Live and recent posts from across the Fediverse tagged #antimicrobialstewardship, aggregated by home.social.
Antimicrobial Resistance (AMR) Diagnostics Market – Strategic Insights and Forecasts, 2026-2035
Company Logo Boost ROI through rapid molecular and AI-enabled diagnostics, automated workflows, portfolio expansion, public-health partnerships, and geographic…
#NewsBeep #News #Health #AMRDiagnosticsMarket #AntimicrobialResistance #antimicrobialstewardship #BeckmanCoulter #CA #Canada #clinicallaboratories #MarketDrivers #Moleculardiagnostics #susceptibilitytesting
https://www.newsbeep.com/ca/906639/
https://www.europesays.com/it/694292/ Superbatteri nel sangue, studio italiano: nei pazienti oncologici mortalità a 30 giorni oltre il 30% #AcinetobacterMultiresistente #AntimicrobialStewardship #Bari #BloodstreamInfections #BMCInfectiousDiseases #Enterobacterales #Health #IT #Italia #Italy #KlebsiellaPneumoniaeCarbapenemase #KPC #PoliclinicoDiBari #Salute #UniversitàAldoMoro
https://www.europesays.com/it/691109/ Infezioni ortopediche, sette giorni di antibiotici possono bastare a una condizione #AntibioticoLocale #AntimicrobialStewardship #ChirurgiaOrtopedica #Health #InfezioniOrtopediche #IT #Italia #Italy #ResistenzeAntimicrobiche #Salute #StudioDiNonInferiorità #TerapiaAntibiotica #TrialSOLARIO
Oltre il “One-Size-Fits-All”: La Rivoluzione della Medicina di Precisione nella Sepsi
La sepsi e lo shock settico rappresentano da sempre una delle sfide più drammatiche e complesse della medicina d’urgenza e della terapia intensiva. Per decenni l’approccio standardizzato basato su protocolli rigidi e volumi fissi ha dominato la scena, ma oggi assistiamo a uno stallo della sopravvivenza globale. La svolta? Superare il modello terapeutico universale in favore di una medicina personalizzata al letto del paziente, capace di mappare i fenotipi clinici e biologici di ciascun individuo.
Ecco i 4 pilastri fondamentali che stanno ridefinendo la gestione della sepsi, integrando le più recenti evidenze e linee guida internazionali.
1. Gestione Emodinamica e Fluid Stewardship: Il Modello ROSE
Il dogma del carico idrico fisso (i classici 30 ml/kg) cede il passo a una strategia restrittiva e titolata. La gestione dei liquidi deve seguire una stewardship dinamica divisa in quattro fasi ben distinte, nota come Modello ROSE:
Dimentichiamo le metriche statiche come la Pressione Venosa Centrale (CVP). Oggi il monitoraggio si basa su indici dinamici ed ecografia bedside (come il protocollo VExUS) per valutare la reale congestione venosa. Inoltre, la scelta dei fluidi è netta: i cristalloidi bilanciati rappresentano la prima scelta assoluta, superando la tradizionale soluzione salina allo 0.9%, associata a un maggior rischio di acidosi ipercloremica e danno renale.
2. Decatecolaminizzazione Multimodale e Target Fenotipici
L’uso prolungato e ad alte dosi di noradrenalina comporta una tossicità non trascurabile (aritmie, ischemia miocardica, immunodepressione). Il nuovo paradigma propone una decatecolaminizzazione multimodale, ovvero l’introduzione precoce di vasopressori alternativi per ridurre il carico tossico della noradrenalina. Questo approccio è guidato da biomarcatori specifici:
3. Ottimizzazione Antimicrobica di Precisione
La terapia antibiotica deve bilanciare la massima efficacia biologica con la prevenzione delle resistenze (Stewardship):
4. Terapia Corticosteridea Personalizzata
L’uso dei corticosteroidi nella sepsi non deve essere universale, ma mirato ai fenotipi infiammatori e biologici (es. sCAP, SRS2). È fondamentale identificare e completamente evitare il trattamento nei pazienti non-responder (fenotipo SRS1), riducendo gli effetti collaterali inutili.
Il Futuro Abilitante
Il superamento definitivo del plateau di mortalità passerà attraverso i sistemi di supporto decisionale clinico basati sull’Intelligenza Artificiale (AI) e la diagnostica point-of-care di nuova generazione. L’obiettivo finale è chiaro e definitivo: “Il trattamento giusto, al paziente giusto, al momento giusto.”
