#adverseeffects — Public Fediverse posts

The claim is circulating that antidepressants can cause overheating and dehydration. This is a genuine public health message, but it's not so simple: diuretics, beta blockers, ACE inhibitors, antipsychotics, and some antihistamines may also interact badly with hot weather.
https://www.nytimes.com/2024/06/15/well/live/heat-weather-medication-safety.html (excerpt in a reply)

There's even doubt about antidepressants having this effect. A recent paper in eClinicalMedicine looked at all the studies they could find and concluded that there wasn't evidence of antidepressants causing overheating in hot weather - though some other medicines do.

"Current evidence supports strong anticholinergics, non-selective beta-blockers, adrenaline, and anti-Parkinson’s agents impairing thermoregulation during heat stress ... physicians should interpret with caution conventional public health messaging related to the thermoregulatory effects of some drugs (e.g., antidepressants) during hot weather."
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00465-6/fulltext

#Antidepressants #Diuretics #AnticholinergicMedications #MedMastodon #BetaBlockers #HeatWaves #Thermoregulation #OverHeating #Dehydration #SideEffects #AdverseEffects #AdverseEvents #DrugSideEffects #DrugSafety #HeatStress #HotWeather #HotWeatherSafety #PublicHealth #ACEinhibitors #Antipsychotics

The claim is circulating that antidepressants can cause overheating and dehydration. This is a genuine public health message, but it's not so simple: diuretics, beta blockers, ACE inhibitors, antipsychotics, and some antihistamines may also interact badly with hot weather.
https://www.nytimes.com/2024/06/15/well/live/heat-weather-medication-safety.html (excerpt in a reply)

There's even doubt about antidepressants having this effect. A recent paper in eClinicalMedicine looked at all the studies they could find and concluded that there wasn't evidence of antidepressants causing overheating in hot weather - though some other medicines do.

"Current evidence supports strong anticholinergics, non-selective beta-blockers, adrenaline, and anti-Parkinson’s agents impairing thermoregulation during heat stress ... physicians should interpret with caution conventional public health messaging related to the thermoregulatory effects of some drugs (e.g., antidepressants) during hot weather."
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00465-6/fulltext

#Antidepressants #Diuretics #AnticholinergicMedications #MedMastodon #BetaBlockers #HeatWaves #Thermoregulation #OverHeating #Dehydration #SideEffects #AdverseEffects #AdverseEvents #DrugSideEffects #DrugSafety #HeatStress #HotWeather #HotWeatherSafety #PublicHealth #ACEinhibitors #Antipsychotics

https://pubmed.ncbi.nlm.nih.gov/39230883/ Adverse Events in Studies of Classic Psychedelics: A Systematic Review and Meta-Analysis (Hinkle, et al, 2024) #psychedelics #adverseeffects #psychedelic — another great opportunity to compare with #ketamine which has similar routes of administration and similar safety data from 60+ years of research and practice. #fda #esketamine #spravato #ketaminetherapy #psychedelictherapy #mdmaassistedpsychotherapy #neuroscience #mdma #mentalhealth #consciousness #plantmedicine

#Evidence Review of the #AdverseEffects of #COVID19 #Vaccination and Intramuscular #Vaccine Administration (2024)

https://nap.nationalacademies.org/catalog/27746/evidence-review-of-the-adverse-effects-of-covid-19-vaccination-and-intramuscular-vaccine-administration

👉 The amazing thing is how SAFE these #vaccines are! 👈

Here is a summary table where I've highlighted the bad things. Note that the only one that is firm is the #mRNA link to #myocarditis in young men (but even this is very rare!). Note that the little 'I's mean insufficient #data.

Download full #pdf as a guest with your email address.

#Evidence Review of the #AdverseEffects of #COVID19 #Vaccination and Intramuscular #Vaccine Administration (2024)

https://nap.nationalacademies.org/catalog/27746/evidence-review-of-the-adverse-effects-of-covid-19-vaccination-and-intramuscular-vaccine-administration

👉 The amazing thing is how SAFE these #vaccines are! 👈

Here is a summary table where I've highlighted the bad things. Note that the only one that is firm is the #mRNA link to #myocarditis in young men (but even this is very rare!). Note that the little 'I's mean insufficient #data.

Download full #pdf as a guest with your email address.

