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#cas9 — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #cas9, aggregated by home.social.

  1. bsky.app/profile/turkubioscien Turku Bioscience Genome Editing Core is organizing a workshop on generating knock-out and knock-in modification using CRISPR/Cas9 technology with in vitro ribonucleoprotein complex delivery.

    Read more & apply here: bioscience.fi/events/crispr-wo

    #geneediting #crispr #cas9 #utu #yliopisto

  2. bsky.app/profile/turkubioscien Turku Bioscience Genome Editing Core is organizing a workshop on generating knock-out and knock-in modification using CRISPR/Cas9 technology with in vitro ribonucleoprotein complex delivery.

    Read more & apply here: bioscience.fi/events/crispr-wo

    #geneediting #crispr #cas9 #utu #yliopisto

  3. bsky.app/profile/turkubioscien Turku Bioscience Genome Editing Core is organizing a workshop on generating knock-out and knock-in modification using CRISPR/Cas9 technology with in vitro ribonucleoprotein complex delivery.

    Read more & apply here: bioscience.fi/events/crispr-wo

    #geneediting #crispr #cas9 #utu #yliopisto

  4. Turku Bioscience Genome Editing Core is organizing a workshop on generating knock-out and knock-in modification using CRISPR/Cas9 technology with in vitro ribonucleoprotein complex delivery.

    Read more & apply here: bioscience.fi/events/crispr-wo

    #geneediting #crispr #cas9 bsky.app/profile/turkubioscien #utu #yliopisto

  5. 🧬 CRISPR technology is transforming genetics 🔬, enabling precise gene editing for research, diagnostics, and future therapeutic innovations 🚀.

    #CRISPR #GeneEditing #Biotechnology #MolecularBiology #Cas9 #Genomics #LifeScienceStudents #ResearchInnovation #BiotechTrends #BioResire

  6. 🧬 CRISPR technology is transforming genetics 🔬, enabling precise gene editing for research, diagnostics, and future therapeutic innovations 🚀.

    #CRISPR #GeneEditing #Biotechnology #MolecularBiology #Cas9 #Genomics #LifeScienceStudents #ResearchInnovation #BiotechTrends #BioResire

  7. Кроим ДНК на Python — CRISPR gRNA finder, Часть II: Скоринг, off-target и реальный ген

    В первой части мы написали базовый поиск gRNA с фильтрацией по GC-составу. Работает, но тупо: все кандидаты в диапазоне 40-60% считаются равнозначными. В реальности это не так. Сегодня добавим систему скоринга — будем ранжировать gRNA по качеству, учитывая позицию нуклеотидов и особенности U6-промотора. Потом подключим NCBI BLAST, чтобы проверять кандидатов на off-target: не порежет ли Cas9 что-нибудь лишнее в геноме. Тестировать будем на гене CCR5 — том самом, который отредактировал китайский учёный Хэ Цзянькуй в скандальном эксперименте 2018 года.

    habr.com/ru/articles/982876/

    #днк #cas9 #crispr #генетика #генная_инженерия #биоинформатика #биоинженерия #анализ_днк

  8. Кроим ДНК на Python: CRISPR gRNA finder, Часть I: Введение и базовый поиск

    Несколько лет назад я наткнулся на статью про CRISPR‑Cas9 и домашние биолаборатории — люди буквально у себя дома экспериментировали с редактированием генов. Я бэкенд‑разработчик, биологию последний раз открывал в школе, но желание разобраться никуда не делось. В этой статье разберёмся, как работает CRISPR на минимальном уровне, и напишем CLI‑утилиту на Python для поиска потенциальных guide RNA — «наводчиков» для молекулярных ножниц Cas9.

    habr.com/ru/articles/982664/

    #биоинформатика #биоинженерия #cas9 #crispr #днк #анализ_днк #чайникчайнику

  9. On this day in 2005: CRISPR noted to provide immunity and degrade DNA as means to prevent infection #CRISPR #Cas9 #ThisDayInBiotech

  10. On this day in 2005: CRISPR noted to provide immunity and degrade DNA as means to prevent infection #CRISPR #Cas9 #ThisDayInBiotech

  11. Researchers at the Broad Institute of MIT and Harvard and Cyrus Biotechnology have now #engineered two #CRISPR nucleases, #Cas9 and #Cas12, to mask them from the #immune system.
    #Biotechnology #Biomedical #sflorg
    sflorg.com/2025/01/biot0109250

  12. Researchers at the Broad Institute of MIT and Harvard and Cyrus Biotechnology have now #engineered two #CRISPR nucleases, #Cas9 and #Cas12, to mask them from the #immune system.
    #Biotechnology #Biomedical #sflorg
    sflorg.com/2025/01/biot0109250

  13. Bevor ich für @sciencenotes zu Grüner Gentechnik recherchiert habe, hatte ich keine Meinung zu dem Thema. Dann habe ich viele Studien gelesen. Und nun frage ich mich, wovor so viele Menschen Angst haben. Einen Überblick gibt's im #faq.

