#estimands — Public Fediverse posts

I think this is a next/ remaining frontier for pragmatic #RCTs in this area and the concept of #Estimands could potentially help here, as an approach to link several elements for trial and intervention planning
https://jpro.springeropen.com/articles/10.1186/s41687-020-00218-5

While the intervention should not be planned to fit a trial, it is clearly possible to develop an intervention with an outcome in mind and theorise about the direction and size/relevance of expected effects.