#chd8 — Public Fediverse posts

Chromatin remodeling tied to altered splicing in autism model

https://www.spectrumnews.org/news/chromatin-remodeling-tied-to-altered-splicing-in-autism-model/

#bioinformatics #geneexpression #valproicacid #epigenetics #sequencing #chromatin #synapses #autism #News #CHD8

CHD8 mutation in 33 mouse strains yields range of traits

https://www.spectrumnews.org/news/chd8-mutation-in-33-mouse-strains-yields-range-of-traits/

#macrocephaly #mousemodels #anxiety #autism #News #CHD8

Flexible genomic architecture undergoes major redesigns during cerebellum development

https://www.spectrumnews.org/news/flexible-genomic-architecture-undergoes-major-redesigns-during-cerebellum-development/

#cerebellum #chromatin #autism #News #CHD8

Community Newsletter: Autism gene lists, genetic diversity in mouse models, an autism biomarker

https://www.spectrumnews.org/news/community-newsletter-autism-gene-lists-genetic-diversity-in-mouse-models-an-autism-biomarker/

#faceprocessing #mousemodels #biomarkers #community #autism #News #CHD8 #EEG

‘Double duty’ autism-linked genes upend conventional characterizations

https://www.spectrumnews.org/news/double-duty-autism-linked-genes-upend-conventional-characterizations/

#chromatin #organoids #synapses #autism #cortex #News #CHD8

Heart anomalies abound in mouse models of autism

https://www.spectrumnews.org/news/heart-anomalies-abound-in-mouse-models-of-autism/

#fragileXsyndrome #mousemodels #16p11.2 #autism #SHANK3 #News #CHD8 #FMR1

Organoids show how mutations in top autism gene may lead to brain overgrowth in people

https://www.spectrumnews.org/news/organoids-show-how-mutations-in-top-autism-gene-may-lead-to-brain-overgrowth-in-people/

#endophenotype #macrocephaly #organoids #autism #News #CHD8

Three autism-linked genes converge on tweaks to cells’ timing

https://www.spectrumnews.org/news/three-autism-linked-genes-converge-on-tweaks-to-cells-timing/

#signalingimbalance #macrocephaly #chromatin #organoids #autism #News #CHD8 #GABA

Fish, frogs, flies and other fauna in scientific firsts

https://www.spectrumnews.org/features/fish-frogs-flies-and-other-fauna-in-scientific-firsts/

#neurotransmitters #fragileXsyndrome #Drosophila #C.elegans #zebrafish #Features #language #16p11.2 #CNTNAP2 #autism #SHANK3 #sleep #CHD8 #FMR1 #gut

Disruptions to brain’s ‘thermostat’ may underpin autism traits

https://www.spectrumnews.org/news/disruptions-to-brains-thermostat-may-underpin-autism-traits/

#signalingimbalance #synapticplasticity #neuralcircuits #spokenversion #mousemodels #chromatin #epilepsy #autism #genes #News #CHD8

Sleep problems in autism may stem from leaky brain barrier

https://www.spectrumnews.org/news/sleep-problems-in-autism-may-stem-from-leaky-brain-barrier/

#autism #sleep #News #CHD8

Mapping the futures of autistic children

https://www.spectrumnews.org/features/deep-dive/mapping-the-futures-of-autistic-children/

#behavioralinterventions #intellectualdisability #repetitivebehavior #spokenversion #severeautism #motorskills #depression #treatments #education #DeepDive #language #anxiety #autism #DYRK1A #GRIN2B #SCN2A #ADNP #CHD8 #IQ