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  1. 📢📢📢
    and community!

    We are thrilled to announce the "Tools and Methods for Next Generation Electrophysiology" event, happening in Edinburgh from May 27-31.

    Registration link:
    forms.gle/6dEdeR7sD7u6u8rU8

    More info on the event webpage:
    spikeinterface.github.io/spike

  2. 📢📢📢📢📢
    SpikeInterface v0.99.0 has been released on !

    pypi.org/project/spikeinterfac

    Just run this to upgrade your installation:

    >>> pip install --upgrade spikeinterface

    Check out the release notes here:
    spikeinterface.readthedocs.io/

  3. SpikeInterface v0.97.0 has been released on : pypi.org/project/spikeinterfac

    Just run:
    >>> pip install --upgrade spikeinterface

    The new release includes several new features and updates to the package! A detailed list of changes can be found here:
    spikeinterface.readthedocs.io/

    Happy to everyone!!!

  4. Happy new year from the SpikeInterface team! 🥳
    2023 will be full of updates and new exciting features!

    If you'd like to support us and broaden the SI community, please add a ⭐️ to our GitHub page 🙏:
    github.com/SpikeInterface/spik

  5. SpikeInterface is an framework in to analyze extracellular electrophysiology data and perform .

    We believe that spike sorting development should be a collaborative and community effort and we encourage contributors!

    You can read more in the docs:
    spikeinterface.readthedocs.io/

    Follow a tutorial:
    github.com/SpikeInterface/spik

    Check out the source code:
    github.com/SpikeInterface/spik

    Happy to all!

  6. #NeuroMastodon #ephys #spikesorting

    📢📢📢📢📢
    SpikeInterface v0.99.0 has been released on #PyPi!

    pypi.org/project/spikeinterfac

    Just run this to upgrade your installation:

    >>> pip install --upgrade spikeinterface

    Check out the release notes here:
    spikeinterface.readthedocs.io/

  7. #NeuroMastodon #ephys #spikesorting

    📢📢📢📢📢
    SpikeInterface v0.99.0 has been released on #PyPi!

    pypi.org/project/spikeinterfac

    Just run this to upgrade your installation:

    >>> pip install --upgrade spikeinterface

    Check out the release notes here:
    spikeinterface.readthedocs.io/

  8. #NeuroMastodon #ephys #spikesorting

    📢📢📢📢📢
    SpikeInterface v0.99.0 has been released on #PyPi!

    pypi.org/project/spikeinterfac

    Just run this to upgrade your installation:

    >>> pip install --upgrade spikeinterface

    Check out the release notes here:
    spikeinterface.readthedocs.io/

  9. #NeuroMastodon #ephys #spikesorting

    SpikeInterface v0.97.0 has been released on #PyPi: pypi.org/project/spikeinterfac

    Just run:
    >>> pip install --upgrade spikeinterface

    The new release includes several new features and updates to the package! A detailed list of changes can be found here:
    spikeinterface.readthedocs.io/

    Happy #spikesorting to everyone!!!

  10. #NeuroMastodon #ephys #spikesorting

    SpikeInterface v0.97.0 has been released on #PyPi: pypi.org/project/spikeinterfac

    Just run:
    >>> pip install --upgrade spikeinterface

    The new release includes several new features and updates to the package! A detailed list of changes can be found here:
    spikeinterface.readthedocs.io/

    Happy #spikesorting to everyone!!!

  11. #NeuroMastodon #ephys #spikesorting

    SpikeInterface v0.97.0 has been released on #PyPi: pypi.org/project/spikeinterfac

    Just run:
    >>> pip install --upgrade spikeinterface

    The new release includes several new features and updates to the package! A detailed list of changes can be found here:
    spikeinterface.readthedocs.io/

    Happy #spikesorting to everyone!!!

  12. #NeuroMastodon #ephys #spikesorting

    SpikeInterface v0.97.0 has been released on #PyPi: pypi.org/project/spikeinterfac

    Just run:
    >>> pip install --upgrade spikeinterface

    The new release includes several new features and updates to the package! A detailed list of changes can be found here:
    spikeinterface.readthedocs.io/

    Happy #spikesorting to everyone!!!

  13. Are you interested in the spiking activity of your neuronal cultures, #brain slices, #organoids, etc.?

    Check out our latest publication in STAR Protocols:
    “Protocol for the enhanced analysis of electrophysiological data from high-density multi-electrode arrays with nicespike and spikeNburst”
    doi.org/10.1016/j.xpro.2025.10

    It provides user-friendly graphical and #Python programming interfaces to spike sorting via template matching thanks to #Kilosort and #spikeinterface (@spikeinterface), and subsequent analysis of #spiking and #bursting activity, networks, and synchrony.

    #neuroscience #brainscience #electrophysiology #brainOrganoids

  14. Spent a month in procrastination to avoid debugging a horribly patched #spikesorting pipeline in MATLAB. Then came to discover @spikeinterface and now I just want to spend my day plotting filtered traces and quality metrics, everything is just so smooth 😍​
    People in #open neuroscience software are pulling out truly amazing things!

