#antigenic — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #antigenic, aggregated by home.social.
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Mechanistic and #antigenic boundaries of #Henipavirus and Parahenipavirus #glycoproteins, https://etidiohnew.blogspot.com/2026/06/mechanistic-and-antigenic-boundaries-of.html
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Mechanistic and #antigenic boundaries of #Henipavirus and Parahenipavirus #glycoproteins, https://etidiohnew.blogspot.com/2026/06/mechanistic-and-antigenic-boundaries-of.html
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#Antigenic mapping of #H2 #influenza viruses recognized by #ferret and #human sera and predicting antigenically significant sites, https://etidiohnew.blogspot.com/2026/06/antigenic-mapping-of-h2-influenza.html
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#Antigenic mapping of #H2 #influenza viruses recognized by #ferret and #human sera and predicting antigenically significant sites, https://etidiohnew.blogspot.com/2026/06/antigenic-mapping-of-h2-influenza.html
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A Panel of #Human Monoclonal #Antibodies for Tracking the #Antigenic #Evolution of #Influenza #H5N1 Clade 2.3.4.4b, https://etidiohnew.blogspot.com/2026/05/a-panel-of-human-monoclonal-antibodies.html
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A Panel of #Human Monoclonal #Antibodies for Tracking the #Antigenic #Evolution of #Influenza #H5N1 Clade 2.3.4.4b, https://etidiohnew.blogspot.com/2026/05/a-panel-of-human-monoclonal-antibodies.html
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Predicting the #antigenic #evolution of seasonal #influenza viruses using phylogenetic #convergence, https://etidiohnew.blogspot.com/2026/04/predicting-antigenic-evolution-of.html
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Predicting the #antigenic #evolution of seasonal #influenza viruses using phylogenetic #convergence, https://etidiohnew.blogspot.com/2026/04/predicting-antigenic-evolution-of.html
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Impact of an #aminoacid #deletion detected in the #hemagglutinin (HA) #antigenic site of swine #influenza A virus field strains on HA antigenicity, https://etidiohnew.blogspot.com/2026/02/impact-of-aminoacid-deletion-detected.html
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Impact of an #aminoacid #deletion detected in the #hemagglutinin (HA) #antigenic site of swine #influenza A virus field strains on HA antigenicity, https://etidiohnew.blogspot.com/2026/02/impact-of-aminoacid-deletion-detected.html
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Functional and #antigenic constraints on the #Nipah virus #fusion protein, https://etidiohnew.blogspot.com/2026/02/functional-and-antigenic-constraints-on.html
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Functional and #antigenic constraints on the #Nipah virus #fusion protein, https://etidiohnew.blogspot.com/2026/02/functional-and-antigenic-constraints-on.html
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Emergence and #antigenic characterisation of #influenza #H3N2 viruses with #hemagglutinin substitutions N158K and K189R during the 2024/25 influenza season, https://etidiohnew.blogspot.com/2026/02/emergence-and-antigenic.html
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Emergence and #antigenic characterisation of #influenza #H3N2 viruses with #hemagglutinin substitutions N158K and K189R during the 2024/25 influenza season, https://etidiohnew.blogspot.com/2026/02/emergence-and-antigenic.html
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#Antigenic #Drift and Antivaccine Shift in the 2025–2026 #Influenza Season, https://etidiohnew.blogspot.com/2026/02/antigenic-drift-and-antivaccine-shift.html
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#Antigenic #Drift and Antivaccine Shift in the 2025–2026 #Influenza Season, https://etidiohnew.blogspot.com/2026/02/antigenic-drift-and-antivaccine-shift.html
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#Molecular basis of 60 years of #antigenic #evolution of #human #influenza #H3N2 virus neuraminidase, https://etidiohnew.blogspot.com/2026/01/molecular-basis-of-60-years-of.html
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#Molecular basis of 60 years of #antigenic #evolution of #human #influenza #H3N2 virus neuraminidase, https://etidiohnew.blogspot.com/2026/01/molecular-basis-of-60-years-of.html
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#Vaccine-induced #antigenic #drift of a #human-origin #H3N2 #Influenza A virus in swine alters glycan binding and sialic acid avidity, https://etidiohnew.blogspot.com/2025/12/vaccine-induced-antigenic-drift-of.html
