#alleles — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #alleles, aggregated by home.social.
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Definitions 🧵:
A #haplogroup is a combination of #alleles that tend to be inherited together.
An #allele is a variation of the same sequence of nucleotides at the same place on a DNA molecule.#Haplogroups pertain to a single line of descent. As such, individual membership of a haplogroup relies on a small proportion of the #genetic material possessed by that individual.
Mothers pass on mitochondrial #DNA unmixed to all their children; so the #ancestry can be traced along the maternal line.
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It turns out that a section of our #DNA that we received from Neanderthals is particularly associated with outcomes (mild, severe) of #COVID19 infections.
This paper outlines an approach ranging from population genetics to functional #genomics in which the researchers identified four important #alleles and their likely #regulatory function.
Title: "Regulatory dissection of the severe #COVID-19 risk locus introgressed by #Neanderthals" (Jagoda et al. 2023)