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#autophagic — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #autophagic, aggregated by home.social.

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  1. The EMBO Journal @[email protected] ·

    Why is functional #autophagy important for #cardiac health?
    Abel Lab and collaborators shows that #autophagic flux controls NAD+ homeostasis in #cardiomyocytes, thereby preventing #mitochondrial dysfunction
    embopress.org/doi/full/10.1038

    #autophagy #cardiac #autophagic #cardiomyocytes #mitochondrial
  2. The EMBO Journal @[email protected] ·

    TFEB-dependent lysosome biogenesis is required for #senescence
    by Bernadette Carroll and coworkers

    Transcription factor #TFEB induces #lysosome proliferation in #senescent cells, counterbalancing reduced lysosomal efficiency and maintaining #autophagic capacity
    embopress.org/doi/10.15252/emb

    #senescence #tfeb #lysosome #senescent #autophagic
  3. The EMBO Journal @[email protected] ·

    A #protelysis cascade fine-tunes homologous #recombination repair in plants:
    Arp Schnittger and coworkers show #KNOTEN1, stabilized by #UBP12/13, triggering K63-linked #ubiquitination and #autophagic degradation of #BLM complex subunit #RMI1 upon #DNAdamage

    embopress.org/doi/10.15252/emb

    #protelysis #recombination #knoten1 #ubp12 #ubiquitination #autophagic