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#Vaccine-induced #antigenic #drift of a #human-origin #H3N2 #Influenza A virus in swine alters glycan binding and sialic acid avidity, https://etidiohnew.blogspot.com/2025/12/vaccine-induced-antigenic-drift-of.html
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#Antigenic Mapping of #H2 #Influenza Viruses recognized by #Ferret and #Human Sera and Predicting Antigenically Significant Sites, https://etidiohnew.blogspot.com/2025/11/antigenic-mapping-of-h2-influenza.html
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#Antigenic Mapping of #H2 #Influenza Viruses recognized by #Ferret and #Human Sera and Predicting Antigenically Significant Sites, https://etidiohnew.blogspot.com/2025/11/antigenic-mapping-of-h2-influenza.html
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#Genetic and #antigenic characteristics of #zoonotic #influenza A viruses and development of candidate #vaccine viruses for pandemic preparedness (#WHO, Oct. 31 '25), https://etidiohnew.blogspot.com/2025/10/genetic-and-antigenic-characteristics.html
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#Genetic and #antigenic characteristics of #zoonotic #influenza A viruses and development of candidate #vaccine viruses for pandemic preparedness (#WHO, Oct. 31 '25), https://etidiohnew.blogspot.com/2025/10/genetic-and-antigenic-characteristics.html
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Post-infection #pig and #ferret antisera show similar #antigenic profiles for #human #influenza #H1N1pdm09 viruses, https://etidiohnew.blogspot.com/2025/10/post-infection-pig-and-ferret-antisera.html
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Post-infection #pig and #ferret antisera show similar #antigenic profiles for #human #influenza #H1N1pdm09 viruses, https://etidiohnew.blogspot.com/2025/10/post-infection-pig-and-ferret-antisera.html
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H128N Substitution in the Sa #Antigenic Site of HA1 Causes Antigenic Drift Between #Eurasian Avian-like #H1N1 and 2009 #Pandemic H1N1 #Influenza Viruses, https://etidiohnew.blogspot.com/2025/10/h128n-substitution-in-sa-antigenic-site.html
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H128N Substitution in the Sa #Antigenic Site of HA1 Causes Antigenic Drift Between #Eurasian Avian-like #H1N1 and 2009 #Pandemic H1N1 #Influenza Viruses, https://etidiohnew.blogspot.com/2025/10/h128n-substitution-in-sa-antigenic-site.html
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Subtype-specific neutralizing #antibodies promote #antigenic #shift during #influenza virus co-infection, https://etidiohnew.blogspot.com/2025/08/subtype-specific-neutralizing.html
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Subtype-specific neutralizing #antibodies promote #antigenic #shift during #influenza virus co-infection, https://etidiohnew.blogspot.com/2025/08/subtype-specific-neutralizing.html
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Mapping #Haemagglutinin #Residues Driving #Antigenic Diversity in #H5Nx Avian #Influenza Viruses, https://etidiohnew.blogspot.com/2025/06/mapping-haemagglutinin-residues-driving.html
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Mapping #Haemagglutinin #Residues Driving #Antigenic Diversity in #H5Nx Avian #Influenza Viruses, https://etidiohnew.blogspot.com/2025/06/mapping-haemagglutinin-residues-driving.html
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#Antigenic and #virological characteristics of #SARS-CoV-2 #variants BA.3.2, #XFG, and #NB181, https://etidiohnew.blogspot.com/2025/06/antigenic-and-virological.html
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#Antigenic and #virological characteristics of #SARS-CoV-2 #variants BA.3.2, #XFG, and #NB181, https://etidiohnew.blogspot.com/2025/06/antigenic-and-virological.html
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#Genetic and #antigenic characteristics of #zoonotic #influenza A viruses and development of candidate #vaccine viruses for #pandemic preparedness {WHO, March 28 '25}, https://etidiohnew.blogspot.com/2025/03/genetic-and-antigenic-characteristics.html
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#Genetic and #antigenic characteristics of #zoonotic #influenza A viruses and development of candidate #vaccine viruses for #pandemic preparedness {WHO, March 28 '25}, https://etidiohnew.blogspot.com/2025/03/genetic-and-antigenic-characteristics.html
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[Correspondence] #Virological and #antigenic characteristics of #SARS-CoV-2 #variants #LF.7.2.1, #NP.1, and #LP.8.1 https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00015-5/fulltext?rss=yes
... several sublineages of #JN.1 are increasingly out-competing XEC and KP.3.1.1, exhibiting superior growth advantages; for example, LF.7.2.1, MC.10.1, NP.1, and, most importantly, LP.8.1 (figure A, B).
