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#cardiosky — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #cardiosky, aggregated by home.social.

  1. RCTs have shown no benefit from IABP in acute ischemic cardiogenic shock, an observatiobal trial isn’t even hypothesis generating. No grounds for new IABP trials in this population in my opinion. #cardiosky #cccsky #emimcc

    Intra-aortic balloon pump vers...

  2. Observational studies suggests higher mortality but lower thrombosis risk with VKA vs DOACs in CTEPH. What do people do? Personally I want a trial before switching to DOACs as standard of care here #emimcc #cardiosky

  3. Bayesian reanalysis can be a great way to assess a contested trial, by showing how strong a prior you need to nullify or inverse the results. I don't understand why they did not include a pessimistic prior here though (even as I see a sceptical one more realistic). #emimcc #cardiosky #cccsky #stats

    RE: https://bsky.app/profile/did:plc:77cp7kgakti2uthqnkkdaqum/post/3mkpw474mis2q

  4. Single arm pulmonary embolism intervention studies are useless for anything than assessing adverse events, perhaps even more so than the registry studies. Just look at the discrepancy in mortality between RCTs and observational data without inclusion criteria. #emimcc #cardiosky

  5. This should be the death of Impella outside of severe cardiogenic shock. High probability it increases mortality. #cardiosky #cccsky

    RE: https://bsky.app/profile/did:plc:yrhfut7mmcbabz6mgjqcyums/post/3mi7xwmgjrs2k

  6. The end of the road for rivaroxaban? Shows how important direct comparative trials among drugs within the same pharmacologic class are. #emimcc #cardiosky www.nejm.org/doi/full/10....

  7. Is anyone aware of openly available datasets from hypertension trials? #stats #nephsky #cardiosky

  8. One thing that strikes me from these guidelines (which do have many good parts) is how many of the interventions have strong Ia recommendations based on purely observational evidence. Putting the cart before the horse #emimcc #cardiosky

    RE: https://bsky.app/profile/did:plc:pdj5upxe4ocjvjltlkdai7b4/post/3mfi3rdpwyc2t

  9. There are few absolute rules in medicine but «never treat sinus tachycardia, treat the cause» has extremely few exceptions. #emimcc #cardiosky #medsky

    RE: https://bsky.app/profile/did:plc:kgfqlfzek5twmq7ahzc5ws46/post/3megnwoheqs2q

  10. Levosimendan is quite often seen as a "safe" inodilator with respect to ventricular arrhythmias. I don't think it is, and this trial in my view supports that. Also, drugs with very long half lives are generally not a good idea in the critically ill #cardiosky #emimcc #cccsky

    Levosimendan to Facilitate Wea...

  11. New results from DanGer Shock ,shows it's those with the lower systolic pressure (the sicker patients) that benefit from Impella. #emimcc #cardiosky #cccsky jamanetwork.com/journals/jam...

  12. Fascinating paper suggesting the assumption that there is a sigmoid dose response relationship and threshold effect ( "all-or-nothing") for loop diuretics rests on repeated misinterpretation of original studies from the 70s and 80s. #nephsky #cardiosky #emimcc academic.oup.com/ehjcvp/artic...

    What are the pharmacodynamics ...

  13. Hypokalemia caused by loop diuretics, I wonder if chloride loss and ensuing metabolic alkalosis is more important than potassium loss itself? #cardiosky #nephsky #emimcc

  14. Reupping this question as I’m seeing the same, often because it is assumed to be better tolerated hemodynamically (myth?). #cardiosky #emimcc #kidneysky

    RE: https://bsky.app/profile/did:plc:kibuncmmpq2nfezzxd22ircj/post/3ljzxz4q6rk2s

  15. Finally some good evidence for whether DOACs can be effective in treatment of left ventricular thrombus. Is this generalisable to all DOACs? #cardiosky #cccsky www.jacc.org/doi/10.1016/...

    Rivaroxaban vs Warfarin in Acu...

  16. Granted, few patients where still available after 4 years, but still odd to have 0 mortality from 4 to 10 years in a population that has had cardiogneic shock #cccsky #cardiosky #emimcc

    RE: https://bsky.app/profile/did:plc:pqur3apsmhyw756zvruofulp/post/3lxp2qv4ttc2c

  17. Extremely striking difference in utilisation of Impella in the US vs UK and Canada. #cardiosky #cccsky #emimcc jamanetwork.com/journals/jam...

  18. Very interesting study comparing standard anticoagulation to Watchman atrial closure after atrial fibrillation ablation, should garner lots of discussion! Lower bleeding rates, no difference in stroke risk. #cardiosky #medsky #AHA24 www.nejm.org/doi/full/10....

    Left Atrial Appendage Closure ...