Therapeutic Psilocybin's Adverse Effects Mostly Resolved Within 2 Days (Harris, 2024)
https://jamanetwork.com/journals/jama/fullarticle/2818439 #psilocybin #psychedelicresearch #psychedelics #plantmedicine #psychedelictherapy #adverseeffects

Initial findings from a large clinical trial testing a vaccine against the chikungunya virus show the vaccine generates protective antibodies in the vast majority of recipients.

https://sciencebusiness.technewslit.com/?p=45079

#News #Press #Science #Business #Biotechnology #Chikungunya #Virus #Mosquitoes #Fever #ClinicalTrial #Antibodies #Placebo #AdverseEffects #Efficacy #Denmark

Initial findings from a large clinical trial testing a vaccine against the chikungunya virus show the vaccine generates protective antibodies in the vast majority of recipients.

https://sciencebusiness.technewslit.com/?p=45079

#News #Press #Science #Business #Biotechnology #Chikungunya #Virus #Mosquitoes #Fever #ClinicalTrial #Antibodies #Placebo #AdverseEffects #Efficacy #Denmark

A clinical trial assessing a synthetic antibody to generate an immediate response and also generate a more durable treatment for solid tumor cancers, advanced to a mid-stage study.

https://sciencebusiness.technewslit.com/?p=45068

#News #Press #Science #Business #Cancer #Biotechnology #ClinicalTrial #Immunotherapy #AdverseEffects #CheckpointInhibitor #Antibody #ImmuneSystem #TCells #InnateImmuneSystem

A clinical trial assessing a synthetic antibody to generate an immediate response and also generate a more durable treatment for solid tumor cancers, advanced to a mid-stage study.

https://sciencebusiness.technewslit.com/?p=45068

#News #Press #Science #Business #Cancer #Biotechnology #ClinicalTrial #Immunotherapy #AdverseEffects #CheckpointInhibitor #Antibody #ImmuneSystem #TCells #InnateImmuneSystem

If you were asked for 4 of your publications that were
- something old
- sth new
- sth borrowed
- sth blue
which would it be?

### ###

Old:
https://www.tandfonline.com/doi/full/10.1080/10503307.2010.549520
#RCT #PsychotherapyResearch

New:
https://www.cambridge.org/core/journals/bjpsych-open/article/prevalence-of-physical-health-conditions-and-health-risk-behaviours-in-people-with-severe-mental-illness-in-south-asia-multicountry-crosssectional-survey/793439A315E2AF13A2FA5CC33042B7BB
#GlobalMentalHealth

Borrowed (educational piece for practice audience):
https://onlinelibrary.wiley.com/doi/full/10.1002/cpp.2742
#ClinicalPsychology #Psychometrics

Blue:
https://www.tandfonline.com/doi/full/10.1080/10503307.2022.2095237
#NegativeEffects #AdverseEffects #UnderResearched

#AcademicChatter

Trial Underway Testing Dried Plasma for Transfusions

A clinical trial is recruiting participants to assess the safety and feasibility of a system for spray drying and re-constituting a person's blood plasma.

https://sciencebusiness.technewslit.com/?p=44985

#News #Press #Science #Business #Plasma #Blood #ClinicalTrial #Frozen #SprayDried #MedicalDevice #Trauma #AdverseEffects #ShelfLife #FirstResponders #Military

Trial Underway Testing Dried Plasma for Transfusions

A clinical trial is recruiting participants to assess the safety and feasibility of a system for spray drying and re-constituting a person's blood plasma.

https://sciencebusiness.technewslit.com/?p=44985

#News #Press #Science #Business #Plasma #Blood #ClinicalTrial #Frozen #SprayDried #MedicalDevice #Trauma #AdverseEffects #ShelfLife #FirstResponders #Military

Nasal Spray Reduces Flu Duration in Challenge Trial

An #influenza #vaccine given as a nasal spray is shown in a clinical trial to reduce the amount of time participants have #flu #infections, when exposed to the #virus.

https://sciencebusiness.technewslit.com/?p=44446

#News #Science #Business #Biotechnology #ClinicalTrial #ChallengeTrial #NasalSpray #AdverseEffects #ImmuneSystem #Australia #UK

Nasal Spray Reduces Flu Duration in Challenge Trial

An #influenza #vaccine given as a nasal spray is shown in a clinical trial to reduce the amount of time participants have #flu #infections, when exposed to the #virus.

https://sciencebusiness.technewslit.com/?p=44446

#News #Science #Business #Biotechnology #ClinicalTrial #ChallengeTrial #NasalSpray #AdverseEffects #ImmuneSystem #Australia #UK

Le CDC: 118 000 kids and young adukts died from #adverseEffects of #mrna #vaccines in the US.
#dropDead https://expose-news.com/2022/11/30/usa-118k-children-died-suddenly-covid-vaccine/