    #GeneEditing #Cas9 #CRISPR

    sciencenotes.de/faq-was-kann-g

  14. Bevor ich für @sciencenotes zu Grüner Gentechnik recherchiert habe, hatte ich keine Meinung zu dem Thema. Dann habe ich viele Studien gelesen. Und nun frage ich mich, wovor so viele Menschen Angst haben. Einen Überblick gibt's im #faq.

    #GeneEditing #Cas9 #CRISPR

    sciencenotes.de/faq-was-kann-g

  15. On this day in 2005: CRISPR noted to provide immunity and degrade DNA as means to prevent infection #CRISPR #Cas9 #ThisDayInBiotech

  16. On this day in 2005: CRISPR noted to provide immunity and degrade DNA as means to prevent infection #CRISPR #Cas9 #ThisDayInBiotech

  17. après l'achat de toutes les maisons d'édition de France au bénéfice d'une famille de miliardaires, le mégaéditeur acquert aussi le labo du MIT qui fait de l'édition génétique.

    #brokenNews #nouvellesPétées #CRISPR #CAS9

  18. Looking to perform genome-wide screens in bacteria? 🦠 Look no further than base editors—with a few tweaks #HIRI’s Beisel lab introduced to enhance the number of targetable sites. #baseediting #CRISPR #Cas9
    doi.org/10.1093/nar/gkae174

  19. Looking to perform genome-wide screens in bacteria? 🦠 Look no further than base editors—with a few tweaks #HIRI’s Beisel lab introduced to enhance the number of targetable sites. #baseediting #CRISPR #Cas9
    doi.org/10.1093/nar/gkae174

  20. Neue biotechnologische Methoden erlauben punktgenaue Eingriffe in das Erbgut – wie gut lassen sich Veränderungen nachweisen?

    Der aktuelle Wissensstand im #BfR2GO: bfr.bund.de/epaper/bfr2go_02_2

    #CRISPR #cas9 #GenomeEditing

  21. Neue biotechnologische Methoden erlauben punktgenaue Eingriffe in das Erbgut – wie gut lassen sich Veränderungen nachweisen?

    Der aktuelle Wissensstand im #BfR2GO: bfr.bund.de/epaper/bfr2go_02_2

    #CRISPR #cas9 #GenomeEditing

  22. #Bacteriophages encode anti-CRISPR proteins that inactivate bacterial #CRISPR-Cas systems, allowing successful invasion, replication & integration. This study shows that #antiCRISPR protein AcrIIA1 induces degradation of #Cas9 in human cells #PLOSBiology plos.io/3uUGAos

  23. #Bacteriophages encode anti-CRISPR proteins that inactivate bacterial #CRISPR-Cas systems, allowing successful invasion, replication & integration. This study shows that #antiCRISPR protein AcrIIA1 induces degradation of #Cas9 in human cells #PLOSBiology plos.io/3uUGAos

  24. Scientists at Oak Ridge National Laboratory used their expertise in #quantum #biology, artificial intelligence and #bioengineering to improve how #CRISPR #Cas9 #genome editing tools work on #organisms like #microbes that can be modified to produce #renewable #fuels and #chemicals.
    #Biology #AI #ArtificialIntelligence #sflorg
    sflorg.com/2023/11/bio11072301

  25. Scientists at Oak Ridge National Laboratory used their expertise in #quantum #biology, artificial intelligence and #bioengineering to improve how #CRISPR #Cas9 #genome editing tools work on #organisms like #microbes that can be modified to produce #renewable #fuels and #chemicals.
    #Biology #AI #ArtificialIntelligence #sflorg
    sflorg.com/2023/11/bio11072301

  26. Find out what happens when Merkulov et al. combine #Cas9-targeted #Nanopore sequencing (CANS) with the novel pipeline NanoCasTE to trace both #genetically inherited and #somatic #TEIs in plants!
    doi.org/10.1111/jipb.13555
    @wileyplantsci
    #JIPB #PlantSci #Arabidopsis #PlantScience #botany

  27. They call it “#skeletal #editing” and they hope it will change their field – and our world.

    Inspired in part by the revolutionary genome-editing technology #Crispr-#Cas9, Levin and Sarpong are among a handful of chemists developing new methods to #insert, #delete and #swap individual atoms within molecules.

