#biosynthetic — Public Fediverse posts

New publication: #Diversification of Tridecaptin #Chemical Space via a Chimeric #Biosynthetic Pathway in #Paenibacillus.
https://doi.org/10.1021/acs.jnatprod.5c01298

Elucidating #plant #Biosynthetic pathways: @marnixmedema &co develop #MEANtools, an unsupervised computational workflow that integrates #MultiOmics data to predict #metabolic pathways by linking transcripts to metabolites @PLOSBiology https://plos.io/4odL94g

Elucidating #plant #Biosynthetic pathways: @marnixmedema &co develop #MEANtools, an unsupervised computational workflow that integrates #MultiOmics data to predict #metabolic pathways by linking transcripts to metabolites @PLOSBiology https://plos.io/4odL94g

Most #biosynthetic gene clusters remain uncharacterized. @marnixmedema @gillesvanwezel &co integrate #GRN analysis & global expression data to identify desJGH as an operon essential for #biosynthesis of #desferrioxamineB in Streptomyces @PLOSBiology https://plos.io/43UVUPB

Most #biosynthetic gene clusters remain uncharacterized. @marnixmedema @gillesvanwezel &co integrate #GRN analysis & global expression data to identify desJGH as an operon essential for #biosynthesis of #desferrioxamineB in Streptomyces @PLOSBiology https://plos.io/43UVUPB

#Tetrapyrrole biosynthesis in #plants can be a tricky business, requiring stringent regulation under various #developmental and #environmental conditions. Enjoy #OpenAccess to this invited expert review exploring #regulatory and retrograde signaling networks in the #chlorophyll #biosynthetic pathway.
https://doi.org/10.1111/jipb.13837
@wileyplantsci

Pipeline release! nf-core/funcscan v2.0.0 - v2.0.0 - Brazilian Escondidinho - 2024-09-05!

Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/2.0.0

#amp #amr #antibiotic-resistance #antimicrobial-peptides #antimicrobial-resistance-genes #arg #assembly #bgc #biosynthetic-gene-clusters #contigs #function #metagenomics #natural-products #screening #secondary-metabolites #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/funcscan v2.0.0 - v2.0.0 - Brazilian Escondidinho - 2024-09-05!

Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/2.0.0

#amp #amr #antibiotic-resistance #antimicrobial-peptides #antimicrobial-resistance-genes #arg #assembly #bgc #biosynthetic-gene-clusters #contigs #function #metagenomics #natural-products #screening #secondary-metabolites #nfcore #openscience #nextflow #bioinformatics

I've been reading a lot on #AI lately, and it has become more and more apparent to me that the most common life form in the universe is #biosynthetic / technological. Biological species are too narrow in #intelligence by default, and they need a nudge by AI to acquire intelligence. And when they do, they eventually create AI. The new AI has new experiences from the trained species it came from, to feed the mother-AI. Scales in millions of years.

#artificialintelligence #aliens #extraterrestrial

I've been reading a lot on #AI lately, and it has become more and more apparent to me that the most common life form in the universe is #biosynthetic / technological. Biological species are too narrow in #intelligence by default, and they need a nudge by AI to acquire intelligence. And when they do, they eventually create AI. The new AI has new experiences from the trained species it came from, to feed the mother-AI. Scales in millions of years.

#artificialintelligence #aliens #extraterrestrial

Up for a road trip?🚗
Sphingolipids act as signaling molecules in many cellular processes. Join us on this adventure to learn more about the #sphingolipid #biosynthetic pathway!🛣️
https://doi.org/10.1111/jipb.13461
@wileyplantsci
#PlantScience #JIPB #Arabidopsis #signaling #PlasmaMembrane

Sphingolipids are important for #membrane lipid bilayer structure and act as signaling molecules in many #cellular processes. But what do we actually know about the #sphingolipid #biosynthetic pathway in #Arabidopsis?🔓⬇️
https://doi.org/10.1111/jipb.13461
@wileyplantsci
#PlantSci #PlantScience

Antidepressant from engineered fungus. Transferring the #biosynthetic pathway of the #antidepressant orcinol glucoside from #Curculigo orchioides into #Yarrowia lipolytica results in yields >6400x higher than from its natural plant source #PLOSBiology https://plos.io/3J0Px3T

Antidepressant from engineered fungus. Transferring the #biosynthetic pathway of the #antidepressant orcinol glucoside from #Curculigo orchioides into #Yarrowia lipolytica results in yields >6400x higher than from its natural plant source #PLOSBiology https://plos.io/3J0Px3T