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#amyotrophiclateralsclerosis — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #amyotrophiclateralsclerosis, aggregated by home.social.

  1. Overactive protein cleanup disrupts nuclear pores in neurodegenerative disease

    When it comes to neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and certain forms of dementia, researchers…
    #Nuclear #amyotrophiclateralsclerosis #Cell #Cytoplasm #Dementia #medicine #Neurodegeneration #NeurodegenerativeDisease #NeurodegenerativeDiseases #Neuron #nuclear #Protein #qualitycontrol #research #RNA #Sclerosis #TDP-43
    europesays.com/2736330/

  2. ALS, the muscle wasting disease of ice bucket challenge fame, is sometimes genetic, sometimes sporadic, but sometimes pops up in clusters. One such cluster in a little skiing village in France unnerved the local GP - and was eventually pinned on false morel mushrooms.

    archive.is/bJMoo

    #AmyotrophicLateralSclerosis #LouGehrigsDisease #MushroomForaging #FalseMorels #Foraging #TheAtlanticMagazine

  3. ALS, the muscle wasting disease of ice bucket challenge fame, is sometimes genetic, sometimes sporadic, but sometimes pops up in clusters. One such cluster in a little skiing village in France unnerved the local GP - and was eventually pinned on false morel mushrooms.

    archive.is/bJMoo

    #AmyotrophicLateralSclerosis #LouGehrigsDisease #MushroomForaging #FalseMorels #Foraging #TheAtlanticMagazine

  4. ALS, the muscle wasting disease of ice bucket challenge fame, is sometimes genetic, sometimes sporadic, but sometimes pops up in clusters. One such cluster in a little skiing village in France unnerved the local GP - and was eventually pinned on false morel mushrooms.

    archive.is/bJMoo

    #AmyotrophicLateralSclerosis #LouGehrigsDisease #MushroomForaging #FalseMorels #Foraging #TheAtlanticMagazine

  5. ALS, the muscle wasting disease of ice bucket challenge fame, is sometimes genetic, sometimes sporadic, but sometimes pops up in clusters. One such cluster in a little skiing village in France unnerved the local GP - and was eventually pinned on false morel mushrooms.

    archive.is/bJMoo

    #AmyotrophicLateralSclerosis #LouGehrigsDisease #MushroomForaging #FalseMorels #Foraging #TheAtlanticMagazine

  6. ALS, the muscle wasting disease of ice bucket challenge fame, is sometimes genetic, sometimes sporadic, but sometimes pops up in clusters. One such cluster in a little skiing village in France unnerved the local GP - and was eventually pinned on false morel mushrooms.

    archive.is/bJMoo

    #AmyotrophicLateralSclerosis #LouGehrigsDisease #MushroomForaging #FalseMorels #Foraging #TheAtlanticMagazine

  7. 60-year-old with recent ALS diagnosis wonders if retirement savings will be enough to cover health care

    Woman receiving distressing news in a letter. Preparing for retirement is a decades-long process we focus on throughout…
    #NewsBeep #News #Personalfinance #amyotrophiclateralsclerosis #Business #CA #Canada #CanadaPensionPlan #CPP #DaveRamsey #Dawn #Finance #PersonalFinance #Retirement #retirementsavings
    newsbeep.com/ca/159775/

  8. Very slick new use for the AVP

    Mark, a 64-year old man with #AmyotrophicLateralSclerosis (#ALS), successfully used his direct thoughts to control the cursor on the #Apple #VisionPro when he played Solitaire, watched #AppleTV and sent text messages using the #Synchron brain computer interface, hands-free. Mark is otherwise unable to use the #AppleVisionPro due to the loss of function of his upper limbs. Apple Vision Pro requires hand gestures to make item selections.

    iclarified.com/94435/apple-vis

  9. The FDA has approved Biogen's ALS drug, Tofersen, an antisense oligo targeting SOD1. I wrote about this back in September in my Clinical Pipeline column as part of a shift towards approving drugs based on biomarkers without clear signs of clinical efficacy*.

    nature.com/articles/d41591-022

    *You can have a look at the trial data in NEJM, in a study that concluded that "In persons with SOD1 ALS, tofersen reduced concentrations of SOD1 in CSF and of neurofilament light chains in plasma over 28 weeks but did not improve clinical end points and was associated with adverse events."

    lnkd.in/dwGMYGgh

    #NatureMedicine #amyotrophiclateralsclerosis #drugdevelopment #pharma

  10. TDP-43 represses cryptic exon splicing in #UNC13A, a risk factor for #AmyotrophicLateralSclerosis (#ALS) & #FrontotemporalDementia (#FTD). While #TDP43 is the main repressor, other hnRNPs may potentially act as disease modifiers @PrudencioLab #PLOSBiology plos.io/3LB8ITH

  11. TDP-43 represses cryptic exon splicing in #UNC13A, a risk factor for #AmyotrophicLateralSclerosis (#ALS) & #FrontotemporalDementia (#FTD). While #TDP43 is the main repressor, other hnRNPs may potentially act as disease modifiers @PrudencioLab #PLOSBiology plos.io/3LB8ITH

  12. TDP-43 represses cryptic exon splicing in #UNC13A, a risk factor for #AmyotrophicLateralSclerosis (#ALS) & #FrontotemporalDementia (#FTD). While #TDP43 is the main repressor, other hnRNPs may potentially act as disease modifiers @PrudencioLab #PLOSBiology plos.io/3LB8ITH

  13. BCI lets completely “locked-in” man communicate with his son, ask for a beer - The Wyss Center for Bio and Neoroengineering has developed communications a... - arstechnica.com/?p=1848415 #amyotrophiclateralsclerosis #brain-computerinterface #neuroscience #science #bci

  14. Brain Implant Allows Fully Paralyzed Patient to Communicate - Letter by painstaking letter, a man in a completely locked-in state was able to formulate... - nytimes.com/2022/03/22/science #naturecommunications(journal) #amyotrophiclateralsclerosis #computersandtheinternet #your-feed-science #your-feed-health #research #alsassn #brain #coma