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[Correspondence] #Virological and #antigenic characteristics of #SARS-CoV-2 #variants #LF.7.2.1, #NP.1, and #LP.8.1 https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00015-5/fulltext?rss=yes
... several sublineages of #JN.1 are increasingly out-competing XEC and KP.3.1.1, exhibiting superior growth advantages; for example, LF.7.2.1, MC.10.1, NP.1, and, most importantly, LP.8.1 (figure A, B).
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Virological and #antigenic characteristics of #SARS-CoV-2 #variants #LF721, #NP1, and #LP81, https://etidiohnew.blogspot.com/2024/12/virological-and-antigenic.html
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Virological and #antigenic characteristics of #SARS-CoV-2 #variants #LF721, #NP1, and #LP81, https://etidiohnew.blogspot.com/2024/12/virological-and-antigenic.html
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The #antigenic #landscape of #N1 #neuraminidase in #human #influenza A virus strains isolated between 2009 and 2020, BioRxIV, https://www.biorxiv.org/content/10.1101/2024.12.10.627724v1
The resulting neuraminidase inhibition pattern revealed two antigenic groups that circulated in this period. A machine learning method identified K432E and I321V as key determinants of N1 neuraminidase antigenicity.
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The #antigenic #landscape of #N1 #neuraminidase in #human #influenza A virus strains isolated between 2009 and 2020, BioRxIV, https://www.biorxiv.org/content/10.1101/2024.12.10.627724v1
The resulting neuraminidase inhibition pattern revealed two antigenic groups that circulated in this period. A machine learning method identified K432E and I321V as key determinants of N1 neuraminidase antigenicity.
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Evolving #antibody #response to #SARS-CoV-2 #antigenic #shift from #XBB to #JN1
Source: Nature, AbstractThe continuous evolution of SARS-CoV-2, particularly the emergence of BA.2.86/JN.1 lineage replacing XBB, necessitates re-evaluation of vaccine compositions 1–3. Here, we provide a comprehensive analysis of the humoral immune response to XBB and JN.1 human exposure. We demonstrate the antigenic distinctiveness of XBB and JN.1 lineages in SARS-CoV-2-naive individuals,…
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Evolving #antibody #response to #SARS-CoV-2 #antigenic #shift from #XBB to #JN1
Source: Nature, AbstractThe continuous evolution of SARS-CoV-2, particularly the emergence of BA.2.86/JN.1 lineage replacing XBB, necessitates re-evaluation of vaccine compositions 1–3. Here, we provide a comprehensive analysis of the humoral immune response to XBB and JN.1 human exposure. We demonstrate the antigenic distinctiveness of XBB and JN.1 lineages in SARS-CoV-2-naive individuals,…
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#Human and #hamster #sera correlate well in identifying #antigenic #drift among #SARS-CoV-2 #variants, including #JN1
Source: Journal of Virology, ABSTRACTAntigenic assessments of SARS-CoV-2 variants inform decisions to update COVID-19 vaccines. Primary infection sera are often used for assessments, but such sera are rare due to population immunity from SARS-CoV-2 infections and COVID-19 vaccinations. Here, we show that neutralization titers and breadth of matched…
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#Human and #hamster #sera correlate well in identifying #antigenic #drift among #SARS-CoV-2 #variants, including #JN1
Source: Journal of Virology, ABSTRACTAntigenic assessments of SARS-CoV-2 variants inform decisions to update COVID-19 vaccines. Primary infection sera are often used for assessments, but such sera are rare due to population immunity from SARS-CoV-2 infections and COVID-19 vaccinations. Here, we show that neutralization titers and breadth of matched…
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Triton X-100-treated virus-based ELLA demonstrates discordant #antigenic #evolution of #influenza B virus #hemagglutinin and #neuraminidase
Source: Journal of Viroloyg, ABSTRACTNeuraminidase (NA)-specific antibodies have been associated with protection against influenza and thus NA is considered a promising target for next-generation vaccines against influenza A (IAV) and B viruses (IBV). NA inhibition (NI) by antibodies is typically assessed using an enzyme-linked…
