#antimicrobialpeptides — Public Fediverse posts

https://www.europesays.com/ie/660483/ Ancient Lactoferrin Proteins Could Produce New Drugs #AntibioticResistance #AntimicrobialPeptides #Éire #Evolution #IE #Ireland #Science

Pipeline release! nf-core/funcscan v4.0.0 - v4.0.0 - Chinese Baozi - 2026-06-27!
(Meta-)genome screening for functional and natural product gene sequences
Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/4.0.0

#amp #amr #antibioticresistance #antimicrobialpeptides #antimicrobialresistancegenes #arg #assembly #bgc #biosyntheticgeneclusters #contigs #function #metagenomics #naturalproducts #screening #secondarymetabolites #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/funcscan v4.0.0 - v4.0.0 - Chinese Baozi - 2026-06-27!
(Meta-)genome screening for functional and natural product gene sequences
Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/4.0.0

#amp #amr #antibioticresistance #antimicrobialpeptides #antimicrobialresistancegenes #arg #assembly #bgc #biosyntheticgeneclusters #contigs #function #metagenomics #naturalproducts #screening #secondarymetabolites #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/funcscan v4.0.0 - v4.0.0 - Chinese Baozi - 2026-06-27!
(Meta-)genome screening for functional and natural product gene sequences
Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/4.0.0

#amp #amr #antibioticresistance #antimicrobialpeptides #antimicrobialresistancegenes #arg #assembly #bgc #biosyntheticgeneclusters #contigs #function #metagenomics #naturalproducts #screening #secondarymetabolites #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/funcscan v4.0.0 - v4.0.0 - Chinese Baozi - 2026-06-27!
(Meta-)genome screening for functional and natural product gene sequences
Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/4.0.0

#amp #amr #antibioticresistance #antimicrobialpeptides #antimicrobialresistancegenes #arg #assembly #bgc #biosyntheticgeneclusters #contigs #function #metagenomics #naturalproducts #screening #secondarymetabolites #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/funcscan v3.0.0 - v3.0.0 - French Chocolatine - 2025-10-04!

Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/3.0.0

#amp #amr #antibioticresistance #antimicrobialpeptides #antimicrobialresistancegenes #arg #assembly #bgc #biosyntheticgeneclusters #contigs #function #metagenomics #naturalproducts #screening #secondarymetabolites #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/funcscan v3.0.0 - v3.0.0 - French Chocolatine - 2025-10-04!

Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/3.0.0

#amp #amr #antibioticresistance #antimicrobialpeptides #antimicrobialresistancegenes #arg #assembly #bgc #biosyntheticgeneclusters #contigs #function #metagenomics #naturalproducts #screening #secondarymetabolites #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/funcscan v3.0.0 - v3.0.0 - French Chocolatine - 2025-10-04!

Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/3.0.0

#amp #amr #antibioticresistance #antimicrobialpeptides #antimicrobialresistancegenes #arg #assembly #bgc #biosyntheticgeneclusters #contigs #function #metagenomics #naturalproducts #screening #secondarymetabolites #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/funcscan v3.0.0 - v3.0.0 - French Chocolatine - 2025-10-04!

Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/3.0.0

#amp #amr #antibioticresistance #antimicrobialpeptides #antimicrobialresistancegenes #arg #assembly #bgc #biosyntheticgeneclusters #contigs #function #metagenomics #naturalproducts #screening #secondarymetabolites #nfcore #openscience #nextflow #bioinformatics

🦠 What makes antimicrobial peptides so selective against bacteria and cancer cells, while leaving healthy cells intact?

🔗 Unlocking the specificity of antimicrobial peptide interactions for membrane-targeted therapies. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2024.04.022

📚 CSBJ Nanoscience & Advanced Materials: https://csbj.org/nano

#AntimicrobialPeptides #DrugDiscovery #MolecularDynamics #Biophysics #MembraneBiology #Bioinformatics #PeptideTherapeutics

Secondly, the high temperature + the infection induce #AntimicrobialPeptides in the fly, which are taken up by the parasites (the host is the only food source) and which heavily disturb the #Microbiome of the wasps. This disturbance leads to the death of the wasps (~1% of the wasps emerge vs. 44-83% at low temperatures). They also simply over expressed the #AMP:s in flies, without the temperature effect and got similar results.