Seymour, CW, Kennedy, JN, Wang, S., Chang, CCH, Elliott, JC, Xu, Z., … & Angus, DC (2019). Derivazione, validazione e potenziali implicazioni terapeutiche dei fenotipi materni e biomedici per la sepsi. JAMA , 321(20), 2003-2017. https://jamanetwork.com/journals/jama/fullarticle/2733996
QIAGEN Expands QIAstat-Dx Bloodstream Infection Testing Menu in Europe
New CE-IVDR-certified QIAstat-Dx BCID GN Plus AMR Panel detects 13 gram-negative bacterial pathogen targets and 18 antimicrobial resistance…
#Europe #EU #AMRPanel #antimicrobialresistance #antimicrobialstewardship #bacterialpathogen #bloodstreaminfection #gram-negativebacteria #InfectionControl #positivebloodcultures #QIAGEN #resistancemechanisms
https://www.europesays.com/europe/94539/
Plastic pollution and drug-resistant infections are two of the biggest crises facing humanity, but they are usually considered separately by scientists and policymakers. New research is finding deeply concerning links between them.
My latest article for Mongabay.com explores how microplastic pollution is enhancing antimicrobial resistance.
https://news.mongabay.com/2026/07/microplastic-pollution-can-fuel-rise-in-antibiotic-resistance-studies-find/ #plasticpollution #antimicrobialstewardship #drugresistance
Early Release – Recent Systemic Antifungal Exposure and Nonsusceptible Candida in Hospitalized Patients, South Africa, 2012–2017 – Volume 31, Number 10—October 2025 – Emerging Infectious Diseases journal
Disclaimer: Early release articles are not considered as final versions.…
#NewsBeep #News #Headlines #antifungalagents #antifungaldrugresistance #Antimicrobialresistance #antimicrobialstewardship #azoles #Candida #fungalinfections #fungi #Latvia #LV #SouthAfrica
https://www.newsbeep.com/143217/
Urgent Care Linked to High Prescribing Rates
TOPLINE: Urgent care visits frequently result in inappropriate prescribing, with 12.4% leading to antibiotic fills, 9.1% to glucocorti…
#NewsBeep #News #Medication #acutebronchitis #antibioticoveruse #antibiotics #antimicrobialstewardship #CA #Canada #glucocorticoid #glucocorticoidtherapy #glucocorticosteroids #Health #opioids #otitismedia #overprescribe #overprescribed #overprescribing #prescriptiondrug #urgentcare
https://www.newsbeep.com/ca/16071/
Urgent Care Linked to High Prescribing Rates
TOPLINE: Urgent care visits frequently result in inappropriate prescribing, with 12.4% leading to antibiotic fills, 9.1% to glucoco…
#NewsBeep #News #Medication #acutebronchitis #antibioticoveruse #antibiotics #antimicrobialstewardship #AU #Australia #glucocorticoid #glucocorticoidtherapy #glucocorticosteroids #Health #opioids #otitismedia #overprescribe #overprescribed #overprescribing #prescriptiondrug #urgentcare
https://www.newsbeep.com/au/13942/
Mudenda et al. found high antibiotic prescribing (72.3%) at a Zambian hospital, with most drugs (77.1%) from the WHO Access list, and recommend the implementation of #AntimicrobialStewardship programmes:
https://doi.org/10.1093/jacamr/dlae023
#IDMastodon
I know mastodon isn't really the self promoting place that the birdsite was......but I am very proud of this achievement! Last week our university (#vetmeduni #vienna) held an international conference on #veterinary #antibiotic use and #AntimicrobialStewardship for almost 100 researchers from all over Europe, USA, Canada, Argentina etc. and I virtually organised it singlehandedly! I had never organised anything like it before, but I did it, everybody loved it and told me how great it was 😁🐮🐷🐴🐶🐱
Antifungals are going the way of antibiotics—overused, hitting resistance - Enlarge / Ringworm. (credit: CDC/Getty Images)
Clinicians in t... - https://arstechnica.com/?p=1996151 #antimicrobialstewardship #fungalinfections #drugresitance #antifungal #ringworm #science #health #cdc
I'm organising an international conference (#AACTING) on #monitoring #benchmarking and #antimicrobialstewardship for #antibiotics in #veterinary #medicine at the Vetmeduni in Vienna in February. We will have lots of #veterinarians as well as the World Animal Health Organisation (WOAH/OIE) and the European Medicines Agency represented. We're all working together for #prudent #antibiotic use and #publichealth
There's still time to register and details are on our website: https://aacting.org/aacting-conferences/
Meet Sefunda during the 42nd Annual J.P. Morgan Health Care Conference! I am attending RESI JPM 2024 Conference in San Francisco from January, 9th -11th.
