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187 results for “mattfidler”

  1. Francois MERCIER @[email protected] ·

    @justinwilkins @timwaterhouse @Tensfeldt @AbuMirchi @DerriereLaLune @callisto @MikeKSmith @dcnorris @Sjtpharm @chrisrackauckas @mattfidler @FlyingGardener @rfaelens

    Welcome @jameslu on #pharmacometrics!

    #pharmacometrics
  2. Francois MERCIER @[email protected] ·

    @justinwilkins @FlyingGardener @MikeKSmith @Tensfeldt @AbuMirchi @chrisrackauckas @dcnorris @DerriereLaLune @timwaterhouse @callisto @Sjtpharm @mattfidler
    ... inviting @IDPharmacometrx to the #pharmacometrics crew here

    #pharmacometrics
  3. Matthew L Fidler @mattfidler ·

    One of the things I often get asked is if you can use in submissions. We were invited to meet with some of the FDA reviewers, and they confirmed they have received submissions in nlmixr2 and no issues were raised about its use

    blog.nlmixr2.org/blog/2026-04-

    #nlmixr2
  4. Matthew L Fidler @[email protected] ·

    One of the things I often get asked is if you can use #nlmixr2 in submissions. We were invited to meet with some of the FDA reviewers, and they confirmed they have received submissions in nlmixr2 and no issues were raised about its use

    blog.nlmixr2.org/blog/2026-04-

    #nlmixr2
  5. Matthew L Fidler @mattfidler ·

    We are excited to announce a new feature in nlmixr2: mceta for FOCEi. This is a hybrid approach combines Monte-Carlo sampling with the classical FOCEi algorithm bringing flexibility & robustness to nonlinear mixed-effects modeling in pharmacometrics.

    #nlmixr2 #rstats
  6. Matthew L Fidler @[email protected] ·

    We are excited to announce a new feature in nlmixr2: mceta for FOCEi. This is a hybrid approach combines Monte-Carlo sampling with the classical FOCEi algorithm bringing flexibility & robustness to nonlinear mixed-effects modeling in pharmacometrics. #nlmixr2 #rstats

    #nlmixr2 #rstats
  7. Matthew L Fidler @[email protected] ·

    We are excited to announce a new feature in nlmixr2: mceta for FOCEi. This is a hybrid approach combines Monte-Carlo sampling with the classical FOCEi algorithm bringing flexibility & robustness to nonlinear mixed-effects modeling in pharmacometrics. #nlmixr2 #rstats

    #nlmixr2 #rstats
  8. Matthew L Fidler @[email protected] ·

    We are excited to announce a new feature in nlmixr2: mceta for FOCEi. This is a hybrid approach combines Monte-Carlo sampling with the classical FOCEi algorithm bringing flexibility & robustness to nonlinear mixed-effects modeling in pharmacometrics. #nlmixr2 #rstats

    #rstats #nlmixr2
  9. Matthew L Fidler @[email protected] ·

    We are excited to announce a new feature in nlmixr2: mceta for FOCEi. This is a hybrid approach combines Monte-Carlo sampling with the classical FOCEi algorithm bringing flexibility & robustness to nonlinear mixed-effects modeling in pharmacometrics. #nlmixr2 #rstats

    #nlmixr2 #rstats
  10. Matthew L Fidler @mattfidler ·

    New features in 4.0, a package include a vere-style loading, importing models from older versions of nlmixr2 and Rstudio bug fixes. See blog.nlmixr2.org/blog/2025-08-

    #nlmixr2 #rstats
  11. Matthew L Fidler @[email protected] ·

    New features in #nlmixr2 4.0, a #rstats package include a vere-style loading, importing models from older versions of nlmixr2 and Rstudio bug fixes. See blog.nlmixr2.org/blog/2025-08-

    #nlmixr2 #rstats
  12. Matthew L Fidler @[email protected] ·

    New features in #nlmixr2 4.0, a #rstats package include a vere-style loading, importing models from older versions of nlmixr2 and Rstudio bug fixes. See blog.nlmixr2.org/blog/2025-08-

    #nlmixr2 #rstats
  13. Matthew L Fidler @[email protected] ·

    New features in #nlmixr2 4.0, a #rstats package include a vere-style loading, importing models from older versions of nlmixr2 and Rstudio bug fixes. See blog.nlmixr2.org/blog/2025-08-

    #rstats #nlmixr2
  14. Matthew L Fidler @[email protected] ·

    New features in #nlmixr2 4.0, a #rstats package include a vere-style loading, importing models from older versions of nlmixr2 and Rstudio bug fixes. See blog.nlmixr2.org/blog/2025-08-

    #nlmixr2 #rstats
  15. Matthew L Fidler @mattfidler ·

    In this month's Blog, I discuss a new feature in the nlmixr2 ecosystem (in babelmixr2) -- translating and using nlmixr2 models in optimal design. They are fast and easy to use making this my go to tool when doing optimal design.

