home.social

#chloride — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #chloride, aggregated by home.social.

  1. "The #structure reveals rGAT1 in a cytosol-facing #conformation, with a linear density in the primary binding site that accommodates a molecule of #GABA, a displaced ion density proximal to Na site 1 and a bound #chloride ion. A unique insertion in TM10 aids the formation of a compact, closed #extracellular gate. Besides yielding mechanistic insights into #ion and substrate recognition, our study will enable the #rational #design of specific #antiepileptics."

    nature.com/articles/s41594-023