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70 results for “nlmixr2”

  1. Matthew L Fidler @mattfidler ·

    One of the things I often get asked is if you can use in submissions. We were invited to meet with some of the FDA reviewers, and they confirmed they have received submissions in nlmixr2 and no issues were raised about its use

    blog.nlmixr2.org/blog/2026-04-

    #nlmixr2
  2. Matthew L Fidler @[email protected] ·

    One of the things I often get asked is if you can use #nlmixr2 in submissions. We were invited to meet with some of the FDA reviewers, and they confirmed they have received submissions in nlmixr2 and no issues were raised about its use

    blog.nlmixr2.org/blog/2026-04-

    #nlmixr2
  3. Matthew L Fidler @mattfidler ·

    We are excited to announce a new feature in nlmixr2: mceta for FOCEi. This is a hybrid approach combines Monte-Carlo sampling with the classical FOCEi algorithm bringing flexibility & robustness to nonlinear mixed-effects modeling in pharmacometrics.

    #nlmixr2 #rstats
  4. Matthew L Fidler @[email protected] ·

    We are excited to announce a new feature in nlmixr2: mceta for FOCEi. This is a hybrid approach combines Monte-Carlo sampling with the classical FOCEi algorithm bringing flexibility & robustness to nonlinear mixed-effects modeling in pharmacometrics. #nlmixr2 #rstats

    #nlmixr2 #rstats
  5. Matthew L Fidler @[email protected] ·

    We are excited to announce a new feature in nlmixr2: mceta for FOCEi. This is a hybrid approach combines Monte-Carlo sampling with the classical FOCEi algorithm bringing flexibility & robustness to nonlinear mixed-effects modeling in pharmacometrics. #nlmixr2 #rstats

    #nlmixr2 #rstats
  6. Matthew L Fidler @[email protected] ·

    We are excited to announce a new feature in nlmixr2: mceta for FOCEi. This is a hybrid approach combines Monte-Carlo sampling with the classical FOCEi algorithm bringing flexibility & robustness to nonlinear mixed-effects modeling in pharmacometrics. #nlmixr2 #rstats

    #nlmixr2 #rstats
  7. Matthew L Fidler @mattfidler ·

    New features in 4.0, a package include a vere-style loading, importing models from older versions of nlmixr2 and Rstudio bug fixes. See blog.nlmixr2.org/blog/2025-08-

    #nlmixr2 #rstats
  8. Matthew L Fidler @[email protected] ·

    New features in #nlmixr2 4.0, a #rstats package include a vere-style loading, importing models from older versions of nlmixr2 and Rstudio bug fixes. See blog.nlmixr2.org/blog/2025-08-

    #nlmixr2 #rstats
  9. Matthew L Fidler @[email protected] ·

    New features in #nlmixr2 4.0, a #rstats package include a vere-style loading, importing models from older versions of nlmixr2 and Rstudio bug fixes. See blog.nlmixr2.org/blog/2025-08-

    #nlmixr2 #rstats
  10. Matthew L Fidler @[email protected] ·

    New features in #nlmixr2 4.0, a #rstats package include a vere-style loading, importing models from older versions of nlmixr2 and Rstudio bug fixes. See blog.nlmixr2.org/blog/2025-08-

    #nlmixr2 #rstats
  11. Matthew L Fidler @mattfidler ·

    In this month's Blog, I discuss a new feature in the nlmixr2 ecosystem (in babelmixr2) -- translating and using nlmixr2 models in optimal design. They are fast and easy to use making this my go to tool when doing optimal design.

    blog.nlmixr2.org/blog/2024-11-

    #nlmixr2 #rstats
  12. Matthew L Fidler @[email protected] ·

    In this month's Blog, I discuss a new feature in the nlmixr2 ecosystem (in babelmixr2) -- translating and using nlmixr2 models in optimal design. They are fast and easy to use making this my go to tool when doing optimal design. #nlmixr2 #rstats

    blog.nlmixr2.org/blog/2024-11-

    #nlmixr2 #rstats
  13. Matthew L Fidler @[email protected] ·

    In this month's Blog, I discuss a new feature in the nlmixr2 ecosystem (in babelmixr2) -- translating and using nlmixr2 models in optimal design. They are fast and easy to use making this my go to tool when doing optimal design. #nlmixr2 #rstats

    blog.nlmixr2.org/blog/2024-11-

    #nlmixr2 #rstats
  14. Matthew L Fidler @[email protected] ·

    In this month's Blog, I discuss a new feature in the nlmixr2 ecosystem (in babelmixr2) -- translating and using nlmixr2 models in optimal design. They are fast and easy to use making this my go to tool when doing optimal design. #nlmixr2 #rstats

    blog.nlmixr2.org/blog/2024-11-

    #nlmixr2 #rstats
  15. Matthew L Fidler @mattfidler ·

    nlmixr2 and rxode2 3.0 is out. It is a major release since there are some backward-incompatible changes.

