#channelrhodopsin — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #channelrhodopsin, aggregated by home.social.
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Adam Claridge-Chang and Shiqiang Gao analyse K+ channelrhodopsins:
"both the absolute K+ to Na+ permeability ratio and its stability over time determine the inhibition to activation transition, which limits their utility for silencing neural circuits."
And they found that a single aminoacid mutant, KCR1-C29D, "shows a relatively high and the most stable K+ to Na+ permeability ratio during illumination", better than heavily protein engineered versions.
"Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins", Duan et al. 2025
https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202509180 -
“To expand the repertoire of endogenous cellular communication, we developed a synthetic, photon-assisted synaptic transmission (PhAST) system. PhAST is based on luciferases and channelrhodopsins that enable the transmission of a neuronal state across space, using photons as neurotransmitters.”
Porta-de-la-Riva et al. 2023 https://www.nature.com/articles/s41592-023-01836-9
What a fun project and cool finding, and made in #Catalunya to top it off at the Photonic Science Institute.
Combine that with #photopharmacology and neural circuits may be able to dose themselves according to activity patterns.
#neuroscience #PhAST #Luciferase #ChannelRhodopsin #biophotonics #optogenetics
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“To expand the repertoire of endogenous cellular communication, we developed a synthetic, photon-assisted synaptic transmission (PhAST) system. PhAST is based on luciferases and channelrhodopsins that enable the transmission of a neuronal state across space, using photons as neurotransmitters.”
Porta-de-la-Riva et al. 2023 https://www.nature.com/articles/s41592-023-01836-9
What a fun project and cool finding, and made in #Catalunya to top it off at the Photonic Science Institute.
Combine that with #photopharmacology and neural circuits may be able to dose themselves according to activity patterns.
#neuroscience #PhAST #Luciferase #ChannelRhodopsin #biophotonics #optogenetics
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“To expand the repertoire of endogenous cellular communication, we developed a synthetic, photon-assisted synaptic transmission (PhAST) system. PhAST is based on luciferases and channelrhodopsins that enable the transmission of a neuronal state across space, using photons as neurotransmitters.”
Porta-de-la-Riva et al. 2023 https://www.nature.com/articles/s41592-023-01836-9
What a fun project and cool finding, and made in #Catalunya to top it off at the Photonic Science Institute.
Combine that with #photopharmacology and neural circuits may be able to dose themselves according to activity patterns.
#neuroscience #PhAST #Luciferase #ChannelRhodopsin #biophotonics #optogenetics
-
“To expand the repertoire of endogenous cellular communication, we developed a synthetic, photon-assisted synaptic transmission (PhAST) system. PhAST is based on luciferases and channelrhodopsins that enable the transmission of a neuronal state across space, using photons as neurotransmitters.”
Porta-de-la-Riva et al. 2023 https://www.nature.com/articles/s41592-023-01836-9
What a fun project and cool finding, and made in #Catalunya to top it off at the Photonic Science Institute.
Combine that with #photopharmacology and neural circuits may be able to dose themselves according to activity patterns.
#neuroscience #PhAST #Luciferase #ChannelRhodopsin #biophotonics #optogenetics
-
“To expand the repertoire of endogenous cellular communication, we developed a synthetic, photon-assisted synaptic transmission (PhAST) system. PhAST is based on luciferases and channelrhodopsins that enable the transmission of a neuronal state across space, using photons as neurotransmitters.”
Porta-de-la-Riva et al. 2023 https://www.nature.com/articles/s41592-023-01836-9
What a fun project and cool finding, and made in #Catalunya to top it off at the Photonic Science Institute.
Combine that with #photopharmacology and neural circuits may be able to dose themselves according to activity patterns.
#neuroscience #PhAST #Luciferase #ChannelRhodopsin #biophotonics #optogenetics
