#pangraph — Public Fediverse posts
Live and recent posts from across the Fediverse tagged #pangraph, aggregated by home.social.
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@foaylward
Github: https://github.com/downingtim/Panalyze/#PanGraph could be another #pangenome graph option if you find pggb to be too compute intensive. PanGraph uses a progressive MSA strategy based upon a guide tree so it scales ~linearly to the # of input genomes (unlike pggb-based programs that are quadratic w.r.t. the # input genomes due to its all-vs-all pairwise alignments). PanGraph should be faster but sacrifices some global optimality due to its guide tree use.