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#cellsignaling — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #cellsignaling, aggregated by home.social.

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  1. 💊 Can understanding receptor bias help us design safer, more selective GPCR drugs?

    🔗 Biased activation of the vasopressin V2 receptor probed by molecular dynamics simulations, NMR and pharmacological studies. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.csbj.2024.10

    📚 CSBJ: csbj.org/

    #GPCR #StructuralBiology #MolecularDynamics #NMR #Pharmacology #ProteinStructure #DrugDiscovery #ComputationalBiology #CellSignaling

  2. 📣📣📣 Latest news from the NephroLab Cologne – more specifically, from our 🦛 Hippo- Team:
    Our snRNA-Seq study on YAP and TAZ in kidney podocytes is now online open access in JASN! 🥳 🎉 🐙
    Huge thanks to everyone on the team and the incredibly thorough reviewers at JASN!

    Link: journals.lww.com/jasn/abstract

    #HippoSignaling #YAP #TAZ #Kidney #Kidneydisease #Science #snRNASeq #cellsignaling #FSGS #podocyte #Nephrology #Niere #Nephrolab #Nephrologie

    @ukkoeln @UniKoeln @CECAD

  3. A developer of treatments for Alzheimer's disease that seeks to improve the condition of the brain's support cells is raising £48 million ($US 61 million) in its first venture round.

    sciencebusiness.technewslit.co

    #News #Press #Science #Business #Biotechnology #Neuroscience #AlzheimersDisease #Dementia #Astrocytes #Neurodegenerative #CellSignaling #Licensing #Finance #VentureCapital

  4. The dose & duration of type I #interferon exposure is interpreted by a signaling module with a stimulus-contingent positive feedback loop. A secondary potentiated phase of ISGF3 activates pro-inflammatory gene expression ➡️ embopress.org/doi/full/10.1525 #cellsignaling #SystemsBiology
    from Alex Hoffmann, UCLA

  5. A new proteomic workflow establishing interdependencies between protein #phosphorylation & complex formation is applied to the signal integrator & Hippo pathway effector YAP1 ➡️ bit.ly/3mJ4W0t
    Matthias Gstaiger @eth_en
    #proteomics #interactome #ProteinProteinInteractions #CellSignaling

  6. Modeling & experimental analyses of a Golgi-localized GTPase circuitry that allows cancer cells to achieve self-sufficiency in growth factor signaling ➡️ bit.ly/41DK7Dj
    P Rangamani & P Ghosh, UCSD
    #Gproteins #CellSignaling #EGFR #SystemsBiology