    blog.nlmixr2.org/blog/2024-09-

    #nlmixr2 #rxode2 #rstats
  16. Matthew L Fidler @[email protected] ·

    nlmixr2 and rxode2 3.0 is out. It is a major release since there are some backward-incompatible changes. #nlmixr2 #rxode2 #rstats

    blog.nlmixr2.org/blog/2024-09-

    #nlmixr2 #rxode2 #rstats
  17. Matthew L Fidler @[email protected] ·

    nlmixr2 and rxode2 3.0 is out. It is a major release since there are some backward-incompatible changes. #nlmixr2 #rxode2 #rstats

    blog.nlmixr2.org/blog/2024-09-

    #nlmixr2 #rxode2 #rstats
  18. Matthew L Fidler @[email protected] ·

    nlmixr2 and rxode2 3.0 is out. It is a major release since there are some backward-incompatible changes. #nlmixr2 #rxode2 #rstats

    blog.nlmixr2.org/blog/2024-09-

    #rstats #rxode2 #nlmixr2
  19. Matthew L Fidler @mattfidler ·

    We have a new nlmixr2 blog entry courtesy of Hitesh Mistry and Nicola Melillo (@NicolaMelillo) detailing how to upscale nlmixr2 using AWS. This is helpful for long running SAEM models. In the future it may be even more interesting with other methods parallelized. ( )

    blog.nlmixr2.org/blog/2024-03-

    #nlmixr2 #rstats
  20. Matthew L Fidler @[email protected] ·

    We have a new nlmixr2 blog entry courtesy of Hitesh Mistry and Nicola Melillo (@NicolaMelillo) detailing how to upscale nlmixr2 using AWS. This is helpful for long running SAEM models. In the future it may be even more interesting with other methods parallelized. (#nlmixr2 #rstats)

    blog.nlmixr2.org/blog/2024-03-

    #nlmixr2 #rstats
  21. Matthew L Fidler @[email protected] ·

    We have a new nlmixr2 blog entry courtesy of Hitesh Mistry and Nicola Melillo (@NicolaMelillo) detailing how to upscale nlmixr2 using AWS. This is helpful for long running SAEM models. In the future it may be even more interesting with other methods parallelized. (#nlmixr2 #rstats)

    blog.nlmixr2.org/blog/2024-03-

    #nlmixr2 #rstats
  22. Matthew L Fidler @[email protected] ·

    We have a new nlmixr2 blog entry courtesy of Hitesh Mistry and Nicola Melillo (@NicolaMelillo) detailing how to upscale nlmixr2 using AWS. This is helpful for long running SAEM models. In the future it may be even more interesting with other methods parallelized. (#nlmixr2 #rstats)

    blog.nlmixr2.org/blog/2024-03-

    #nlmixr2 #rstats
  23. Matthew L Fidler @mattfidler ·

    A new version of was released on CRAN today. I will talk about a few features in the future:

    - More flexible mu referencing

    - User defined functions can now be used with nlmixr2 and rxode2

    - Event handling changes

    - Many new estimation methods for population only fitting
    I am very grateful for both the nlmixr2 team and the nlmixr2 users who have helped me get to this point in nlmixr2's development.

    See the blog for more details about the release.

    blog.nlmixr2.org/blog/2024-01-

    #nlmixr2
  24. Matthew L Fidler @[email protected] ·

    A new version of #nlmixr2 was released on CRAN today. I will talk about a few features in the future:

    - More flexible mu referencing

    - User defined functions can now be used with nlmixr2 and rxode2

    - Event handling changes

    - Many new estimation methods for population only fitting
    I am very grateful for both the nlmixr2 team and the nlmixr2 users who have helped me get to this point in nlmixr2's development.

    See the blog for more details about the release.

    blog.nlmixr2.org/blog/2024-01-

    #nlmixr2
  25. Matthew L Fidler @[email protected] ·

    A new version of #nlmixr2 was released on CRAN today. I will talk about a few features in the future:

    - More flexible mu referencing

    - User defined functions can now be used with nlmixr2 and rxode2

    - Event handling changes

    - Many new estimation methods for population only fitting
    I am very grateful for both the nlmixr2 team and the nlmixr2 users who have helped me get to this point in nlmixr2's development.

    See the blog for more details about the release.

    blog.nlmixr2.org/blog/2024-01-

    #nlmixr2
  26. Matthew L Fidler @[email protected] ·

    A new version of #nlmixr2 was released on CRAN today. I will talk about a few features in the future:

    - More flexible mu referencing

    - User defined functions can now be used with nlmixr2 and rxode2

    - Event handling changes

    - Many new estimation methods for population only fitting
    I am very grateful for both the nlmixr2 team and the nlmixr2 users who have helped me get to this point in nlmixr2's development.

    See the blog for more details about the release.

    blog.nlmixr2.org/blog/2024-01-

    #nlmixr2
  27. Matthew L Fidler @[email protected] ·

    A new version of #nlmixr2 was released on CRAN today. I will talk about a few features in the future:

    - More flexible mu referencing

    - User defined functions can now be used with nlmixr2 and rxode2

    - Event handling changes

    - Many new estimation methods for population only fitting
    I am very grateful for both the nlmixr2 team and the nlmixr2 users who have helped me get to this point in nlmixr2's development.

    See the blog for more details about the release.

    blog.nlmixr2.org/blog/2024-01-

    #nlmixr2
  28. nlmixr2 @nlmixr2 ·

    Our colleagues at LAP&P are hosting a target-mediated drug disposition course using at in A Coruña, Spain!

    This is your chance to see nlmixr2 put through its paces in real-world by a world-class consulting team.

    lapp.nl/lapp-page-course/

    #tmdd #nlmixr2 #page2023 #pharmacometrics
  29. nlmixr2 @[email protected] ·

    Our colleagues at LAP&P are hosting a target-mediated drug disposition #TMDD course using #nlmixr2 at #PAGE2023 in A Coruña, Spain!

    This is your chance to see nlmixr2 put through its paces in real-world #pharmacometrics by a world-class consulting team.

    lapp.nl/lapp-page-course/

    #tmdd #nlmixr2 #page2023 #pharmacometrics
  30. John Harrold @[email protected] ·

    @justinwilkins @damiacer

    That's what I was thinking. I think #nlmixr2 would fit right in there. Do you know folks at Roche? We should approach them.

    #nlmixr2
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