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#adverseeffects — Public Fediverse posts

Live and recent posts from across the Fediverse tagged #adverseeffects, aggregated by home.social.

  1. The claim is circulating that antidepressants can cause overheating and dehydration. This is a genuine public health message, but it's not so simple: diuretics, beta blockers, ACE inhibitors, antipsychotics, and some antihistamines may also interact badly with hot weather.
    nytimes.com/2024/06/15/well/li (excerpt in a reply)

    There's even doubt about antidepressants having this effect. A recent paper in eClinicalMedicine looked at all the studies they could find and concluded that there wasn't evidence of antidepressants causing overheating in hot weather - though some other medicines do.

    "Current evidence supports strong anticholinergics, non-selective beta-blockers, adrenaline, and anti-Parkinson’s agents impairing thermoregulation during heat stress ... physicians should interpret with caution conventional public health messaging related to the thermoregulatory effects of some drugs (e.g., antidepressants) during hot weather."
    thelancet.com/journals/eclinm/

    #Antidepressants #Diuretics #AnticholinergicMedications #MedMastodon #BetaBlockers #HeatWaves #Thermoregulation #OverHeating #Dehydration #SideEffects #AdverseEffects #AdverseEvents #DrugSideEffects #DrugSafety #HeatStress #HotWeather #HotWeatherSafety #PublicHealth #ACEinhibitors #Antipsychotics

  2. pubmed.ncbi.nlm.nih.gov/392308 Adverse Events in Studies of Classic Psychedelics: A Systematic Review and Meta-Analysis (Hinkle, et al, 2024) #psychedelics #adverseeffects #psychedelic — another great opportunity to compare with #ketamine which has similar routes of administration and similar safety data from 60+ years of research and practice. #fda #esketamine #spravato #ketaminetherapy #psychedelictherapy #mdmaassistedpsychotherapy #neuroscience #mdma #mentalhealth #consciousness #plantmedicine

  3. #Evidence Review of the #AdverseEffects of #COVID19 #Vaccination and Intramuscular #Vaccine Administration (2024)

    nap.nationalacademies.org/cata

    👉 The amazing thing is how SAFE these #vaccines are! 👈

    Here is a summary table where I've highlighted the bad things. Note that the only one that is firm is the #mRNA link to #myocarditis in young men (but even this is very rare!). Note that the little 'I's mean insufficient #data.

    Download full #pdf as a guest with your email address.

  4. A clinical trial assessing a synthetic antibody to generate an immediate response and also generate a more durable treatment for solid tumor cancers, advanced to a mid-stage study.

    sciencebusiness.technewslit.co

    #News #Press #Science #Business #Cancer #Biotechnology #ClinicalTrial #Immunotherapy #AdverseEffects #CheckpointInhibitor #Antibody #ImmuneSystem #TCells #InnateImmuneSystem

  5. Trial Underway Testing Dried Plasma for Transfusions

    A clinical trial is recruiting participants to assess the safety and feasibility of a system for spray drying and re-constituting a person's blood plasma.

    sciencebusiness.technewslit.co

    #News #Press #Science #Business #Plasma #Blood #ClinicalTrial #Frozen #SprayDried #MedicalDevice #Trauma #AdverseEffects #ShelfLife #FirstResponders #Military