Some extraordinary news for the lab just dropped, we need sometime for full disclosure

...err, we also got two papers published:

#CheesyFungi new shades of blue produced by crossing domesticated chees-making fungi @PLOS
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1011669

#CoEvoSymb a kingdom wide search for #AntimicrobialPeptides transporters
https://www.microbiologyresearch.org/content/journal/mgen/10.1099/mgen.0.001380

Some extraordinary news for the lab just dropped, we need sometime for full disclosure

...err, we also got two papers published:

#CheesyFungi new shades of blue produced by crossing domesticated chees-making fungi @PLOS
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1011669

#CoEvoSymb a kingdom wide search for #AntimicrobialPeptides transporters
https://www.microbiologyresearch.org/content/journal/mgen/10.1099/mgen.0.001380

Pipeline release! nf-core/funcscan v2.1.0 - v2.1.0 - Egyptian Koshari - 2025-03-05!

Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/2.1.0

#amp #amr #antibioticresistance #antimicrobialpeptides #antimicrobialresistancegenes #arg #assembly #bgc #biosyntheticgeneclusters #contigs #function #metagenomics #naturalproducts #screening #secondarymetabolites #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/funcscan v2.1.0 - v2.1.0 - Egyptian Koshari - 2025-03-05!

Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/2.1.0

#amp #amr #antibioticresistance #antimicrobialpeptides #antimicrobialresistancegenes #arg #assembly #bgc #biosyntheticgeneclusters #contigs #function #metagenomics #naturalproducts #screening #secondarymetabolites #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/funcscan v2.1.0 - v2.1.0 - Egyptian Koshari - 2025-03-05!

Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/2.1.0

#amp #amr #antibioticresistance #antimicrobialpeptides #antimicrobialresistancegenes #arg #assembly #bgc #biosyntheticgeneclusters #contigs #function #metagenomics #naturalproducts #screening #secondarymetabolites #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/funcscan v2.1.0 - v2.1.0 - Egyptian Koshari - 2025-03-05!

Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/2.1.0

#amp #amr #antibioticresistance #antimicrobialpeptides #antimicrobialresistancegenes #arg #assembly #bgc #biosyntheticgeneclusters #contigs #function #metagenomics #naturalproducts #screening #secondarymetabolites #nfcore #openscience #nextflow #bioinformatics

Could #antimicrobial peptides get around the threat of #antibiotic resistance #AMR? This study shows that random peptide mixtures are better than trad single-sequence #AntimicrobialPeptides at avoiding evolution of resistance in #Pseudomonas #PLOSBiology https://plos.io/3L9W9NO

Could #antimicrobial peptides get around the threat of #antibiotic resistance #AMR? This study shows that random peptide mixtures are better than trad single-sequence #AntimicrobialPeptides at avoiding evolution of resistance in #Pseudomonas #PLOSBiology https://plos.io/3L9W9NO

Could #antimicrobial peptides get around the threat of #antibiotic resistance #AMR? This study shows that random peptide mixtures are better than trad single-sequence #AntimicrobialPeptides at avoiding evolution of resistance in #Pseudomonas #PLOSBiology https://plos.io/3L9W9NO

Could #antimicrobial peptides get around the threat of #antibiotic resistance #AMR? This study shows that random peptide mixtures are better than trad single-sequence #AntimicrobialPeptides at avoiding evolution of resistance in #Pseudomonas #PLOSBiology https://plos.io/3L9W9NO

Another hot-off-the-press preprint on #Drosophila host - #microbiome interactions:

Lactobacillus plantarum is resistant to host #antimicrobialpeptides (AMPs) thanks to characteristics of its peptidoglycan that make its cell wall less sensitive to AMPs than other #bacteria. 🦠

Definitely adding to my reading list! Congrats to Aranzazu et al. and Igor Iatsenko, whose new lab has been knocking it out of the park! ⚾

https://www.biorxiv.org/content/10.1101/2023.03.21.533593v1

Another hot-off-the-press preprint on #Drosophila host - #microbiome interactions:

Lactobacillus plantarum is resistant to host #antimicrobialpeptides (AMPs) thanks to characteristics of its peptidoglycan that make its cell wall less sensitive to AMPs than other #bacteria. 🦠

Definitely adding to my reading list! Congrats to Aranzazu et al. and Igor Iatsenko, whose new lab has been knocking it out of the park! ⚾

https://www.biorxiv.org/content/10.1101/2023.03.21.533593v1

Another hot-off-the-press preprint on #Drosophila host - #microbiome interactions:

Lactobacillus plantarum is resistant to host #antimicrobialpeptides (AMPs) thanks to characteristics of its peptidoglycan that make its cell wall less sensitive to AMPs than other #bacteria. 🦠

Definitely adding to my reading list! Congrats to Aranzazu et al. and Igor Iatsenko, whose new lab has been knocking it out of the park! ⚾

https://www.biorxiv.org/content/10.1101/2023.03.21.533593v1

🦠 I'm happy to present a new nf-core pipeline for people interested in functional analysis of #MicrobialGenomes / #Metagenomes / #Microbiomes !