Meet meand learn more about Sefunda's mission to make rapid PCR testing an accessible standard for everybody.
Because "Without diagnostics, medicine is blind." - Alain Mérieux
#diagnostics #JPMorganHealth #RESI #Sefunda #antimicrobialresistance #antimicrobialstewardship #infectiousdiseases #health #healthcare #testing
People aspire to do one thing, then justify doing something completely different....
#AMS #antimicrobialstewardship https://pubmed.ncbi.nlm.nih.gov/37970680/
ESCMID guidelines on diagnosis and treatment of brain abscess in children and adults - Clinical Microbiology and Infection
#IDMastodon #MedMastodon #AMR #antibiotics #microbiology #antimicrobialstewardship #infectiousdiseases #medicine @infectiousdiseases @microbiology #brain #abscess
The hardest challenge in stewardship remains.... the people (#doctors)!
You provide point-of-care measures of bacterial infection (Biofire & PCT measurements) for patients with respiratory infection, and.... no difference in antibiotic consumption. 🤷
#AMR #AMS #antimicrobialstewardship #microbiology #IDMastodon #infectiousdeseases #medicine #antibiotics #diagnostics #ED #POC
No rest for the antimicrobial steward, even when out for an ice cream! 🍦
#AMS #IDMastodon #MedMastodon #AMR #antibiotics #microbiology #antimicrobialstewardship #Creams
🆕 Episode of #Breakpoints
Drs. Zack Nelson, Alison Dittmer, and Michael Pulia join Dr. Jillian Hayes to discuss the ins and outs of #antimicrobialstewardship in one of the busiest parts of the hospital: the emergency department!
🎧 Listen now: https://sidp.pinecast.co/
Reminder of the resources needed to control #AMR and how #war in #Ukraine will impact this locally and probably also beyond the conflict areas.
Ukraine war and antimicrobial resistance - The Lancet Infectious Diseases #antibiotics #microbiology #antimicrobialstewardship
Do you love #AntimicrobialStewardship and CE credits? ♥️🦠
Check out this on-demand webcast worth 0.125 CEUs! Expanding the Impact of Antimicrobial Stewardship: Expert Roundtable with Elizabeth Dodds-Ashley, PharmD, MHS, FCCP, FSIDP, BCPS, Kerry LaPlante, PharmD, FCCP, FIDSA, FIDP, Elizabeth Monsees, PhD, RN, CIC, FAPIC and Arjun Srinivasan, MD!
Watch it here: https://bit.ly/3IHPOYl
#IDMastodon #TooteRx #IDTooter #MastodonRx
Be sure to watch this on-demand webcast! Expanding the Impact of #AntimicrobialStewardship: Expert Roundtable with Elizabeth Dodds-Ashley, PharmD, MHS, FCCP, FSIDP, BCPS, Kerry LaPlante, PharmD, FCCP, FIDSA, FIDP, Elizabeth Monsees, PhD, RN, CIC, FAPIC and Arjun Srinivasan, MD
Check it out: https://bit.ly/3IHPOYl
#IDMastodon #TooteRx #IDTooter #MastodonRx
Elderly and catheterized patients have a high incidence of asymptomatic bacteriuria. Abnormal UA in asymptomatic patient does NOT necessarily require treatment.
#AsymptomaticBacteriuria #medicine #MedMastodon #IDMastodon #IMPearls #AntimicrobialStewardship #AntimicrobialResistance
Symptoms that do NOT warrant investigation for #UTI include change in the color, odor, or consistency of the urine
#MedMastodon #IDMastodon #IMPearls #MedEd #medicine #AntimicrobialStewardship
Diagnosing invasive fungal infections is hard. This review will help.
#IDMastodon #fungal #fungi #FungiFriday #diagnostics #AMR #antimicrobialstewardship
When medical visits are shorter, patients more likely to get unneeded antibiotics
Even as a young #pediatric resident in the 1980s it became obvious to me that it was much quicker to write an #antibiotic Rx than to explain to patients/parents why an antibiotic wasn’t needed. Sadly, too many beleaguered providers choose the former. #healthcare #AntimicrobialStewardship #PatientCare #AntibioticOveruse #medicine
I played a bit with ChatGPT this morning, assuming I'd get similar results to Stable Diffusion's image generation, i.e. initially convincing, but overall low quality.
