after SARS-CoV-2 infection
https://www.cell.com/cell-reports/fulltext/S2211-1247(26)00919-8
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The worst air quality in the world? Chilliwack and Sunshine Valley AQI > 300, Hozomeen AQI reaching 3000. [1]
For scale, 3000 ug/m3 is hundreds of times the recommended limit:
The EPA is setting the level of the primary (health-based) annual PM2.5 standard at 9.0 micrograms per cubic meter (μg/ m3) [2]
Awful, terrible, no-good air.
Wear a mask! Run air purifiers! Trust your nose if you smell smoke, and your eyes when you see haze!
[1] https://map.purpleair.com/air-quality-standards-us-epa-aqi?opt=%2F1%2Flp%2Fa10%2Fp604800%2FcC0#8.79/49.0254/-121.2742/-55.2/59
[2] https://www.epa.gov/system/files/documents/2024-02/pm-naaqs-air-quality-index-fact-sheet.pdf -
The study identified a dysregulated immune environment in Long COVID tissue in which the two branches of the immune system that normally work together – the innate and the adaptive immune systems – showed strikingly different responses.
Innate immune cells showed continued inflammatory and viral-sensing activity, while the adaptive pathways needed to recognize & eliminate infected cells including antigen presentation, phagocytosis, and cytotoxic immune function were downregulated. The human gastrointestinal tract must allow contact with foreign materials (i.e., food) without triggering immune activation, and the SARS-CoV-2 virus may have immune evasion tactics to take advantage of this environment.
The study’s tissue biopsy results are evidence that SARS-CoV-2 exploits, or is inadvertently protected by, the gastrointestinal tract’s uniquely tolerogenic immune environment that restrains adaptive immune activation (such as antibodies or T cells), while viral reservoirs continued driving innate immune activation (i.e., inflammation).
“These findings suggest that Long COVID may involve a tissue immune environment that continues to sense persistent viral activity while failing to effectively clear virus-containing cells,” said Amy Proal, PhD, President and Research Director of PolyBio Research Foundation. 14/
“The fact that these inflammation-driving reservoirs may be extremely low-abundance & unevenly distributed across tissues also underscores why persistent virus can be so difficult to detect.”
Strikingly, abnormalities were far more apparent in tissue than blood.
Researchers identified 240 significantly altered genes in colorectal tissue but only three in matched peripheral blood immune cells, suggesting that important Long COVID biology may be compartmentalized within tissues and poorly reflected in conventional blood measurements.
The findings provide a rationale for treatment strategies that target both persistent viral reservoirs and the tissue immune dysfunction that may allow them to remain.#CovidIsNotOver #mask4yourlife #cleantheair
https://www.biorxiv.org/content/10.64898/2026.08.07.743616v1 -
Breaking: New Study Reveals Substantial Tissue-Level Immune Dysfunction Near Persistent Viral Reservoirs in Long COVID
PolyBio-funded UCSF research finds persistent SARS-CoV-2 RNA alongside an altered gut immune response that may impair viral clearance
Viral RNA was identified within the intestinal epithelium & also deeper tissue compartments. Because intestinal epithelial cells normally turn over within days, the presence of viral RNA in these cells months to years after initial infection is suggestive of ongoing viral activity or re-seeding of the tissue.
Importantly, the researchers caution that the study likely underestimates the prevalence of SARS-CoV-2 persistence. Persistent viral RNA is present at extremely low abundance relative to human RNA, making it technically difficult to detect.
Moreover, the endoscopic biopsy samples collected by the research team contain only a minute fraction of the ~25-30 foot (7-9 meter) long gastrointestinal tract.
Viral reservoirs could therefore be focal, intermittent or concentrated in nearby or distant anatomical locations that were not sampled, meaning a negative colorectal biopsy does not rule out persistence elsewhere.#CovidIsNotOver #mask4yourlife #cleantheair
https://www.biorxiv.org/content/10.64898/2026.08.07.743616v1 -
RE: https://jawns.club/@skyfaller/115917363561048559
I have made zero progress in building a PAPR stroller because I'm stuck at the "acquire a PAPR" step.
Does anyone have advice for specific PAPR models to buy, and/or where to buy them? They seem to run either very expensive or suspiciously cheap, and I have no idea what is trustworthy.
#PAPR #CleanTheAir #CovidIsNotOver #COVIDisAirborne #AirFiltration #smoke
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Advocacy opportunity 📣 BC's Finance committee is now accepting written feedback on what to include in BC's 2027 budget. This is a critical chance to tell policy-makers to support clean air, Long COVID care, testing, wastewater monitoring and more.
