#antimicrobialpeptides — Public Fediverse posts

Pipeline release! nf-core/funcscan v4.0.0 - v4.0.0 - Chinese Baozi - 2026-06-27!
(Meta-)genome screening for functional and natural product gene sequences
Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/4.0.0

#amp #amr #antibioticresistance #antimicrobialpeptides #antimicrobialresistancegenes #arg #assembly #bgc #biosyntheticgeneclusters #contigs #function #metagenomics #naturalproducts #screening #secondarymetabolites #nfcore #openscience #nextflow #bioinformatics

Pipeline release! nf-core/funcscan v3.0.0 - v3.0.0 - French Chocolatine - 2025-10-04!

Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/3.0.0

#amp #amr #antibioticresistance #antimicrobialpeptides #antimicrobialresistancegenes #arg #assembly #bgc #biosyntheticgeneclusters #contigs #function #metagenomics #naturalproducts #screening #secondarymetabolites #nfcore #openscience #nextflow #bioinformatics

Some extraordinary news for the lab just dropped, we need sometime for full disclosure

...err, we also got two papers published:

#CheesyFungi new shades of blue produced by crossing domesticated chees-making fungi @PLOS
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1011669

#CoEvoSymb a kingdom wide search for #AntimicrobialPeptides transporters
https://www.microbiologyresearch.org/content/journal/mgen/10.1099/mgen.0.001380

Pipeline release! nf-core/funcscan v2.1.0 - v2.1.0 - Egyptian Koshari - 2025-03-05!

Please see the changelog: https://github.com/nf-core/funcscan/releases/tag/2.1.0

#amp #amr #antibioticresistance #antimicrobialpeptides #antimicrobialresistancegenes #arg #assembly #bgc #biosyntheticgeneclusters #contigs #function #metagenomics #naturalproducts #screening #secondarymetabolites #nfcore #openscience #nextflow #bioinformatics

Could #antimicrobial peptides get around the threat of #antibiotic resistance #AMR? This study shows that random peptide mixtures are better than trad single-sequence #AntimicrobialPeptides at avoiding evolution of resistance in #Pseudomonas #PLOSBiology https://plos.io/3L9W9NO

Another hot-off-the-press preprint on #Drosophila host - #microbiome interactions:

Lactobacillus plantarum is resistant to host #antimicrobialpeptides (AMPs) thanks to characteristics of its peptidoglycan that make its cell wall less sensitive to AMPs than other #bacteria. 🦠

Definitely adding to my reading list! Congrats to Aranzazu et al. and Igor Iatsenko, whose new lab has been knocking it out of the park! ⚾

https://www.biorxiv.org/content/10.1101/2023.03.21.533593v1

🦠 I'm happy to present a new nf-core pipeline for people interested in functional analysis of #MicrobialGenomes / #Metagenomes / #Microbiomes !

If you're interested in mining metagenomes for functional groups such as #AntiMicrobialResistance genes, #AntiMicrobialPeptides or #BiosyntheticGeneClusters, @nf_core /funcscan automates the screening of such sequences from input contigs or genomes in a highly parallelised, portable, and reproducible manner

https://genomic.social/@nf_core@mstdn.science/109868600236675816 🧵 [1/2]

Happy to announce this #preprint , the culmination of last 10 years. 🥳

We find that #antimicrobialpeptides are evolved to control specific #microbiome #bacteria. This example is a textbook case of host #immune #evolution being shaped by the microbiome 🦠 which depends on host #ecology.

Thanks for comments! Bit of an experiment: we are posting pre-submit to get feedback 🙂.

https://www.biorxiv.org/content/10.1101/2022.12.23.521774v2.full
#immunity #Drosophila #EvolutionaryBiology #inflammation #NFkB

https://www.biorxiv.org/content/10.1101/2022.08.24.504952v2

Our study on intrinsic effects of #antimicrobialpeptides to healthy #aging has now been reviewed by Review Commons! You can find the reviews via TRiP and our response letter (✅ in tabs on bioRxiv). Reviewers commented on a lack of sex-specific effect discussion, which I think makes for a great thread topic 🧵:

“Your scientists were so preoccupied with whether or not they could, they didn't stop to think if they should.”
#immunity #inflammation

1st post #introduction. Evolutionary Biologist by training, with interests in #MolecularEcology #ornithology #InnateImmunity #AntimicrobialPeptides and #microbiology to name a few. The #SarsCoV2 #pandemic changed the world in a lot of ways, and for me it meant a career shift to #wastewater based #epidemiology (#WBE) and #viral #evolution based at #ESR in #Aotearoa, #NewZealand #COVID #viruses #InfectiousDisease #EvolutionaryBiology