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#cardiosky — Public Fediverse posts

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  1. You cannot assess safety nor efficacy in a single arm observational trial! I don't know how these things pass editorial and peer review. #emimcc #critcaresky #cccsky #cardiosky journal.chestnet.org/article/S001...

    Efficacy and Safety of Landiol...

  2. This is the kind of question that either needs a randomised trial or a clever instrumental variable, propensity score is no better than simple adjustment. Confounding by indication and other unmeasured confounding is too strong. #nephsky #cardiosky jamanetwork.com/journals/jam...

    Oral Anticoagulants in Patient...

  3. This should be the end of routine anticoagulation after TAVI. No patient centered benefit, only harm. www.jacc.org/doi/10.1016/... #cardiosky

    Short-Term Anticoagulant Thera...

  4. Still a question of affordability and cost effectiveness. I don‘t belive we’ll be bypassing betablockers anytime soon. #cardiosky

    RE: https://bsky.app/profile/did:plc:4ishw7rkrolkkkvqvkdcdgvl/post/3mua3wq425h2y

  5. Editors should not accept for publication papers using the phrase «real world evidence». It’s a marketing term, to embellish non-causal studies. #metasci #stats #cardiosky www.ahajournals.org/doi/10.1161/...

    Stopping Oral Anticoagulation ...

  6. No benefit of vagus nerve stimulation compared to a sham procedure on PVCs. Regression to the mean, or truly a placebo effect? #cardiosky #metasci www.jacc.org/doi/10.1016/...

    Transcutaneous Electrical Vagu...

  7. As ridiculous as CKD staging is, we have nothing on this thing of utter beauty

    www.ahajournals.org/doi/10.1161/...

    We are all stage A HF! Flozinate everyone. GDMT on the drinking water.

    #medsky #cardiosky

    /s

  8. Systemic vascular resistance is not a realiable measure of left ventriclar afterload. In this study, noradrenaline actually decreased left ventricular wall stress even though SVR increased. Higher heart rate and contractility leads to a smaller LV, lower wall stress. #emimcc #cccsky #cardiosky

    Systemic vascular resistance: ...

  9. RCTs have shown no benefit from IABP in acute ischemic cardiogenic shock, an observatiobal trial isn’t even hypothesis generating. No grounds for new IABP trials in this population in my opinion. #cardiosky #cccsky #emimcc

    Intra-aortic balloon pump vers...

  10. Observational studies suggests higher mortality but lower thrombosis risk with VKA vs DOACs in CTEPH. What do people do? Personally I want a trial before switching to DOACs as standard of care here #emimcc #cardiosky

  11. Bayesian reanalysis can be a great way to assess a contested trial, by showing how strong a prior you need to nullify or inverse the results. I don't understand why they did not include a pessimistic prior here though (even as I see a sceptical one more realistic). #emimcc #cardiosky #cccsky #stats

    RE: https://bsky.app/profile/did:plc:77cp7kgakti2uthqnkkdaqum/post/3mkpw474mis2q

  12. Single arm pulmonary embolism intervention studies are useless for anything than assessing adverse events, perhaps even more so than the registry studies. Just look at the discrepancy in mortality between RCTs and observational data without inclusion criteria. #emimcc #cardiosky

  13. A diagnostic tool, that decreases all cause mortality in HFpEF? That’s fairly hard to believe. #cardiosky

    RE: https://bsky.app/profile/did:plc:ll2t32wq6gvr5zv4xdkx7qeo/post/3micakgvklt2d

  14. This should be the death of Impella outside of severe cardiogenic shock. High probability it increases mortality. #cardiosky #cccsky

    RE: https://bsky.app/profile/did:plc:yrhfut7mmcbabz6mgjqcyums/post/3mi7xwmgjrs2k

  15. Convincing evidence that there is a benefit to CTO, but still a question if it is worth the resources and costs of these long procedures. Look forward to reading the full paper, not least for the bayesian analysis. Hard to interpret without knowing the priors. #cardiosky

    RE: https://bsky.app/profile/did:plc:4ishw7rkrolkkkvqvkdcdgvl/post/3mi7ccrllka2d

  16. I really don't understand this trial. Why would you randomise STEMI patients to get Impella and wait for 30 minutes before revascularisation? Time is more important than wall tension I think. Amazed it didn't cause more harm really. #cardiosky www.jacc.org/doi/10.1016/...

    Left Ventricular Unloading in ...

  17. The most undervalued and unrecognised part of human physiology and certainly the circulatory system is the lymphatic system. #cardiosky #physiology

    RE: https://bsky.app/profile/did:plc:5yfczijh7ejvbi3zyqdpl5wm/post/3mguyneojbd2t