Learn how to submit your written feedback at https://donoharmbc.ca/bc-government-2027-budget.../ - and find some sample answers you can use to make it easier! In past years, budget feedback has resulted in some notable successes - including a 2024 commitment of over $3 billion in continued pandemic funding.
This year's feedback deadline is 2 pm (Pacific Time) on Friday, June 19. Note that if you're already scheduled to present directly to the finance committee, you do *not* need to do a written submission as well.
#BCBudget #BCBudget2027 #BCHealthcare #CleanTheAir #CleanAirEverywhere #LongCovid #NovavaxNow #N95sSaveLives #CovidIsNotOver
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Hantavirus outbreak should reset WHO’s default approach to airborne risk
https://www.bmj.com/content/393/bmj.s919
> Hantavirus is a pathogen with documented person-to-person transmission and high case fatality. Therefore, the starting point should not be to downplay the risk of airborne transmission until it is definitively proven.
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@DenisCOVIDinfoguy I see it in every hospital in Victoria, BC & yet majority of staff aren't masked. I'm one of very few people in health care services, who have to see clients in all 3 of the hospitals here, who never stopped masking up. Cleaner air systems haven't been installed to increase public health safety in hospitals either. Our health care system will collapse - physically & financially - if provincial & federal governments keep ignoring covid & the many dire, costly, medical consequences it brings.
#BCpoli #CDNpoli #medical #Healthcare #FailureToProtect #HealthCareCrisis #Covid #MasksSaveLives #CovidSafety #AirborneInfections #CleanTheAir #PreventativeHealth #WearAMask
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Advocacy opportunity 📣 The Metro Vancouver region has a survey seeking input on their 2027 Budget and Five-Year Financial Plan.
Metro Vancouver deals with things like wastewater, air quality, regional planning, providing below-market rental housing and more. (Note that they don’t just serve Vancouver - they serve many municipalities, which are listed in the survey.)
Take the survey until March 27, and be sure to let them know that you care about:
- wastewater testing / monitoring for communicable diseases
- air quality improvements, including indoor air quality and aligning building codes with up-to-date air quality standards like ASHRAE 241!Take the survey: https://engage.zencity.io/metrovancouver/en/engagements/f9f277fa-e5da-4654-8df3-faa38cc4d4bf
Learn more about the budget process: https://metrovancouver.org/about-us/budgets-and-financial-plans
#CleanTheAir #CleanIndoorAir #WastewaterMonitoring #CovidIsNotOver #MetroVancouver
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I'm still trying to wrap my head around the concept of an airborne-transmission-informed #publichealth body, let alone one that knows how to communicate...?!? 🏆🏆🏆
𝘿𝙪𝙧𝙝𝙖𝙢 𝘾𝙤𝙪𝙣𝙩𝙮 𝘿𝙚𝙥𝙖𝙧𝙩𝙢𝙚𝙣𝙩 𝙤𝙛 𝙋𝙪𝙗𝙡𝙞𝙘 𝙃𝙚𝙖𝙡𝙩𝙝, 𝘷𝘪𝘢 𝘉𝘭𝘶𝘦𝘚𝘬𝘺 (@𝘥𝘶𝘳𝘩𝘢𝘮𝘩𝘦𝘢𝘭𝘵𝘩𝘯𝘤.𝘣𝘴𝘬𝘺.𝘴𝘰𝘤𝘪𝘢𝘭):
"An airborne virus is a virus that can infect other people through unseen particles in the air, sometimes for hours after the sick person has left the area! Masks and clean, ventilated air can reduce the risk of getting sick from airborne viruses or infecting others."
https://www.youtube.com/shorts/4zO-zE_ZUwQ
#CovidIsAirborne #airbornetransmission #CleanAir #CleanTheAir #CovidIsNotOver
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@Sidherian
Looks like the link for the NSW Parliament inquiry into indoor air quality got truncated; it's https://www.parliament.nsw.gov.au/committees/inquiries/Pages/inquiry-details.aspx?pk=3152 -
#C0VIDisnotover #maskforyourlife #cleantheair
As some might know I’m in regular contact with NSW politician to whom I send COVID related papers & articles.
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Start the new year with cleaner air. 💨 Pick up a DIY Corsi-Rosenthal Kit and build your own Corsi-Rosenthal Box. The kit is on sale for only $199.99! 🎉 But don’t wait because the sale ends today. ⏰