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#brca1 — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #brca1, aggregated by home.social.

  1. Un batterio che tutti abbiamo in bocca viaggia nel sangue, arriva al seno e accelera i tumori. Se poi hai la mutazione BRCA1, le tue cellule gli aprono la porta. Johns Hopkins ha trovato il meccanismo: e collega il dentista all'oncologo in modo inaspettato.

    futuroprossimo.it/2026/03/canc

    #futuroprossimo #BRCA1 #cancro

  2. A #transcription-independent mechanism -#RBM10-mediated RNA alternative #splicing coupled to nonsense-mediated #mRNA decay- determines rapid periodic fluctuations of #BRCA1 expression throughout the #cellcycle

    embopress.org/doi/full/10.1525

  3. Extensive multivalent interactions between intrinsically disordered regions in the #BRCA1/#BARD1 #E3 #ligase and #nucleosome substrates facilitate #chromatin recruitment and contribute to histone H2A #ubiquitylation and #DNArepair
    Sam Witus, Rachel Klevit, Weixing Zhao et al
    embopress.org/doi/10.15252/emb

  4. Mutations of #BRCA1 and #BRCA2 #genes, which are inherited by 1 in 400 and 1 in 800 people respectively, significantly increase the risk of certain cancers such as #ovarian, #breast, #pancreatic and #prostate #cancer.
    #Medical #Biology #sflorg
    sflorg.com/2022/11/med11282201