  15. #SpikeSorting question:
    Say I would like to use #Klustakwick (3) - I have the .exe of it - with #SpikeInterface , to pre-sort my spikes. But it is not implemented in the available “sorters”.
    “Klusta” is, which seems somewhat similar (made by the same people?) but also quite different. I really like Klustakwick and would just like to try that.
    Any ideas?
    Where is the best place to ask questions about SpikeInterface? I feel like opening an Issue on the GitHub is a bit overkill… 🙏​

  16. Hi, is anyone using #Mountainsort with #Neuralynx data? Are you using #SpikeInterface to convert the input data? Would you share your code? 😃​🙏​
    #SpikeSorting

  17. @chrisXrodgers
    Very good question!
    I have most recently used MountainSort + Phy (via SpikeInterface) and I quite like Phy (for manual refinement of clusters) but not so much Mountainsort - it seemed very conservative. I’ll go back to it soon and tweak the settings a bit. If you want to try it out we have some shared code with the Genzel lab here: github.com/elduvelle/Spikeinte

    But I was also going to try out Kilosort. Do you really not like it?
    Before that KlustaKwik + Tint has been the gold standard for me :) … but maybe it’s time to move on!
    #SpikeSorting #Tetrodes #Electrophysiology

  18. What is #neuronalSpiking? Neurons in the brain use electrical signals to communicate with each other and with the body. Each time a neuron is electrically active and this activity exceeds some threshold we can detect this activity as a spike.

    Here, we used high-dimensional multielectrode arrays (HD-MEA) with thousands of electrodes, able to measure extracellular electrical potentials of single neurons. The recorded data consisted of raw voltage traces sampled at low frequency of 20 kHz for each of thr 4,096 recording channels. We implemented the reading of these data in #spikeinterface and could reuse the spikeinterface methods to run the spike detection and sorting with #Kilosort.

    #SpikeSorting is important because, firstly, neuronal units may span over multiple electrodes, and secondly, an electrode may measure activity from multiple nearby neuronal units. To study biological questions it was essential to measure the spiking activity of real neuronal units instead of electrodes.

  19. What is #neuronalSpiking? Neurons in the brain use electrical signals to communicate with each other and with the body. Each time a neuron is electrically active and this activity exceeds some threshold we can detect this activity as a spike.

    Here, we used high-dimensional multielectrode arrays (HD-MEA) with thousands of electrodes, able to measure extracellular electrical potentials of single neurons. The recorded data consisted of raw voltage traces sampled at low frequency of 20 kHz for each of thr 4,096 recording channels. We implemented the reading of these data in #spikeinterface and could reuse the spikeinterface methods to run the spike detection and sorting with #Kilosort.

    #SpikeSorting is important because, firstly, neuronal units may span over multiple electrodes, and secondly, an electrode may measure activity from multiple nearby neuronal units. To study biological questions it was essential to measure the spiking activity of real neuronal units instead of electrodes.

  20. What is #neuronalSpiking? Neurons in the brain use electrical signals to communicate with each other and with the body. Each time a neuron is electrically active and this activity exceeds some threshold we can detect this activity as a spike.

    Here, we used high-dimensional multielectrode arrays (HD-MEA) with thousands of electrodes, able to measure extracellular electrical potentials of single neurons. The recorded data consisted of raw voltage traces sampled at low frequency of 20 kHz for each of thr 4,096 recording channels. We implemented the reading of these data in #spikeinterface and could reuse the spikeinterface methods to run the spike detection and sorting with #Kilosort.

    #SpikeSorting is important because, firstly, neuronal units may span over multiple electrodes, and secondly, an electrode may measure activity from multiple nearby neuronal units. To study biological questions it was essential to measure the spiking activity of real neuronal units instead of electrodes.

  21. Are you interested in the spiking activity of your neuronal cultures, #brain slices, #organoids, etc.?

    Check out our latest publication in STAR Protocols:
    “Protocol for the enhanced analysis of electrophysiological data from high-density multi-electrode arrays with nicespike and spikeNburst”
    doi.org/10.1016/j.xpro.2025.10

    It provides user-friendly graphical and #Python programming interfaces to spike sorting via template matching thanks to #Kilosort and #spikeinterface (@spikeinterface), and subsequent analysis of #spiking and #bursting activity, networks, and synchrony.

    #neuroscience #brainscience #electrophysiology #brainOrganoids

  22. Are you interested in the spiking activity of your neuronal cultures, #brain slices, #organoids, etc.?

    Check out our latest publication in STAR Protocols:
    “Protocol for the enhanced analysis of electrophysiological data from high-density multi-electrode arrays with nicespike and spikeNburst”
    doi.org/10.1016/j.xpro.2025.10

    It provides user-friendly graphical and #Python programming interfaces to spike sorting via template matching thanks to #Kilosort and #spikeinterface (@spikeinterface), and subsequent analysis of #spiking and #bursting activity, networks, and synchrony.

    #neuroscience #brainscience #electrophysiology #brainOrganoids

  23. Are you interested in the spiking activity of your neuronal cultures, #brain slices, #organoids, etc.?

    Check out our latest publication in STAR Protocols:
    “Protocol for the enhanced analysis of electrophysiological data from high-density multi-electrode arrays with nicespike and spikeNburst”
    doi.org/10.1016/j.xpro.2025.10

    It provides user-friendly graphical and #Python programming interfaces to spike sorting via template matching thanks to #Kilosort and #spikeinterface (@spikeinterface), and subsequent analysis of #spiking and #bursting activity, networks, and synchrony.

    #neuroscience #brainscience #electrophysiology #brainOrganoids

  24. Are you interested in the spiking activity of your neuronal cultures, #brain slices, #organoids, etc.?

    Check out our latest publication in STAR Protocols:
    “Protocol for the enhanced analysis of electrophysiological data from high-density multi-electrode arrays with nicespike and spikeNburst”
    doi.org/10.1016/j.xpro.2025.10

    It provides user-friendly graphical and #Python programming interfaces to spike sorting via template matching thanks to #Kilosort and #spikeinterface (@spikeinterface), and subsequent analysis of #spiking and #bursting activity, networks, and synchrony.

    #neuroscience #brainscience #electrophysiology #brainOrganoids