That...is not what I got. I asked it to write an email about antibiotics and it did a pretty good job.
Prompt: "Write an email convincing a surgeon to reduce antibiotic prophylaxis from 32 hours to 24 hours as per microbiology guidance."
🧵...
Intriguing: a risk score for identifying patients at low risk of bacterial meningitis. This is always an issue and with real #antimicrobialstewardship opportunity #AMR
#IDMastodon #MedMastodon
Important study in a challenging population - UTI in the elderly.
**Less antibiotics prescribed & no worse outcomes**
My worry with these behaviour / feedback based stewardship interventions is how sustainable the change in practice is once the study has finished.
#IDMastodon #MedMastodon #AMR #antibiotics #microbiology #antimicrobialstewardship #AMS
Came across this old(ish) #antimicrobialstewardship paper again tonight.
Important message - not all interventions acceptable / implemented.
Making advice more palatable is key, otherwise = Abx reviews are wasted effort! #IDMastodon https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(20)30476-6/fulltext#:~:text=Antibiotics%3A%20easier%20to%20start%20than%20to%20stop%3F%20Predictors,drivers%20of%20recommendation%20acceptance%20are%20not%20well%20understood.
Is penicillin allergy de-labelling about to find its place in UK antimicrobial stewardship strategy? | RCP Journals
https://www.rcpjournals.org/content/clinmedicine/23/1/76
#microbiology #penicillinallergy #IDMastodon #MedMastodon #antimicrobialstewardship #AMR
Provocative piece. Lots of AMS activity, but still a rise in total antimicrobial prescribing. Is this a failure?
Likely these statistics too coarse at population level to answer that question, but food for thought in this article ...
https://academic.oup.com/jac/article/75/5/1087/5739987#.XkxHTtyEct8.twitter
#AMR #antimicrobialstewardship #IDMastodon #antibiotics
A systematic review of systematic reviews looking at antimicrobial stewardship outcomes reported.
Unsurprisingly .... 𝗵𝗲𝘁𝗲𝗿𝗼𝗴𝗲𝗻𝗲𝗶𝘁𝘆 +++
#AMR #microbiology #AMS #antimicrobialstewardship #antibiotics #review #IDMastodon #MedMastodon #academia
Infectious disease forecasting is vital for epidemic and pandemic preparedness – but current models leave something to be desired. Could incorporating genetics, genomics, and phylodynamics close the accuracy gap?
https://thepathologist.com/outside-the-lab/a-weather-forecast-for-disease
#genetics #genomics #phylogenetics #phylogenomics #phylodynamics #epidemiology #IDMastodon #Infectious Disease #AntimicrobialResistance #AntimicrobialStewardship
A sepsis intervention bundle that increases antimicrobial use without improving outcomes! 😔
This Viewpoint suggests changing the focus of sepsis quality metrics from processes to outcomes.
#sepsis #IDMastodon #icu #criticalcare #MedMastodon #AMR #antibiotics #microbiology #antimicrobialstewardship
Sepsis and antibiotics: When should we deploy a parachute?
Reminder there is never really a right answer but there is always space for more research!
#IDMastodon #MedMastodon #AMR #antibiotics #microbiology #antimicrobialstewardship #sepsis #academia #infection
https://www.sciencedirect.com/science/article/abs/pii/S0924857923000201
Age old argument. Most isolates susceptible to tebipenem because it's not available.
Will it stay that way if licensed and prescribed freely in the community?
#AMR #antibiotics #microbiology #antimicrobialstewardship #tebipenem #carbapenems
Antimicrobial Activity of Tebipenem and Comparators against Enterobacterales from diverse Outpatient Centers and Nursing Homes in the United States
https://www.sciencedirect.com/science/article/abs/pii/S0924857923000213
Complex appendicitis? ✅
Laparoscopic appendicectomy? ✅
How long to give post-op antibiotics? 🤔
🌟New 15-centre RCT indicates 2 days is just about as good as 5 days. @thelancet #AMR #AntimicrobialResistance #antimicrobialstewardship #IDmastodon #MedMastodon #academia #RCT #surgery #antibiotics
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)02588-0/fulltext?dgcid=raven_jbs_aip_email#%20 (1/3)
More cotrimoxazole use as prophylaxis in people living with HIV (PLWHIV) 👉 more cotrimoxazole resistance.
