#cd8 — Public Fediverse posts

Identification of HLA-A33-restricted #CD8+ T cell epitopes from avian #influenza #H5N1, https://etidiohnew.blogspot.com/2026/06/identification-of-hla-a33-restricted.html

Protesters gathered peacefully on the I25 overpass near #Dacono & #Frederick to draw attention to the inhumane #ICEBlackSite #ICEHoldArea in the area.
Thank you to #ColoradoBridgeTrolls & #50501 for organizing. #CD8 #CO8 #WeldCounty #ICEOutforGood

#Cancer immunotherapy is a type of cancer treatment that harnesses the #immune system to fight cancer cells. The treatment involves #CD8⁺ T cells, also known as killer T cells, which play a crucial role in attacking #tumors
#Immunology #Oncology #Metabolomics #sflorg
https://www.sflorg.com/2026/01/imgy01212601.html

Perforin is the substance T and NK cells use to drill into an infected cell and kill it. Selin and Gill’s studies suggest that ME/CFS and long-COVID patients’ T cells produce almost no perforin

https://www.healthrising.org/wp-content/uploads/2025/05/Perforin_Selin_Webinar_25.gif

[alt text: graphs of perforin in two classes of cell. The healthy controls are tall grey bars, compared to 1/10 to 1/3 as tall bars for Long COVID and ME/CFS groups.]

they also found

a huge increase in a distinct type of T-cell called double-positive T-cell (CD4+ CD8+) in people with ME/CFS and/or long COVID. Instead of being differentiated into the two usual major T-cell subsets CD4 (helper/regulatory) and CD8 (killer) T-cells, these hybrid T-cells look like both CD4 and CD8 T-cells at the same time.

Selin found that these cells increased 8-9 fold in ME/CFS and long-COVID patients.

which compensates in part for the lower perforin, but also led to

a “highly dysregulated” cytotoxic T-cell immune response [...] That suggested that the immune system was kind of flailing around, trying to come up with an answer.

from https://www.healthrising.org/blog/2025/05/15/t-cell-exhaustion-chronic-fatigue-long-covid/

#COVID #COVID19 #MECFS #LongCOVID #CovidIsNotOver #TCells #NKCells #CD8 #CD4

A genetically engineered therapeutic #lectin inhibits #human #influenza A virus #infection and sustains robust virus-specific #CD8 T cell expansion, https://etidiohnew.blogspot.com/2025/05/a-genetically-engineered-therapeutic.html

Role of #antiviral #CD8+ T cell #immunity to #SARS-CoV-2 #infection and #vaccination, https://etidiohnew.blogspot.com/2025/03/role-of-antiviral-cd8-t-cell-immunity.html

Year of Fantasy RPGS: Cd8 The Return of the Fearless Five!
I am still having fun with Jason Vey's Cd8 Fantasy Roleplaying game. I thought I would give it a spin with some more characters. Getting a feeling of what the various power level benchmarks are and so on. So I thought, let's bring back the Fearless Five and give them a go at it!
#ttrpg #classic #cd8
https://theotherside.timsbrannan.com/2025/02/year-of-fantasy-rpgs-cd8-return-of.html

Revealing novel #CD8+ T-cell #epitopes from the #H5N1 avian #influenza virus in HBW/B1 haplotype #ducks, https://etidiohnew.blogspot.com/2024/12/revealing-novel-cd8-t-cell-epitopes.html

#CD8+ T #cell epitope conservation in emerging #H5N1 viruses suggests global protection

Source: Clinical and Translational Immunology, AbstractObjectivesThe recent H5N1 avian influenza outbreak in the USA has sparked fresh fears of avian viruses causing the next pandemic. To date, the H5N1 (clade 2.3.4.4b) outbreak in cattle has spread across several states in the USA, with several humans infected following exposure to cows. This H5N1 clade is also reportedly…

https://etidioh.wordpress.com/2024/11/25/cd8-t-cell-epitope-conservation-in-emerging-h5n1-viruses-suggests-global-protection/

🔁#Colorado #CD8 #Election2024 -Nov-5

BATTLEGROUND RACE:
Help Re-Elect YADIRA CARAVEO #CO08

✅Donate: https://secure.actblue.com/donate/dw_co08
✅Volunteer: https://www.mobilize.us/democratsworkforamerica/?org_ids=33696

#HarrisWalz2024 #KeepItBlue #WinBlue
#COpol #COpolitics #COleg #CO #MST
#Democrats #Education #Economy #Water #PublicLands #Healthcare
#DemsWork4USA #SheSePuede

🔁#Colorado #CD8 #Election2024 -Nov-5

BATTLEGROUND RACE:
Help Re-Elect YADIRA CARAVEO #CO08

✅Donate: https://secure.actblue.com/donate/dw_co08
✅Volunteer: https://www.mobilize.us/democratsworkforamerica/?org_ids=33696

#HarrisWalz2024 #KeepItBlue #WinBlue
#COpol #COpolitics #COleg #CO #MST
#Democrats #Education #Economy #Water #PublicLands #Healthcare
#DemsWork4USA #Vota

🔁#Colorado #CD8 #Election2024 -Nov-5

BATTLEGROUND RACE:
Help Re-Elect YADIRA CARAVEO #CO08

✅Donate: https://secure.actblue.com/donate/dw_co08
✅Volunteer: https://www.mobilize.us/democratsworkforamerica/?org_ids=33696

#HarrisWalz2024 #KeepItBlue #WinBlue
#COpol #COpolitics #COleg #CO #MST
#Democrats #Education #Economy #Water #PublicLands #Healthcare
#DemsWork4USA #Vota

The #frequency & #function of #nucleoprotein-specific #CD8+ T cells are critical for heterosubtypic #immunity against #influenza virus infection, J Virol.: https://journals.asm.org/doi/abs/10.1128/jvi.00711-24?af=R

We demonstrate that both CTL frequency & function are crucial for providing heterosubtypic immunity to influenza by utilizing an Ad-viral vector expressing a CD8 epitope only to rule out the role of antibodies, single-cell RNA-seq analysis, as well as adoptive transfer experiments.

Bystander activated #CD8 #Tcells mediate #neuropathology during #viral infection via antigen-independent #cytotoxicity

https://www.nature.com/articles/s41467-023-44667-0

#openaccess

https://www.nature.com/articles/s41467-023-44667-0.pdf

Single #cell spatial #analysis reveals #inflammatory foci of immature #neutrophil and #CD8 T cells in #COVID19 #lungs https://www.nature.com/articles/s41467-023-42421-0

#Antiviral effect of #SARS-CoV-2 N-specific #CD8 T cells induced in #lungs by engineered extracellular vesicles https://www.nature.com/articles/s41541-023-00686-y

Antitumor T-cell function requires #CPEB4-mediated adaptation to chronic #endoplasmic #reticulum stress

Raúl Méndez and colleagues at IRB Barcelona show that RNA-binding protein CPEB4 mediates transient unfolded protein response #UPR for stress adaptation in #CD8 #Tcells

https://www.embopress.org/doi/10.15252/embj.2022111494