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Triton X-100-treated virus-based ELLA demonstrates discordant #antigenic #evolution of #influenza B virus #hemagglutinin and #neuraminidase
Source: Journal of Viroloyg, ABSTRACTNeuraminidase (NA)-specific antibodies have been associated with protection against influenza and thus NA is considered a promising target for next-generation vaccines against influenza A (IAV) and B viruses (IBV). NA inhibition (NI) by antibodies is typically assessed using an enzyme-linked…
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Structural and immunological characterization of the #H3 #influenza #hemagglutinin during #antigenic #drift, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.09.13.612776v1
In this study, we explore the influence of #glycan #evolution on H3 hemagglutinin from 1968 to present day and its impacts on antigenicity and immunogenicity.
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Structural and immunological characterization of the #H3 #influenza #hemagglutinin during #antigenic #drift, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.09.13.612776v1
In this study, we explore the influence of #glycan #evolution on H3 hemagglutinin from 1968 to present day and its impacts on antigenicity and immunogenicity.
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A broad-spectrum #vaccine #candidate against #H5 viruses bearing different sub-clade 2.3.4.4 #HA genes, npj Vaccines: https://www.nature.com/articles/s41541-024-00947-4
Our analyses identified H5-Re11_Q115L/R120S/A156T (H5-Re11 + 3) as a promising candidate for a broad-spectrum vaccine, positioned centrally in the #antigenic #map, and offering potential universal protection against all variants within the clade 2.3.4.4.
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A broad-spectrum #vaccine #candidate against #H5 viruses bearing different sub-clade 2.3.4.4 #HA genes, npj Vaccines: https://www.nature.com/articles/s41541-024-00947-4
Our analyses identified H5-Re11_Q115L/R120S/A156T (H5-Re11 + 3) as a promising candidate for a broad-spectrum vaccine, positioned centrally in the #antigenic #map, and offering potential universal protection against all variants within the clade 2.3.4.4.
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Rapid #neutralizing #assay for circulating #H5N1 #influenza virus in dairy #cows, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.07.30.605731v1
Our results suggest that the circulating H5N1 virus in cows shares #antigenic characteristics with NIID-002, providing significant implications for the #development and preparation of #vaccines.
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Rapid #neutralizing #assay for circulating #H5N1 #influenza virus in dairy #cows, BioRxIV: https://www.biorxiv.org/content/10.1101/2024.07.30.605731v1
Our results suggest that the circulating H5N1 virus in cows shares #antigenic characteristics with NIID-002, providing significant implications for the #development and preparation of #vaccines.
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#Global #Antigenic #Landscape and #Vaccine Recommendation #Strategy for Low Pathogenic Avian #Influenza A(#H9N2) Viruses, https://www.journalofinfection.com/article/S0163-4453(24)00133-6/fulltext
We develop an antigenicity prediction method for H9N2 viruses. Systematically describe the global antigenic landscape for H9N2 viruses firstly. Identify the determining sites for the complex antigenic transitions in #China. Screen virus strains to improve vaccine strain recommendations.
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#Global #Antigenic #Landscape and #Vaccine Recommendation #Strategy for Low Pathogenic Avian #Influenza A(#H9N2) Viruses, https://www.journalofinfection.com/article/S0163-4453(24)00133-6/fulltext
We develop an antigenicity prediction method for H9N2 viruses. Systematically describe the global antigenic landscape for H9N2 viruses firstly. Identify the determining sites for the complex antigenic transitions in #China. Screen virus strains to improve vaccine strain recommendations.