Predictable but important reminder that even justified antibiotic consumption has consequences. 🎯
🌟 Use antibiotics wisely! 🌟
#IDMastodon #AMR #MedMastodon #antimicrobialstewardship #septrin #bactrim #cotrimoxazole #HIV
https://academic.oup.com/cid/advance-article-abstract/doi/10.1093/cid/ciac978/6968505
The @SIDPharm Education Committee is excited to announce that SIDP has teamed up Center for Infectious Disease Research and Policy (CIDRAP) to discuss #AntimicrobialStewardship from a Global Aspect!
This on-demand webinar offers FREE ACPE credit and features SIDP’s very own Elizabeth Dodds Ashley, PharmD
Register now! http://bit.ly/3XmFv2f
Shamelessly learnt this on twitter, and sharing here for #IDMastodon community.
Increase water 💦 intake to prevent recurrent UTI in pre-menopausal women.
Super cheap intervention, and no #antibiotics !!!
#MedMastodon #AMR #antimicrobialstewardship #UTI
https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2705079
I had never heard of melatonin as a way to prevent renal injury with colistin!
Didn't work in this RCT, although stopped early as ran out of colistin during #COVID19! 😔
#IDMastodon #AMR #antibiotics #antimicrobialstewardship #Renal #Colistin #PolymixinB
2 common things of note in this #mpox cohort:
1) pain
2) secondary bacterial infections
#AMR #antimicrobialstewardship #antibiotics #pain #IDMastodon #MedMastodon
https://www.sciencedirect.com/science/article/pii/S1473309922008064
Meta-analysis of feedback approaches that most impact antibiotic prescribing.
Top = information about health consequences
#AMR #antimicrobialstewardship #IDMastodon #MedMastodon
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00720-4/fulltext
Delabel, delabel, delabel (penicillin allergy safely)
#AMR #antimicrobialstewardship #antibiotics #penicillin #allergy #IDMastodon #MedMastodon
https://www.ijidonline.com/article/S1201-9712(22)00617-8/fulltext
Once a week rezafungin therapy for candidaemia and invasive candidiasis.
Looks mostly non - inferior to caspofungin.
But do we need once a week antifungal therapy? Most of these patients need close observation - look at mortality below. (tho there will rare exceptions for whom this is the perfect drug).
#antifungals #AMR #antimicrobialstewardship #IDMastodon #MedMastodon @thelancet
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)02324-8/fulltext#%20
Interesting paper using genomics and epidemiology showing translocation of Pseudomonas from the gut to lungs of a ICU patient.
Crucially, this carried meropenem resistance genes between the 2 compartments
An elegant demonstration of a process we know occurs (e.g. micro-aspiration of gut content in these patients) and an excellent reminder of need to minimise antibiotic prescriptions.
#AMR #antimicrobialstewardship #WAAW2022 #IDMastodon #microbiology #MedMastodon
Important we consider how resistance is selected for these new antibiotics. Need to make them last!
#AMR #cefiderocol #antibiotics #IDMastodon #MedMastodon #cysticfibrosis #antimicrobialstewardship #WAAW2022
If you missed our special open-access #WAAW2022 webinar last night on #AntimicrobialStewardship, the recording is now available on the ESCMID eAcademy here: http://ow.ly/S36Z50LLNq2
My belated #introduction (1/5):
My career at BJC HealthCare / BJH included #antimicrobialstewardship; #infectiousdiseases #pharmacotherapy; #vaccines; #medicationsafety; patient care; #teaching; research; administrative stuff.
Former editor BJH Tool Book on the #Dorsata platform.
Still doing human research review with the #IRB and #genetherapy studies review with the IBC at WUSM.
Lastly in addition to science, I believe in democracy, the important role of journalism, and a round Earth.
JAC-Antimicrobial Resistance (JAC-AMR) is a fully #OpenAccess :oa: Society journal from the British Society for Antimicrobial Chemotherapy (BSAC).
https://academic.oup.com/jacamr
We publish original research articles, reviews, clinically oriented viewpoints, debates, brief reports and reviews of educational resources with a focus on #AntimicrobialResistance, #AntimicrobialStewardship and use relating to antibacterial, antifungal, antiviral and antiprotozoal agents
#JACAMRNews
