#bioconjugation — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #bioconjugation, aggregated by home.social.
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Exciting talk by Kevin Neumann at #NWOCHAINS. He talked about the tetrazine- and triazine-thiol exchange reactions for #bioconjugation and #peptide cyclization. He also discussed their potential application for #CovalentInhibitors.
https://onlinelibrary.wiley.com/doi/full/10.1002/psc.3548
https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/ceur.202500273
#Chemistry #ChemBio #DrugDiscovery -
Interesting paper by the group of Marcos Suero in Angewandte Chemie. They developed a #bioconjugation reaction to thiols using cyclopropenium cations. The resulting product on cysteine can be further modified using a thiol-ene reaction.
https://onlinelibrary.wiley.com/doi/10.1002/anie.202518939
#Chemistry #ChemBio