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#methyltransferases — Public Fediverse posts

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  1. The structure of the RNA-recognition motif of fruit fly TRMT2A is highly similar to that of the human enzyme despite low sequence similarity @ActaCrystF
    #RRM #TRMT2A #Methyltransferases doi.org/10.1107/S2053230X24000

  2. We can now enzymatically generate S-adenosyl-L-methionine (SAM) analogues with modifications at the sulfonium center AND at the nucleoside. These can be used to increase the selectivity of certain #methyltransferases over others. Big thanks to Mehmet, Aileen, Ezgi and Andrea!