If you're interested in mining metagenomes for functional groups such as #AntiMicrobialResistance genes, #AntiMicrobialPeptides or #BiosyntheticGeneClusters, @nf_core /funcscan automates the screening of such sequences from input contigs or genomes in a highly parallelised, portable, and reproducible manner

https://genomic.social/@nf_core@mstdn.science/109868600236675816 🧵 [1/2]

🦠 I'm happy to present a new nf-core pipeline for people interested in functional analysis of #MicrobialGenomes / #Metagenomes / #Microbiomes !

If you're interested in mining metagenomes for functional groups such as #AntiMicrobialResistance genes, #AntiMicrobialPeptides or #BiosyntheticGeneClusters, @nf_core /funcscan automates the screening of such sequences from input contigs or genomes in a highly parallelised, portable, and reproducible manner

https://genomic.social/@nf_core@mstdn.science/109868600236675816 🧵 [1/2]

🦠 I'm happy to present a new nf-core pipeline for people interested in functional analysis of #MicrobialGenomes / #Metagenomes / #Microbiomes !

If you're interested in mining metagenomes for functional groups such as #AntiMicrobialResistance genes, #AntiMicrobialPeptides or #BiosyntheticGeneClusters, @nf_core /funcscan automates the screening of such sequences from input contigs or genomes in a highly parallelised, portable, and reproducible manner

https://genomic.social/@nf_core@mstdn.science/109868600236675816 🧵 [1/2]

🦠 I'm happy to present a new nf-core pipeline for people interested in functional analysis of #MicrobialGenomes / #Metagenomes / #Microbiomes !

If you're interested in mining metagenomes for functional groups such as #AntiMicrobialResistance genes, #AntiMicrobialPeptides or #BiosyntheticGeneClusters, @nf_core /funcscan automates the screening of such sequences from input contigs or genomes in a highly parallelised, portable, and reproducible manner

https://genomic.social/@nf_core@mstdn.science/109868600236675816 🧵 [1/2]

Happy to announce this #preprint , the culmination of last 10 years. 🥳

We find that #antimicrobialpeptides are evolved to control specific #microbiome #bacteria. This example is a textbook case of host #immune #evolution being shaped by the microbiome 🦠 which depends on host #ecology.

Thanks for comments! Bit of an experiment: we are posting pre-submit to get feedback 🙂.

https://www.biorxiv.org/content/10.1101/2022.12.23.521774v2.full
#immunity #Drosophila #EvolutionaryBiology #inflammation #NFkB

Happy to announce this #preprint , the culmination of last 10 years. 🥳

We find that #antimicrobialpeptides are evolved to control specific #microbiome #bacteria. This example is a textbook case of host #immune #evolution being shaped by the microbiome 🦠 which depends on host #ecology.

Thanks for comments! Bit of an experiment: we are posting pre-submit to get feedback 🙂.

https://www.biorxiv.org/content/10.1101/2022.12.23.521774v2.full
#immunity #Drosophila #EvolutionaryBiology #inflammation #NFkB

Happy to announce this #preprint , the culmination of last 10 years. 🥳

We find that #antimicrobialpeptides are evolved to control specific #microbiome #bacteria. This example is a textbook case of host #immune #evolution being shaped by the microbiome 🦠 which depends on host #ecology.

