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#cd47 — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #cd47, aggregated by home.social.

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  1. The News Lens @[email protected] ·
    AI時代新藥設計：漢康生技如何用「蛋白質工程」，賭一個45億美元授權？
    林昆輝（Quinn Lin） 2026-07-12 07:58:00 CST
    漢康的CD47新藥HCB101，運用AI輔助蛋白質工程，突破前代藥物安全性與療效的兩難，能高選擇性攻擊腫瘤而不傷紅血球，目標在完成概念驗證後進行國際授權。
    https://www.thenewslens.com/article/269119
    #蛋白質工程 #免疫系統 #AI輔助蛋白質工程 #腫瘤細胞 #FDA #巨噬細胞 #商業 #漢康 #免疫腫瘤 #HCB101 #AI #CD47 #國際授權
    #蛋白質工程 #免疫系統 #ai輔助蛋白質工程 #腫瘤細胞 #fda #巨噬細胞
  2. Thiago Carvalho @[email protected] ·

    Magrolimab is an anti-CD47

    'Gilead Sciences, Inc. today announced it has discontinued the Phase 3 ENHANCE-3 study of magrolimab in AML and that the (FDA) placed all magrolimab studies in myelodysplastic syndromes and AML, including related expanded access programs, on full clinical hold'
    #Leukemia #ClinicalTrial #CD47 #Hematology

    gilead.com/news-and-press/comp

    #leukemia #clinicaltrial #cd47 #hematology
  3. Arjan Boltjes @[email protected] ·

    " Instead, #Hepatoblastoma #tumors contain a large suppressive #myeloid compartment which poses opportunities for targeting. Specifically, therapeutic antibodies
    targeting the #tumor antigen #GPC3 to induce ADCP by #macrophages, in combination with myeloid
    #ImmuneCheckpointBlockade (#CD47/SIRPa, or VISTA) could be a feasible strategy to explore in future studies"

    Krijgsman et al. from Vercoulen lab in the #UMCUtrecht, on #bioRXiv:
    biorxiv.org/content/10.1101/20

    #scRNAseq #spatial #CyTOF #immunology

    #tumor #hepatoblastoma #tumors #myeloid #gpc3 #macrophages