    The word “editing” evokes chemists altering atoms with pairs of nanoscopic tweezers, but that would be far from efficient. “If you wanted to make a mole,” Levin explains, referring to a unit of measurement used in chemistry, “you would have to take that pair of tweezers and do it 10^23 times.”

    theguardian.com/science/2023/a

  28. They call it “#skeletal #editing” and they hope it will change their field – and our world.

    Inspired in part by the revolutionary genome-editing technology #Crispr-#Cas9, Levin and Sarpong are among a handful of chemists developing new methods to #insert, #delete and #swap individual atoms within molecules.

    The word “editing” evokes chemists altering atoms with pairs of nanoscopic tweezers, but that would be far from efficient. “If you wanted to make a mole,” Levin explains, referring to a unit of measurement used in chemistry, “you would have to take that pair of tweezers and do it 10^23 times.”

    theguardian.com/science/2023/a

  29. On this day in 2005: CRISPR noted to provide immunity and degrade DNA as means to prevent infection #CRISPR #Cas9 #ThisDayInBiotech

  30. On this day in 2005: CRISPR noted to provide immunity and degrade DNA as means to prevent infection #CRISPR #Cas9 #ThisDayInBiotech

  31. New nanoparticles can perform gene editing in the lungs
    Using these RNA-delivery particles, researchers hope to develop new treatments for cystic fibrosis and other lung diseases. #dna #CRISPR #RNA #geneediting #nanoparticles #isogg #cas9 #geneadons #epigenetics
    news.mit.edu/2023/new-nanopart

  32. New nanoparticles can perform gene editing in the lungs
    Using these RNA-delivery particles, researchers hope to develop new treatments for cystic fibrosis and other lung diseases. #dna #CRISPR #RNA #geneediting #nanoparticles #isogg #cas9 #geneadons #epigenetics
    news.mit.edu/2023/new-nanopart

  33. Nicht selten wirken pathogene #Mutation­en über die Verschiebung des Leserasters in einem #Protein-codierenden #Gen. Auf welche Weise Frame-Editoren aus Polymerase und #Cas9-Nuklease sie künftig korrigieren könnten, beschreibt @[email protected]: 👉 laborjournal.de/editorials/266

  34. Target site preferences mean that no single #Cas9 can edit all sequences. Study identifies PI domain variants in natural SaCas9 orthologs that recognize a simple NNGG PAM; these can confer NNGG PAM recognition, expanding the #CRISPR repertoire #PLOSBiology plos.io/3gJB4OR

  35. Target site preferences mean that no single #Cas9 can edit all sequences. Study identifies PI domain variants in natural SaCas9 orthologs that recognize a simple NNGG PAM; these can confer NNGG PAM recognition, expanding the #CRISPR repertoire #PLOSBiology plos.io/3gJB4OR

  36. Target site preferences mean that no single #Cas9 can edit all sequences. Study identifies PI domain variants in natural SaCas9 orthologs that recognize a simple NNGG PAM; these can confer NNGG PAM recognition, expanding the #CRISPR repertoire #PLOSBiology plos.io/3gJB4OR

  37. Target site preferences mean that no single #Cas9 can edit all sequences. Study identifies PI domain variants in natural SaCas9 orthologs that recognize a simple NNGG PAM; these can confer NNGG PAM recognition, expanding the #CRISPR repertoire #PLOSBiology plos.io/3gJB4OR

  38. Target site preferences mean that no single #Cas9 can edit all sequences. Study identifies PI domain variants in natural SaCas9 orthologs that recognize a simple NNGG PAM; these can confer NNGG PAM recognition, expanding the #CRISPR repertoire #PLOSBiology plos.io/3gJB4OR

  39. Target site preferences mean that no single #Cas9 can edit all sequences. Study identifies PI domain variants in natural SaCas9 orthologs that recognize a simple NNGG PAM; these can confer NNGG PAM recognition, expanding the #CRISPR repertoire #PLOSBiology plos.io/3gJB4OR

  40. CW: Darf ich ein bisschen angeben?

    @lenri2017
    Ich habe 2014 die deutschsprachigen #Wikipedia-Artikel zu #EmmanuelleCharpentier und (als IP) zu #JenniferADoudna geschrieben, die für ihre Arbeiten zur #CRISPR / #Cas9 #Genschere 2020 den #Nobelpreis in #Chemie erhielten.