#3rs — Public Fediverse posts

🐾 Toxicity testing in #DrugDevelopment typically involves two species of animal.
💡 But what if we could reduce the number of species used to one?
That's the thinking behind a topic in IHI call 13 - we're looking for a consortium to develop a weight-of-evidence for a standardised process to waive the second species and build an AI-driven model to select the most appropriate single species to be used.
📅 Deadline: 8 October
👉 https://link.europa.eu/tTtV7C
#IHITransformingHealth #HorizonEU #3Rs #research

📢 Apply now to help reduce animal use in #DrugSafety studies! IHI's call 13 topic 2 is searching for projects to produce:
🤖 An AI-driven model to identify the most appropriate single species
🐾 A framework to support waiving the 2nd species.
⏰ 8 Oct
👉 https://www.ihi.europa.eu/ihi-call-13
#HorizonEU #3Rs

👋 Meet Aurora Signorazzi - passionate about alternatives to animal testing 🐾
She carried out her PhD in #3Rs in #vaccines as part of VAC2VAC & went on to have a successful career in the pharma industry & medical regulation.
👉 https://link.europa.eu/9DrdtQ
#ResearchCareers #HealthResearch #RegulatoryScience #EU #Health #Innovation

💡 Creating synergies between projects can help to reduce duplication of efforts & increase efficiencies in #HealthResearch.
🙏 Bigpicture & VICT3R are great examples of how collaboration can amplify the impact of a public-private partnership.
👉 Read more: https://link.europa.eu/N7tBKC
#IHITransformingHealth #HorizonEU #Pathology #3Rs #Health #Research #Collaboration

📢 Read all about it! IHI's newsletter is now online!
👉 https://link.europa.eu/Y7tymh
Discover: draft topic texts for call 13, #3Rs, #PROMs & PREMs in heart patients, #LiverScreening, the @afbstep.bsky.social project, #EarlyCareerResearchers & much more!
👉 https://link.europa.eu/Y7tymh #Health #Research #EU #WeekendReading #IHITransformingHealth #HorizonEU

🐾 Today is the #WorldDayForLaboratoryAnimals! Find out about our projects working on the #3Rs.
🐭 VICT3R developed virtual control groups that could replace 4000 rats in preclinical studies in the EU every year
🐠 PREMIER developed a decision tree that could reduce the number of fish used in environmental risk assessments for older medicines by 30%
🧫 EBiSC is a bank of induced pluripotent stem cells which can be used instead of animals in many studies
👉 https://link.europa.eu/vqtDFQ
#Animals #Research

IHI project VICT3R has reached an important milestone in its quest to dramatically reduce the numbers of animals used in medicine safety testing by replacing actual control groups with ‘Virtual Control Groups’ (VCGs).
The European Medicines Agency has launched a consultation on a qualification opinion on the use of VCGs, as proposed by VICT3R, in certain studies. The consultation will run until 12 May, and details can be found at https://link.europa.eu/XqwHjG.

#HorizonEU #3Rs #health #research

80,000 € for animal welfare in #research: The DFG announces the Ursula M. Händel Prize for the 11th time. It aims to honour outstanding contributions to promoting animal welfare in science and committments to the use of the #3Rs concept. More: https://fcld.ly/animalwelfare

🐾 On #WorldAnimalDay, find out how new IHI project VICT3R plans to dramatically cut the use of animals in research - they will use existing data and #ArtificialIntelligence to create virtual control groups that could replace real animals in drug and chemical safety studies.
👉 https://europa.eu/!WPWDR6
#IHITransformingHealth #HorizonEU #3Rs #health #research

📰 Our September newsletter is out now at https://europa.eu/!6HxqxF
📢 News on our next call for proposals
✅ The newly-published evaluation of IMI2 and IHI
🐾 IMI project VAC2VAC's role in a 'historic' #3Rs decision to drop a common animal test
💔 BigData@Heart found that fitness trackers can provide useful info for people with #HeartDisease
👩‍🔬 How public-private partnerships are key to the fight against #AntimicrobialResistance
👋 We meet new project IHI-SYNTHIA
#IHITransformingHealth #HorizonEU

🐇 A 'historic' decision to drop a common animal test for contaminants in batches of medicines administered by injection was driven in part thanks to evidence from IMI project VAC2VAC, which demonstrated that non-animal alternatives are up to the job!
👉 https://europa.eu/!NG4XBk
#3Rs #IHITransformingHealth #HorizonEU

Finnish #3Rs center https://fin3r.fi/en is continuing with the webinars - on Jan 15th at 1 pm CET, Dr. Esther Pearl from https://www.nc3rs.org.uk/ will talk about Robust experimental design with the Experimental Design Assistant (EDA). Register for the webinar at https://helsinki.zoom.us/meeting/register/u5Eld-GspjIiEtahaijnK9tmofWAZaPCgttC

RT @CCAAM_CaCVAM: Incredibly inspiring week at #ECVAM JRC Summer School on Non-Animal Approaches in Science! Young scientists from 31 countries already thinking outside the cage give so much hope for advancing #alternatives and the #3Rs for a future without animal testing! #Science #innovation https://t.co/MqyFhnbH2u

🐦🔗: https://n.respublicae.eu/EU_ScienceHub/status/1662714648745967618

🗓️ Save the date!

EMA is committed to replace, reduce, refine (#3Rs) #animaltesting in the development of human & veterinary medicines.

Interested in #AnimalWelfare? Join us online on 28 Feb, 9:00 - 9:45, to learn more on the Agency's work in this field & share your views.

🐦🔗: https://n.respublicae.eu/EMA_News/status/1627972847745245186

Animal Welfare Information Center (AWIC) at USDA is hiring a #librarian - looking for a recent graduate to support literature searching and evidence-based reviews on veterinary science, animal welfare, biomedical research https://www.usajobs.gov/job/700154300 #3Rs #AnimalWelfare #libraryjobs

My #introduction - researcher at the University of Helsinki, Finland interested in improving #preclinical research: #reproducibility and #3Rs via networking with other scientists in the field: https://www.cost.eu/actions/CA20135/
https://www.cost.eu/actions/CA21139/
https://fin3r.fi/en
https://www.finnish-rn.org/
https://quality-preclinical-data.eu/

Rethink #farm #animal #production: the #3Rs [#Replacement, #Reduction, #Refinement]

"70 billion terrestrial animals and between 59 and 129 billion aquatic animals are used annually, compared with 192 million #research animals [~670 times less animals]. However, animal #farming is not scrutinized through the lens of the 3Rs and instead remains focused on increasing production to feed the world. The justification for this #ethical discrepancy is unclear."

https://www.science.org/doi/10.1126/science.adf3351

RT @[email protected]

📢We are very excited to announce Marcelle Holloway from the #EURL #ECVAM as #keynote speaker at the #3R #Conference on May 12+13 in Tübingen! She is an expert on #AlternativesToAnimalTesting and the #3Rs in #science, #education & #training. Registration: http://bit.ly/3u97jcO

🐦🔗: https://twitter.com/3RCenter/status/1518568614605041664