Thanks for comments! Bit of an experiment: we are posting pre-submit to get feedback 🙂.

https://www.biorxiv.org/content/10.1101/2022.12.23.521774v2.full
#immunity #Drosophila #EvolutionaryBiology #inflammation #NFkB

"On taking a blood meal, mosquitoes with the modification produce two antimicrobial peptides (AMPs) in the gut, which impair the malaria parasite’s development. The two peptides are magainin 2, which was first found within skin secretions of the African claw frog Xenopus laevis, and melittin, a primary toxin component of the European honey bee Apis mellifera." #malaria, #antimicrobialpeptides #genedrive

https://www.genengnews.com/topics/translational-medicine/infectious-diseases/genetically-modified-mosquitoes-stunt-malaria-parasite-growth-prevent-transmission/?MailingID=%DEPLOYMENTID%&utm_medium=newsletter&utm_source=GEN+Daily+News+Highlights&utm_content=01&utm_campaign=GEN+Daily+News+Highlights_20221226&oly_enc_id=6688E2244356C6Z

https://www.biorxiv.org/content/10.1101/2022.08.24.504952v2

Our study on intrinsic effects of #antimicrobialpeptides to healthy #aging has now been reviewed by Review Commons! You can find the reviews via TRiP and our response letter (✅ in tabs on bioRxiv). Reviewers commented on a lack of sex-specific effect discussion, which I think makes for a great thread topic 🧵:

“Your scientists were so preoccupied with whether or not they could, they didn't stop to think if they should.”
#immunity #inflammation

https://www.biorxiv.org/content/10.1101/2022.08.24.504952v2

Our study on intrinsic effects of #antimicrobialpeptides to healthy #aging has now been reviewed by Review Commons! You can find the reviews via TRiP and our response letter (✅ in tabs on bioRxiv). Reviewers commented on a lack of sex-specific effect discussion, which I think makes for a great thread topic 🧵:

“Your scientists were so preoccupied with whether or not they could, they didn't stop to think if they should.”
#immunity #inflammation

https://www.biorxiv.org/content/10.1101/2022.08.24.504952v2

Our study on intrinsic effects of #antimicrobialpeptides to healthy #aging has now been reviewed by Review Commons! You can find the reviews via TRiP and our response letter (✅ in tabs on bioRxiv). Reviewers commented on a lack of sex-specific effect discussion, which I think makes for a great thread topic 🧵:

“Your scientists were so preoccupied with whether or not they could, they didn't stop to think if they should.”
#immunity #inflammation

https://www.biorxiv.org/content/10.1101/2022.08.24.504952v2

Our study on intrinsic effects of #antimicrobialpeptides to healthy #aging has now been reviewed by Review Commons! You can find the reviews via TRiP and our response letter (✅ in tabs on bioRxiv). Reviewers commented on a lack of sex-specific effect discussion, which I think makes for a great thread topic 🧵:

“Your scientists were so preoccupied with whether or not they could, they didn't stop to think if they should.”
#immunity #inflammation

1st post #introduction. Evolutionary Biologist by training, with interests in #MolecularEcology #ornithology #InnateImmunity #AntimicrobialPeptides and #microbiology to name a few. The #SarsCoV2 #pandemic changed the world in a lot of ways, and for me it meant a career shift to #wastewater based #epidemiology (#WBE) and #viral #evolution based at #ESR in #Aotearoa, #NewZealand #COVID #viruses #InfectiousDisease #EvolutionaryBiology

1st post #introduction. Evolutionary Biologist by training, with interests in #MolecularEcology #ornithology #InnateImmunity #AntimicrobialPeptides and #microbiology to name a few. The #SarsCoV2 #pandemic changed the world in a lot of ways, and for me it meant a career shift to #wastewater based #epidemiology (#WBE) and #viral #evolution based at #ESR in #Aotearoa, #NewZealand #COVID #viruses #InfectiousDisease #EvolutionaryBiology

1st post #introduction. Evolutionary Biologist by training, with interests in #MolecularEcology #ornithology #innateimmunity #AntimicrobialPeptides and #microbiology to name a few. The #SarsCoV2 #pandemic changed the world in a lot of ways, and for me it meant a career shift to #wastewater based #epidemiology (#WBE) and #viral #evolution based at #ESR in #Aotearoa, #NewZealand #COVID #viruses #InfectiousDisease #EvolutionaryBiology

1st post #introduction. Evolutionary Biologist by training, with interests in #MolecularEcology #ornithology #innateimmunity #AntimicrobialPeptides and #microbiology to name a few. The #SarsCoV2 #pandemic changed the world in a lot of ways, and for me it meant a career shift to #wastewater based #epidemiology (#WBE) and #viral #evolution based at #ESR in #Aotearoa, #NewZealand #COVID #viruses #InfectiousDisease #EvolutionaryBiology

In the past I've worked on many other questions, including the evolution of #AntimicrobialPeptides in #frogs and the genetic basis of #SexDifferences in #strawberries.
🐸 🍓