Even with #antiretroviral therapy, HIV-1 can still cause persistent inflammation in macrophages. This study shows that intron-containing #HIV1 RNA (icRNA) activates NLRP1 #inflammasome & induces IL-1β secretion in myeloid cells, independent of RIG-I-like receptors @PLOSBiology https://plos.io/45VTGBR
#antiretroviral — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #antiretroviral, aggregated by home.social.
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New #antiretroviral alert! A new study in #PLOSBiology reveals a novel long-acting deoxyadenosine analog, MK-8527, that displays potent antiretroviral activity and favorable preclinical pharmacokinetic and off-target profiles in non-human primate models of #HIV infection.
https://plos.io/45UfwV4 -
Five #children see #HIV viral loads vanish after taking #antiretroviral drugs
After putting children on antiretrovirals early in life to control HIV, doctors were keen to monitor progress and adherence to antiretroviral treatment, which stops HIV from replicating. Over following decade, something unusual happened. 5 children stopped coming to clinic to collect drugs, and when the team eventually tracked them down many months later, they appeared to be in perfect #health.
https://arstechnica.com/health/2025/08/five-children-see-hiv-viral-loads-vanish-after-taking-antiretroviral-drugs/ -
#British #gay #man ‘#tortured’ in #Qatar is almost out of #HIV #medicine, #family says.
#ManuelGuerrero, 44, is #banned from leaving the country and is about to run out of #antiretroviral #medication, his #brother Enrique tells #TheAdvocate.
#Women #Transgender #LGBTQ #LGBTQIA #MiddleEast #Police #Hate #Bigotry #Violence #Homophobia #HIV #AIDS
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Long-acting injectables can be a good option for people with adherence challenges | aidsmap https://www.aidsmap.com/news/mar-2024/long-acting-injectables-can-be-good-option-people-adherence-challenges “#Antiretroviral therapy (#ART) using #cabotegravir and #rilpivirine injections monthly or every other month can be an effective HIV treatment option for people who have difficulty maintaining viral suppression on daily pills due to suboptimal adherence, according to studies presented at the Conference on Retroviruses and Opportunistic Infections (CROI 2024).”
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Haiti: Anarchy, risk of famine, difficulty accessing HIV drugs
https://76crimes.com/2024/03/25/haiti-famine-and-hiv-drugs/
#LGBT #LGBTQ #LGBTrights #humanrights #LGBTQrights #Haiti #trans #antiretroviral #HIV #Caribbean
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A subset of white #blood #cells, known as #myeloid cells, can harbor #HIV in people who have been virally suppressed for years on #antiretroviral therapy, according to findings from a small study supported by the National Institutes of Health.
#Virology #Microbiology #sflorg
https://www.sflorg.com/2023/03/vi03272301.html -
MitoQ, a #mitochondrial #antioxidant that is available to the public as a #diet #supplement, was found in a mouse study to reverse the detrimental effects that #HIV and #antiretroviral therapy (#ART) have on mitochondria in the #brain, #heart, #aorta, #lungs, #kidney and #liver.
#Medical #sflorg
https://www.sflorg.com/2023/03/med03242301.html