    blog.nlmixr2.org/blog/2024-11-

    #nlmixr2 #rstats
  16. Matthew L Fidler @[email protected] ·

    In this month's Blog, I discuss a new feature in the nlmixr2 ecosystem (in babelmixr2) -- translating and using nlmixr2 models in optimal design. They are fast and easy to use making this my go to tool when doing optimal design. #nlmixr2 #rstats

    blog.nlmixr2.org/blog/2024-11-

    #nlmixr2 #rstats
  17. Matthew L Fidler @[email protected] ·

    In this month's Blog, I discuss a new feature in the nlmixr2 ecosystem (in babelmixr2) -- translating and using nlmixr2 models in optimal design. They are fast and easy to use making this my go to tool when doing optimal design. #nlmixr2 #rstats

    blog.nlmixr2.org/blog/2024-11-

    #nlmixr2 #rstats
  18. Matthew L Fidler @[email protected] ·

    In this month's Blog, I discuss a new feature in the nlmixr2 ecosystem (in babelmixr2) -- translating and using nlmixr2 models in optimal design. They are fast and easy to use making this my go to tool when doing optimal design. #nlmixr2 #rstats

    blog.nlmixr2.org/blog/2024-11-

    #rstats #nlmixr2
  19. Matthew L Fidler @[email protected] ·

    In this month's Blog, I discuss a new feature in the nlmixr2 ecosystem (in babelmixr2) -- translating and using nlmixr2 models in optimal design. They are fast and easy to use making this my go to tool when doing optimal design. #nlmixr2 #rstats

    blog.nlmixr2.org/blog/2024-11-

    #nlmixr2 #rstats
  20. Matthew L Fidler @mattfidler ·

    nlmixr2 and rxode2 3.0 is out. It is a major release since there are some backward-incompatible changes.

    blog.nlmixr2.org/blog/2024-09-

    #nlmixr2 #rxode2 #rstats
  21. Matthew L Fidler @[email protected] ·

    nlmixr2 and rxode2 3.0 is out. It is a major release since there are some backward-incompatible changes. #nlmixr2 #rxode2 #rstats

    blog.nlmixr2.org/blog/2024-09-

    #nlmixr2 #rxode2 #rstats
  22. Matthew L Fidler @[email protected] ·

    nlmixr2 and rxode2 3.0 is out. It is a major release since there are some backward-incompatible changes. #nlmixr2 #rxode2 #rstats

    blog.nlmixr2.org/blog/2024-09-

    #nlmixr2 #rxode2 #rstats
  23. Matthew L Fidler @[email protected] ·

    nlmixr2 and rxode2 3.0 is out. It is a major release since there are some backward-incompatible changes. #nlmixr2 #rxode2 #rstats

    blog.nlmixr2.org/blog/2024-09-

    #rstats #rxode2 #nlmixr2
  24. Matthew L Fidler @mattfidler ·

    We have a new nlmixr2 blog entry courtesy of Hitesh Mistry and Nicola Melillo (@NicolaMelillo) detailing how to upscale nlmixr2 using AWS. This is helpful for long running SAEM models. In the future it may be even more interesting with other methods parallelized. ( )

    blog.nlmixr2.org/blog/2024-03-

    #nlmixr2 #rstats
  25. Matthew L Fidler @[email protected] ·

    We have a new nlmixr2 blog entry courtesy of Hitesh Mistry and Nicola Melillo (@NicolaMelillo) detailing how to upscale nlmixr2 using AWS. This is helpful for long running SAEM models. In the future it may be even more interesting with other methods parallelized. (#nlmixr2 #rstats)

    blog.nlmixr2.org/blog/2024-03-

    #nlmixr2 #rstats
  26. Matthew L Fidler @[email protected] ·

    We have a new nlmixr2 blog entry courtesy of Hitesh Mistry and Nicola Melillo (@NicolaMelillo) detailing how to upscale nlmixr2 using AWS. This is helpful for long running SAEM models. In the future it may be even more interesting with other methods parallelized. (#nlmixr2 #rstats)

    blog.nlmixr2.org/blog/2024-03-

    #nlmixr2 #rstats
  27. Matthew L Fidler @[email protected] ·

    We have a new nlmixr2 blog entry courtesy of Hitesh Mistry and Nicola Melillo (@NicolaMelillo) detailing how to upscale nlmixr2 using AWS. This is helpful for long running SAEM models. In the future it may be even more interesting with other methods parallelized. (#nlmixr2 #rstats)

    blog.nlmixr2.org/blog/2024-03-

    #rstats #nlmixr2
  28. Matthew L Fidler @[email protected] ·

    We have a new nlmixr2 blog entry courtesy of Hitesh Mistry and Nicola Melillo (@NicolaMelillo) detailing how to upscale nlmixr2 using AWS. This is helpful for long running SAEM models. In the future it may be even more interesting with other methods parallelized. (#nlmixr2 #rstats)

    blog.nlmixr2.org/blog/2024-03-

    #nlmixr2 #rstats
  29. Matthew L Fidler @mattfidler ·

    A new version of was released on CRAN today. I will talk about a few features in the future:

    - More flexible mu referencing

    - User defined functions can now be used with nlmixr2 and rxode2

    - Event handling changes

    - Many new estimation methods for population only fitting
    I am very grateful for both the nlmixr2 team and the nlmixr2 users who have helped me get to this point in nlmixr2's development.

    See the blog for more details about the release.

    blog.nlmixr2.org/blog/2024-01-

    #nlmixr2
  30. Matthew L Fidler @[email protected] ·

    A new version of #nlmixr2 was released on CRAN today. I will talk about a few features in the future:

    - More flexible mu referencing

    - User defined functions can now be used with nlmixr2 and rxode2

    - Event handling changes

    - Many new estimation methods for population only fitting
    I am very grateful for both the nlmixr2 team and the nlmixr2 users who have helped me get to this point in nlmixr2's development.

    See the blog for more details about the release.

    blog.nlmixr2.org/blog/2024-01-

    #nlmixr2
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